We have investigated the influence of the linear accelerator (LINAC) monitor chamber calibration on the dosimetry of Siemens Virtual Wedge™ (VW.) The doses delivered in the three phases of wedge delivery (initial gap, sweep portion, and open field) utilize the ionization current generated in two dose monitoring ion chambers (MONITOR 1 and MONITOR 2) in the LINAC to control the wedge delivery. We intentionally offset the calibration of each of these chambers by and observed up to a 13% change in the dose along the wedge profile for a beam at a field size of . If the calibration of one of the two dose monitoring chambers changed independently then the relative dose at points along the wedge profile were affected. Furthermore, the percentage change in dose varied across the wedge profile thereby affecting the wedge angle as well as the central axis wedge factor. We also present equations for calculating the change in dose at a position along the wedge profile as a function of monitor chamber calibration. A comparison with measurement showed that our theoretical predictions were accurate to within . The equations have proven useful tools in evaluating periodic drifts in VW dosimetry.