Get access

EVALUATION OF TRADITIONAL AND NOVEL RADIOGRAPHIC VERTEBRAL RATIOS IN GREAT DANES WITH VERSUS WITHOUT CERVICAL SPONDYLOMYELOPATHY

Authors

  • Paula Martin-Vaquero,

    Corresponding author
    1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH
    • Address correspondence and reprint requests to Paula Martin-Vaquero, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43210; E-mail: paulagu83@gmail.com

    Search for more papers by this author
  • Ronaldo C. da Costa

    1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH
    Search for more papers by this author

  • This work was performed at the College of Veterinary Medicine, The Ohio State University, Columbus, OH.

  • Funding sources: This work was supported by the Great Dane Club of America, an Intramural Canine grant from The Ohio State University, College of Veterinary Medicine, and the Award Number Grant UL1TR001070 for The Ohio State University Center for Clinical and Translational Science (CCTS) from the National Center for Advancing Translational Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Advancing Translational Sciences or the National Institutes of Health.

Abstract

Great Danes are predisposed to osseous-associated cervical spondylomyelopathy (Wobbler syndrome). The first aim of this prospective study was to compare values measured using previously published intravertebral and intervertebral ratio methods and a novel ventrodorsal ratio method in radiographs of clinically normal and affected Great Danes. The second aim was to determine whether these ratios could be used as predictors of sites of spinal cord compression based on magnetic resonance imaging (MRI). Thirty dogs (15 normal, 15 affected) were prospectively enrolled. Lateral and ventrodorsal radiographs were obtained and six measurements were recorded from C3-T1. For each vertebral location, intravertebral ratios and intervertebral ratios were calculated from lateral views, and the ratio of the distance between the articular process joints vs. vertebral body width (novel ventrodorsal ratio) was calculated from ventrodorsal views. Values for these three ratios were compared, by vertebral location and dog group. Intravertebral and intervertebral ratios did not differ between dog groups. The ventrodorsal ratio was significantly smaller in affected Great Danes at C5–6 (P = 0.005) and C6–7 (P < 0.001). The ventrodorsal ratio was significantly associated with MRI presence of spinal cord compression. For each 0.1 unit increase in this ratio value, there was a 65% decrease in the odds of spinal cord compression being present at that site, independent of vertebral location (P = 0.002). Findings from this study supported use of the novel ventrodorsal ratio as an initial radiographic screening method for Great Danes with suspected cervical spondylomyelopathy.

Ancillary