The authors declare no conflict of interests.
Status epilepticus attributed to inadvertent intrathecal injection of cefazolin during myelography
Article first published online: 4 DEC 2013
© Veterinary Emergency and Critical Care Society 2013
Journal of Veterinary Emergency and Critical Care
Volume 23, Issue 6, pages 631–636, November/December 2013
How to Cite
Griffith, C. A. and Hoffmann, D. E. (2013), Status epilepticus attributed to inadvertent intrathecal injection of cefazolin during myelography. Journal of Veterinary Emergency and Critical Care, 23: 631–636. doi: 10.1111/vec.12117
- Issue published online: 4 DEC 2013
- Article first published online: 4 DEC 2013
- Manuscript Accepted: 1 OCT 2013
- Manuscript Received: 29 FEB 2012
- contrast radiography;
To describe a case of status epilepticus believed to be a consequence of inadvertent intrathecal administration of cefazolin in a dog undergoing a myelogram.
A 4-year-old, 6.5 kg, male neutered Dachshund was referred for evaluation of an acute onset hind limb paraparesis. While performing a lumbar myelogram, cefazolin was inadvertently injected into the ventral subarachnoid space. Subsequent refractory seizure activity was attributed to the epileptogenic effects of intrathecally administered cefazolin. Supportive therapy led to eventual complete recovery.
New or Unique Information Provided
Although epileptogenic effects of intrathecally administered cefazolin are well documented in the human and experimental animal model literature, to the authors’ knowledge this has not been characterized in the veterinary literature. This case highlights the need to be diligent and mindful when one administers medications, and describes the management of a dog adversely affected as a consequence of a medical error.