SU-E-T-50: A Multi-Institutional Study of Independent Dose Verification Software Program for Lung SBRT

Authors

  • Kawai D,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Takahashi R,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Kamima T,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Baba H,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Yamamoto T,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Kubo Y,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Ishibashi S,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Higuchi Y,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Takahashi H,

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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  • Tachibana H

    1. Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture
    2. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    3. The Cancer Institute Hospital of JFCR, Koutou-ku, Tokyo
    4. The National Cancer Center Hospital East, Kashiwa-city, Chiba prefecture
    5. Otemae Hospital, Chuou-ku, Osaka-city
    6. Otemae Hospital, Chuou-ku, Osaka-city
    7. Sasebo City General Hospital, Sasebo, Nagasaki
    8. Sasebo City General Hospital, Sasebo, Nagasaki
    9. St Lukes International Hospital, Chuou-ku, Tokyo
    10. National Cancer Center Hospital East, Kashiwa, Chiba
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Abstract

Purpose:

The accuracy of dose distribution depends on treatment planning system especially in heterogeneity-region. The tolerance level (TL) of the secondary check using the independent dose verification may be variable in lung SBRT plans. We conducted a multi-institutional study to evaluate the tolerance level of lung SBRT plans shown in the AAPM TG114.

Methods:

Five institutes in Japan participated in this study. All of the institutes used a same independent dose verification software program (Simple MU Analysis: SMU, Triangle Product, Ishikawa, JP), which is Clarkson-based and CT images were used to compute radiological path length. Analytical Anisotropic Algorithm (AAA), Pencil Beam Convolution with modified Batho-method (PBC-B) and Adaptive Convolve (AC) were used for lung SBRT planning. A measurement using an ion-chamber was performed in a heterogeneous phantom to compare doses from the three different algorithms and the SMU to the measured dose. In addition to it, a retrospective analysis using clinical lung SBRT plans (547 beams from 77 patients) was conducted to evaluate the confidence limit (CL, Average±2SD) in dose between the three algorithms and the SMU.

Results:

Compared to the measurement, the AAA showed the larger systematic dose error of 2.9±3.2% than PBC-B and AC. The Clarkson-based SMU showed larger error of 5.8±3.8%. The CLs for clinical plans were 7.7±6.0 % (AAA), 5.3±3.3 % (AC), 5.7±3.4 % (PBC -B), respectively.

Conclusion:

The TLs from the CLs were evaluated. A Clarkson-based system shows a large systematic variation because of inhomogeneous correction. The AAA showed a significant variation. Thus, we must consider the difference of inhomogeneous correction as well as the dependence of dose calculation engine.

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