MO-E-BRD-01: Is Non-Invasive Image-Guided Breast Brachytherapy Good?

Authors


Abstract

Is Non-invasive Image-Guided Breast Brachytherapy Good? – Jess Hiatt, MS

Non-invasive Image-Guided Breast Brachytherapy (NIBB) is an emerging therapy for breast boost treatments as well as Accelerated Partial Breast Irradiation (APBI) using HDR surface breast brachytherapy. NIBB allows for smaller treatment volumes while maintaining optimal target coverage. Considering the real-time image-guidance and immobilization provided by the NIBB modality, minimal margins around the target tissue are necessary.

Accelerated Partial Breast Irradiation in brachytherapy: is shorter better? - Dorin Todor, PhD VCU

A review of balloon and strut devices will be provided together with the origins of APBI: the interstitial multi-catheter implant. A dosimetric and radiobiological perspective will help point out the evolution in breast brachytherapy, both in terms of devices and the protocols/clinical trials under which these devices are used. Improvements in imaging, delivery modalities and convenience are among the factors driving the ultrashort fractionation schedules but our understanding of both local control and toxicities associated with various treatments is lagging. A comparison between various schedules, from a radiobiological perspective, will be given together with a critical analysis of the issues.

  • 1.to review and understand the evolution and development of APBI using brachytherapy methods
  • 2.to understand the basis and limitations of radio-biological ‘equivalence’ between fractionation schedules
  • 3.to review commonly used and proposed fractionation schedules

Intra-operative breast brachytherapy: Is one stop shopping best?- Bruce Libby, PhD. University of Virginia

A review of intraoperative breast brachytherapy will be presented, including the Targit-A and other trials that have used electronic brachytherapy. More modern approaches, in which the lumpectomy procedure is integrated into an APBI workflow, will also be discussed.

Learning Objectives:

  • 1.To review past and current clinical trials for IORT
  • 2.To discuss lumpectomy-scan-plan-treat workflow for IORT

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