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Liver Transplantation for Treatment of Metastatic Neuroendocrine Tumors

Authors

  • HÅKAN AHLMAN,

    Corresponding author
    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
      Address for correspondence: Dr. Hakan Ahlman, Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden. hakan.ahlman@surgery.gu.se
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  • STYRBJÖRN FRIMAN,

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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  • CHRISTIAN CAHLIN,

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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  • OLA NILSSON,

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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  • SVANTE JANSSON,

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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  • BO WÄNGBERG,

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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  • MICHAEL OLAUSSON

    1. Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden
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Address for correspondence: Dr. Hakan Ahlman, Department of Surgery and Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden. hakan.ahlman@surgery.gu.se

Abstract

Abstract: Liver transplantation can be considered a therapeutic option for patients with neuroendocrine tumors only metastatic to the liver. Important selection criteria are well-differentiated tumors and a low proliferation rate (Ki67 <10%). In this series, orthopic liver transplantation offered good relief of symptoms and long disease-free intervals with initial survival of grafts and patients as in benign disease. The experience with multivisceral transplantation is still limited.

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