This report was presented at a symposium on Organization and function of neuronal circuits in movement control, which took place Trolleholm Castle (Lund), Sweden on 27–28 May, 2011.
Information to cerebellum on spinal motor networks mediated by the dorsal spinocerebellar tract
Article first published online: 17 MAY 2013
© 2013 The Authors. The Journal of Physiology © 2013 The Physiological Society
The Journal of Physiology
Volume 591, Issue 22, pages 5433–5443, November 2013
How to Cite
Stecina, K., Fedirchuk, B. and Hultborn, H. (2013), Information to cerebellum on spinal motor networks mediated by the dorsal spinocerebellar tract. The Journal of Physiology, 591: 5433–5443. doi: 10.1113/jphysiol.2012.249110
- Issue published online: 14 NOV 2013
- Article first published online: 17 MAY 2013
- Accepted manuscript online: 17 APR 2013 12:18PM EST
- (Received 27 November 2012; accepted after revision 9 April 2013; first published online 22 April 2013)
Abstract The main objective of this review is to re-examine the type of information transmitted by the dorsal and ventral spinocerebellar tracts (DSCT and VSCT respectively) during rhythmic motor actions such as locomotion. Based on experiments in the 1960s and 1970s, the DSCT was viewed as a relay of peripheral sensory input to the cerebellum in general, and during rhythmic movements such as locomotion and scratch. In contrast, the VSCT was seen as conveying a copy of the output of spinal neuronal circuitry, including those circuits generating rhythmic motor activity (the spinal central pattern generator, CPG). Emerging anatomical and electrophysiological information on the putative subpopulations of DSCT and VSCT neurons suggest differentiated functions for some of the subpopulations. Multiple lines of evidence support the notion that sensory input is not the only source driving DSCT neurons and, overall, there is a greater similarity between DSCT and VSCT activity than previously acknowledged. Indeed the majority of DSCT cells can be driven by spinal CPGs for locomotion and scratch without phasic sensory input. It thus seems natural to propose the possibility that CPG input to some of these neurons may contribute to distinguishing sensory inputs that are a consequence of the active locomotion from those resulting from perturbations in the external world.