Pica With Paradichlorobenzene Mothball Ingestion Associated With Toxic Leukoencephalopathy
Article first published online: 16 FEB 2006
Journal of Neuroimaging
Volume 16, Issue 1, pages 78–81, January 2006
How to Cite
Avila, E., Schraeder, P., Belliappa, A. and Faro, S. (2006), Pica With Paradichlorobenzene Mothball Ingestion Associated With Toxic Leukoencephalopathy. Journal of Neuroimaging, 16: 78–81. doi: 10.1177/1051228405280171
- Issue published online: 16 FEB 2006
- Article first published online: 16 FEB 2006
- Received June 3, 2004, and in revised form January 12, 2005. Accepted for publication June 8, 2005.
- Paradichlorobenzene (PDCB);
- central nervous system (CNS);
- magnetic resonance spectroscopy
This is a case report of central nervous system toxicity associated with paradichlorobenzene (PDCB) ingestion. The patient had ingested mothballs composed of 99.99% PDCB for a period of 7 months. She was admitted for depression and had no neurologic symptoms. Later she developed an acute cerebellar syndrome followed by stupor and coma. An extensive workup was negative except for decreasing levels of PDCB in her serum. Imaging revealed a diffuse leukoencephalopathy. Her clinical picture was attributed to PDCB toxicity.