Unilateral microphthalmia or anophthalmia in eight pythons (Pythonidae)
Article first published online: 7 AUG 2014
© 2014 American College of Veterinary Ophthalmologists
Special Issue: Exotics and Wildlife
Volume 18, Issue Supplement s1, pages 23–29, January 2015
How to Cite
Da Silva, M.-A. O., Bertelsen, M. F., Wang, T., Pedersen, M., Lauridsen, H. and Heegaard, S. (2015), Unilateral microphthalmia or anophthalmia in eight pythons (Pythonidae). Veterinary Ophthalmology, 18: 23–29. doi: 10.1111/vop.12198
- Issue published online: 18 JAN 2015
- Article first published online: 7 AUG 2014
- Ministry of Science, Technology and Innovation. Grant Number: 10-091595
- Alfred Benzon Foundation
To provide morphological descriptions of microphthalmia or anophthalmia in eight pythons using microcomputerized tomography (μCT), magnetic resonance imaging (MRI), and histopathology.
Seven Burmese pythons (Python bivittatus) and one ball python (P. regius) with clinically normal right eyes and an abnormal or missing left eye.
At the time of euthanasia, four of the eight snakes underwent necropsy. Hereafter, the heads of two Burmese pythons and one ball python were examined using μCT, and another Burmese python was subjected to MRI. Following these procedures, the heads of these four pythons along with the heads of an additional three Burmese pythons were prepared for histology.
All eight snakes had left ocular openings seen as dermal invaginations between 0.2 and 2.0 mm in diameter. They also had varying degrees of malformations of the orbital bones and a limited presence of nervous, glandular, and muscle tissue in the posterior orbit. Two individuals had small but identifiable eyes. Furthermore, remnants of the pigmented embryonic framework of the hyaloid vessels were found in the anophthalmic snakes. Necropsies revealed no other macroscopic anomalies.
Eight pythons with unilateral left-sided microphthalmia or anophthalmia had one normal eye and a left orbit with malformed or incompletely developed ocular structures along with remnants of fetal structures. These cases lend further information to a condition that is often seen in snakes, but infrequently described.