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Clinical experience with a lipid-free, ready-made parenteral nutrition solution in dogs: 70 cases (2006–2012)


  • Dr. Gajanayake's current address: Willows Referral Service, Highlands Road, Shirley, Solihull, West Midlands B90 4NH, United Kingdom.

  • Dr. Gajanayake's residency program was partly sponsored by Waltham Pet Care.

  • Presented in abstract form at the ACVIM Forum in Anaheim, CA, June 2010.

  • Dr. Chan is the Editor-in-Chief of the Journal but did not participate in the peer-review process other than as an author.

  • The authors declare no other conflict of interest.

Address correspondence and reprint requests to

Mr. Isuru Gajanayake, Willows Referral Service, Highlands Road, Shirley, Solihull, West Midlands B90 4NH, United Kingdom.




To review the clinical use of a lipid-free, ready-made amino acid and glucose parenteral nutrition (PN) solution in dogs.


Retrospective study of dogs from 2006 to 2012 that received this form of PN.


University veterinary teaching hospital.


Seventy dogs presented to the hospital for treatment of various diseases in which PN was used as part of patient management. Dogs were administered PN at the discretion of the primary clinician.


A lipid-free, ready-made solution containing amino acid (59 g/L) and dextrose (100 g/L) was administered intravenously as a constant rate infusion to provide nutritional support.

Measurements and Main Results

PN was provided for a median of 2.2 days (range 0.5–9.5 days) in the 70 dogs, totaling 168 days of PN. The PN provided a median of 5.5 g/100 kcal of protein (range 1–9.5 g/100 kcal) and a median of 2.2 mg/kg of bodyweight per minute (range 0.8–5.2 mg/kg/min) of glucose, which reflected a median of 57% of the resting energy requirement (range 9–100%). Metabolic complications developed in 43 of 67 dogs where these data were recorded, but the development of hyperkalemia was the only complication associated with a poor outcome (eg, death or euthanasia). Mechanical complications were seen in 28 dogs, and all but one of these occurred when PN was delivered through peripheral catheters. Septic complications were confirmed in 5 dogs.


This form of PN is suitable for clinical use and can provide both protein and calories to ill dogs. It was, however, associated with a high rate of complications and requires careful patient monitoring.