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Extracorporeal renal replacement therapy and blood purification in critical care

Authors

  • Larry D. Cowgill DVM, PhD, DACVIM,

    Corresponding author
    • Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA
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  • Julien Guillaumin Doct. Vet., DACVECC

    1. Emergency and Critical Care Service, Veterinary Medical Center, The Ohio State University, Columbus, OH
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  • The authors declare no conflict of interest.

Address correspondence and reprint requests to

Dr. Larry D. Cowgill, Department of Medicine and Epidemology, 2108 Tupper Hall, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.

Email: ldcowgill@ucdavis.edu

Abstract

Objective

To review indications methods of renal replacement therapies (RRT) and practical considerations for the creation of a RRT program.

Data Sources

Current human and veterinary literature review with a focus on advanced renal physiology and clinical experience in RRT and acute/chronic kidney diseases.

Data Synthesis

Renal replacement therapies encompass intermittent hemodialysis, continuous renal replacement therapy as well as some “hybrid” techniques. Each method of RRT has practical and theoretical advantages but currently there is no evidence that one technique is superior to the other.

Conclusions

RRT is a valuable therapeutic tool for treatment of acute kidney injury and chronic kidney disease. The implementation of an RRT program needs to take into consideration multiple parameters beyond the choice of an RRT platform.

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