SU-E-J-191: Motion Prediction Using Extreme Learning Machine in Image Guided Radiotherapy

Authors

  • Jia J,

    1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031, China
    2. Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province, Hefei 230031, China
    3. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, SuZhou, China
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  • Cao R,

    1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031, China
    2. Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province, Hefei 230031, China
    3. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, SuZhou, China
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  • Pei X,

    1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031, China
    2. Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province, Hefei 230031, China
    3. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, SuZhou, China
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  • Wang H,

    1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031, China
    2. Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province, Hefei 230031, China
    3. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, SuZhou, China
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  • Hu L

    1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031, China
    2. Engineering Technology Research Center of Accurate Radiotherapy of Anhui Province, Hefei 230031, China
    3. Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, SuZhou, China
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Abstract

Purpose:

Real-time motion tracking is a critical issue in image guided radiotherapy due to the time latency caused by image processing and system response. It is of great necessity to fast and accurately predict the future position of the respiratory motion and the tumor location.

Methods:

The prediction of respiratory position was done based on the positioning and tracking module in ARTS-IGRT system which was developed by FDS Team (www.fds.org.cn). An approach involving with the extreme learning machine (ELM) was adopted to predict the future respiratory position as well as the tumor's location by training the past trajectories. For the training process, a feed-forward neural network with one single hidden layer was used for the learning. First, the number of hidden nodes was figured out for the single layered feed forward network (SLFN). Then the input weights and hidden layer biases of the SLFN were randomly assigned to calculate the hidden neuron output matrix. Finally, the predicted movement were obtained by applying the output weights and compared with the actual movement. Breathing movement acquired from the external infrared markers was used to test the prediction accuracy. And the implanted marker movement for the prostate cancer was used to test the implementation of the tumor motion prediction.

Results:

The accuracy of the predicted motion and the actual motion was tested. Five volunteers with different breathing patterns were tested. The average prediction time was 0.281s. And the standard deviation of prediction accuracy was 0.002 for the respiratory motion and 0.001 for the tumor motion.

Conclusion:

The extreme learning machine method can provide an accurate and fast prediction of the respiratory motion and the tumor location and therefore can meet the requirements of real-time tumor-tracking in image guided radiotherapy.

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