Both authors contributed equally to this work.
Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation
Article first published online: 5 FEB 2013
© 2013 John Wiley & Sons A/S
Volume 20, Issue 1, pages 27–35, January/February 2013
How to Cite
Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation. Xenotransplantation 2013; 20: 27–35. © 2013 John Wiley & Sons A/S., , , , , , , , , , , , , .
- Issue published online: 5 FEB 2013
- Article first published online: 5 FEB 2013
- Manuscript Accepted: 20 DEC 2012
- Manuscript Received: 1 OCT 2012
|xen12019-sup-0001-FigS1.docx||Word document||171K||Figure S1. Schema describing the process used to create double knockout cells and fetuses.|
|xen12019-sup-0002-FigS2.jpg||image/jpg||677K||Figure S2. Analyses of CMAH Gene Disruptions.|
|xen12019-sup-0003-FigS3.jpg||image/jpg||443K||Figure S3. Wild type and double-KO liver derived porcine cells stained with (a) anti-Neu5Gc antibody (cyan), appropriate isotype control antibody and (b) IB4 lectin (red).|
|xen12019-sup-0004-FigS4.jpg||image/jpg||468K||Figure S4. Individual curves for antibody mediated complement dependent cytotoxicity of 10 healthy human serum samples against GGTA1-KO (red) and double-KO (blue) PBMCs.|
|xen12019-sup-0005-FigS5.jpg||image/jpg||646K||Figure S5. Antibody binding and antibody-mediated complement-dependent cytotoxicity assays.|
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