Comparison of radiograph-based texture analysis and bone mineral density with three-dimensional microarchitecture of trabecular bone
Hip fracture is a serious health problem and textural methods are being developed to assess bone quality. The authors aimed to perform textural analysis at femur on high-resolution digital radiographs compared to three-dimensional (3D) microarchitecture comparatively to bone mineral density.
In univariate analysis, the correlation coefficients between 2D textural features and 3D morphological parameters reached 0.83 at the FH and 0.79 at the GT. In multivariate canonical correlation analysis, coefficients of the first component reached 0.95 at the FH and 0.88 at the GT.
Digital radiographs, widely available and economically viable, are an alternative method for evaluating bone microarchitectural structure.