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The Role of Thymomas in the Development of Myasthenia Gravis


Address for correspondence: Alexander Marx, Institute of Pathology, University of Würzburg, Josef-Schneider-Strasse 2, D-97080 Würzburg, Germany. Voice: +49-931-201-47421; fax: +49-931-201-47505.


Abstract: Thymic pathology occurs in 80–90% of myasthenia gravis patients. Significant associations between different thymic alterations and clinical findings are discussed. To highlight peculiarities in thymoma-associated myasthenia gravis, we briefly review myasthenia gravis associated with thymic lymphofollicular hyperplasia (TFH) and thymic atrophy.