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References

  • Bachschmid M, Van Der Loo B, Schuler K, Labugger R, Thurau S, Eto M, Kilo J, Holz R, Luscher TF & Ullrich V (2004). Oxidative stress-associated vascular aging is independent of the protein kinase C/NAD(P)H oxidase pathway. Arch Gerontol Geriatr 38, 181190.
  • Beckman KB & Ames BN (1998). Mitochondrial aging: open questions. Ann N Y Acad Sci 854, 118127.
  • Butler R, Morris AD, Belch JJ, Hill A & Struthers AD (2000). Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension 35, 746751.
  • Cardillo C, Kilcoyne CM, Cannon RO 3rd, Quyyumi AA & Panza JA (1997). Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients. Hypertension 30, 5763.
  • Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J & Deanfield JE (1994). Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol 24, 471476.
  • Colombo PC, Ashton AW, Celaj S, Talreja A, Banchs JE, Dubois NB, Marinaccio M, Malla S, Lachmann J, Ware JA & Le Jemtel TH (2002). Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium. J Appl Physiol 92, 13311338.
  • Colombo PC, Banchs JE, Celaj S, Talreja A, Lachmann J, Malla S, DuBois NB, Ashton AW, Latif F, Jorde UP, Ware JA & LeJemtel TH (2005). Endothelial cell activation in patients with decompensated heart failure. Circulation 111, 5862.
  • Cosentino F, Patton S, D'Uscio LV, Werner ER, Werner-Felmayer G, Moreau P, Malinski T & Luscher TF (1998). Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats. J Clin Invest 101, 15301537.
  • Cote CG, Yu FS, Zulueta JJ, Vosatka RJ & Hassoun PM (1996). Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide. Am J Physiol 271, L869L874.
  • Csiszar A, Ungvari Z, Edwards JG, Kaminski P, Wolin MS, Koller A & Kaley G (2002). Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res 90, 11591166.
  • Day RO, Miners J, Birkett DJ, Graham GG & Whitehead A (1988). Relationship between plasma oxipurinol concentrations and xanthine oxidase activity in volunteers dosed with allopurinol. Br J Clin Pharmacol 26, 429434.
  • DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H & Seals DR (2000). Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 102, 13511357.
  • Dinenno FA, Dietz NM & Joyner MJ (2002). Aging and forearm postjunctional alpha-adrenergic vasoconstriction in healthy men. Circulation 106, 13491354.
  • Dinenno FA, Tanaka H, Monahan KD, Clevenger CM, Eskurza I, DeSouza CA & Seals DR (2001). Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men. J Physiol 534, 287295.
  • Dupont GP, Huecksteadt TP, Marshall BC, Ryan US, Michael JR & Hoidal JR (1992). Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells. J Clin Invest 89, 197202.
  • Eskurza I, Monahan KD, Robinson JA & Seals DR (2004). Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol 556, 315324.
  • Eskurza I, Myerburgh LA, Kahn ZD & Seals DR (2005). Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol 568, 10571065.
  • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (2001). Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adults Treatment Panel III). JAMA 285, 24862497.
  • Farquharson CA, Butler R, Hill A, Belch JJ & Struthers AD (2002). Allopurinol improves endothelial dysfunction in chronic heart failure. Circulation 106, 221226.
  • Feng L, Stern DM & Pile-Spellman J (1999). Human endothelium: endovascular biopsy and molecular analysis. Radiology 212, 655664.
  • Godber BL, Doel JJ, Durgan J, Eisenthal R & Harrison R (2000). A new route to peroxynitrite: a role for xanthine oxidoreductase. FEBS Lett 475, 9396.
  • Guthikonda S, Sinkey C, Barenz T & Haynes WG (2003). Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers. Circulation 107, 416421.
  • Guthikonda S, Woods K, Sinkey CA & Haynes WG (2004). Role of xanthine oxidase in conduit artery endothelial dysfunction in cigarette smokers. Am J Cardiol 93, 664668.
  • Hamilton CA, Brosnan MJ, McIntyre M, Graham D & Dominiczak AF (2001). Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 37, 529534.
  • Hassoun PM, Yu FS, Zulueta JJ, White AC & Lanzillo JJ (1995). Effect of nitric oxide and cell redox status on the regulation of endothelial cell xanthine dehydrogenase. Am J Physiol 268, L809L817.
  • Houston M, Estevez A, Chumley P, Aslan M, Marklund S, Parks DA & Freeman BA (1999). Binding of xanthine oxidase to vascular endothelium. Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling. J Biol Chem 274, 49854994.
  • Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C & Luscher TF (1995). Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 91, 13141319.
  • Krabbe KS, Pedersen M & Bruunsgaard H (2004). Inflammatory mediators in the elderly. Exp Gerontol 39, 687699.
  • Lakatta EG & Levy D (2003). Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a ‘set up’ for vascular disease. Circulation 107, 139146.
  • Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J & Salonen JT (2002). The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288, 27092716.
  • Lind L, Fors N, Hall J, Marttala K & Stenborg A (2005). A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly. The prospective investigation of the vasculature in uppsala seniors (PIVUS) study. Arterioscler Thromb Vasc Biol 25, 23682375.
  • Milstien S & Katusic Z (1999). Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263, 681684.
  • Mitchell GF, Parise H, Vita JA, Larson MG, Warner E, Keaney JF Jr, Keyes MJ, Levy D, Vasan RS & Benjamin EJ (2004). Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension 44, 134139.
  • Moreau KL, Donato AJ, Seals DR, Dinenno FA, Blackett SD, Hoetzer GL, Desouza CA & Tanaka H (2002). Arterial intima-media thickness: site-specific associations with HRT and habitual exercise. Am J Physiol Heart Circ Physiol 283, H1409H1417.
  • Mullen MJ, Kharbanda RK, Cross J, Donald AE, Taylor M, Vallance P, Deanfield JE & MacAllister RJ (2001). Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res 88, 145151.
  • Pyke KE & Tschakovsky ME (2005). The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol 568, 357369.
  • Rajagopalan S, Brook R, Mehta RH, Supiano M & Pitt B (2002). Effect of losartan in aging-related endothelial impairment. Am J Cardiol 89, 562566.
  • Sakuma S, Fujimoto Y, Sakamoto Y, Uchiyama T, Yoshioka K, Nishida H & Fujita T (1997). Peroxynitrite induces the conversion of xanthine dehydrogenase to oxidase in rabbit liver. Biochem Biophys Res Commun 230, 476479.
  • Singh N, Prasad S, Singer DR & MacAllister RJ (2002). Ageing is associated with impairment of nitric oxide and prostanoid dilator pathways in the human forearm. Clin Sci (Lond) 102, 595600.
  • Spiekermann S, Landmesser U, Dikalov S, Bredt M, Gamez G, Tatge H, Reepschlager N, Hornig B, Drexler H & Harrison DG (2003). Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 107, 13831389.
  • Taddei S, Virdis A, Ghiadoni L, Salvetti G, Bernini G, Magagna A & Salvetti A (2001). Age-related reduction of NO availability and oxidative stress in humans. Hypertension 38, 274279.
  • Ungvari Z, Csiszar A & Kaley G (2004). Vascular inflammation in aging. Herz 29, 733740.
  • Van Der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V & Luscher TF (2000). Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med 192, 17311744.
  • Van Pelt RE, Davy KP, Stevenson ET, Wilson TM, Jones PP, Desouza CA & Seals DR (1998). Smaller differences in total and regional adiposity with age in women who regularly perform endurance exercise. Am J Physiol 275, E626E634.
  • Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N & Masters BS, Karoui H, Tordo P & Pritchard KA Jr (1998). Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci U S A 95, 92209225.