This work was performed at the College of Veterinary Medicine, The Ohio State University, Columbus, OH.
EVALUATION OF TRADITIONAL AND NOVEL RADIOGRAPHIC VERTEBRAL RATIOS IN GREAT DANES WITH VERSUS WITHOUT CERVICAL SPONDYLOMYELOPATHY
Article first published online: 3 APR 2014
© 2014 American College of Veterinary Radiology
Veterinary Radiology & Ultrasound
Volume 55, Issue 5, pages 488–495, September/October 2014
How to Cite
Martin-Vaquero, P. and da Costa, R. C. (2014), EVALUATION OF TRADITIONAL AND NOVEL RADIOGRAPHIC VERTEBRAL RATIOS IN GREAT DANES WITH VERSUS WITHOUT CERVICAL SPONDYLOMYELOPATHY. Veterinary Radiology & Ultrasound, 55: 488–495. doi: 10.1111/vru.12159
Funding sources: This work was supported by the Great Dane Club of America, an Intramural Canine grant from The Ohio State University, College of Veterinary Medicine, and the Award Number Grant UL1TR001070 for The Ohio State University Center for Clinical and Translational Science (CCTS) from the National Center for Advancing Translational Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Advancing Translational Sciences or the National Institutes of Health.
- Issue published online: 12 SEP 2014
- Article first published online: 3 APR 2014
- Manuscript Accepted: 7 JAN 2014
- Manuscript Received: 16 NOV 2013
- Great Dane Club of America
- The Ohio State University, College of Veterinary Medicine. Grant Number: UL1TR001070
- cervical spine;
- wobbler syndrome
Great Danes are predisposed to osseous-associated cervical spondylomyelopathy (Wobbler syndrome). The first aim of this prospective study was to compare values measured using previously published intravertebral and intervertebral ratio methods and a novel ventrodorsal ratio method in radiographs of clinically normal and affected Great Danes. The second aim was to determine whether these ratios could be used as predictors of sites of spinal cord compression based on magnetic resonance imaging (MRI). Thirty dogs (15 normal, 15 affected) were prospectively enrolled. Lateral and ventrodorsal radiographs were obtained and six measurements were recorded from C3-T1. For each vertebral location, intravertebral ratios and intervertebral ratios were calculated from lateral views, and the ratio of the distance between the articular process joints vs. vertebral body width (novel ventrodorsal ratio) was calculated from ventrodorsal views. Values for these three ratios were compared, by vertebral location and dog group. Intravertebral and intervertebral ratios did not differ between dog groups. The ventrodorsal ratio was significantly smaller in affected Great Danes at C5–6 (P = 0.005) and C6–7 (P < 0.001). The ventrodorsal ratio was significantly associated with MRI presence of spinal cord compression. For each 0.1 unit increase in this ratio value, there was a 65% decrease in the odds of spinal cord compression being present at that site, independent of vertebral location (P = 0.002). Findings from this study supported use of the novel ventrodorsal ratio as an initial radiographic screening method for Great Danes with suspected cervical spondylomyelopathy.