The risk of transfusion-transmitted HIV from blood donations of men who have sex with men, 12 months after last sex with a man: 2005–2007 estimates from England and Wales

Authors

  • K. L. Davison,

    Corresponding author
    1. NHSBT/HPA Epidemiology Unit, NHS Blood and Transplant, Colindale, London, UK
    • NHSBT/HPA Epidemiology Unit, Immunisation Hepatitis and Blood Safety Department, Health Protection Services, Health Protection Agency, Colindale, London, UK
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  • S. Conti,

    1. Statistics Unit, Health Protection Agency, Colindale, London, UK
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  • S. R. Brailsford

    1. NHSBT/HPA Epidemiology Unit, Immunisation Hepatitis and Blood Safety Department, Health Protection Services, Health Protection Agency, Colindale, London, UK
    2. NHSBT/HPA Epidemiology Unit, NHS Blood and Transplant, Colindale, London, UK
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Correspondence: K. L. Davison. Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency, 61 Colindale Avenue. London NW9 5EQ, UK.

E-mail: katy.davison@hpa.org.uk

Abstract

The risk of transfusion-transmitted HIV infection under (i) permanent exclusion and (ii) 12-month deferral of MSM in England and Wales during 2005–2007 was estimated. Assuming equal compliance with both scenarios, estimated risk under a 12-month deferral (0.228/million donations [range 0·168–0·306/million donations]) was only marginally greater (0·5%) than that under lifetime exclusion (0·227/million donations [range 0·157–0.318/million donations]), with one extra-HIV infectious donation every 455 years. Poorer compliance of MSM with a 12-month deferral would be expected to increase the estimated risk, whereas improved compliance could decrease risk by up to 29·1%.

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