The authors declare no conflict of interest.
Prognostic value of echocardiographic and Doppler parameters in horses admitted for colic complicated by systemic inflammatory response syndrome
Article first published online: 1 APR 2014
© Veterinary Emergency and Critical Care Society 2014
Journal of Veterinary Emergency and Critical Care
Volume 24, Issue 3, pages 302–310, May/June 2014
How to Cite
Borde, L., Amory, H., Grulke, S., Leroux, A. A., Houben, R. M., Detilleux, J. and Sandersen, C. C. (2014), Prognostic value of echocardiographic and Doppler parameters in horses admitted for colic complicated by systemic inflammatory response syndrome. Journal of Veterinary Emergency and Critical Care, 24: 302–310. doi: 10.1111/vec.12177
Presented in part at the 4th Congress of European College of Equine Internal Medicine, Hannover, Germany.
- Issue published online: 24 JUN 2014
- Article first published online: 1 APR 2014
- Manuscript Accepted: 4 FEB 2014
- Manuscript Received: 31 OCT 2012
- equine intensive care;
To assess the prognostic value of echocardiographic parameters of left ventricular (LV) function in horses with systemic inflammatory response syndrome (SIRS).
Prospective observational study.
Veterinary teaching hospital.
Forty-one horses admitted for colic with clinical evidence of SIRS.
All horses underwent Doppler echocardiographic examination on admission. LV echocardiographic parameters, including pulsed-wave tissue Doppler imaging parameters, were compared between nonsurvivors (n = 29) and horses that survived to discharge (n = 12).
Measurements and Main Results
With comparable heart rate and LV preload estimate, LV stroke volume index, the velocity time integral, deceleration time, ejection time of Doppler aortic flow, and peak early diastolic myocardial velocity were lower in the nonsurviving than in the surviving horses, while pre-ejection period to ejection time ratio (PEP/ET) of Doppler aortic flow and the peak early diastolic filling velocity to peak early diastolic myocardial velocity ratio (E/Em) were higher (P < 0.05). A cut-off value of 0.26 for PEP/ET predicted mortality with 100% sensitivity and 42% specificity (area under the receiver operating characteristic curve: 0.71), whereas a cut-off value of 2.67 for E/Em predicted mortality with 100% sensitivity and 83% specificity (area under the receiver operating characteristic curve: 0.89).
Echocardiography may provide prognostic information in colic horses with clinical evidence of SIRS. Especially, PEP/ET and E/Em could be useful markers of systolic and diastolic dysfunction, respectively, to detect horses with a high risk of death requiring more intensive cardiovascular monitoring as it has been reported in human patients with septic shock.