The Different Paths to Age One Hundred

Authors

  • THOMAS PERLS

    Corresponding author
    1. Geriatrics Section, New England Centenarian Study, Department of Medicine, Boston University Medical Center, Boston, Massacuhetts 02118, USA
    Search for more papers by this author

Address for correspondence: Thomas Perls, M.D., M.P.H., Geriatrics Section, New England Centenarian Study, Department of Medicine, Boston University Medical Center, Robinson 2400, 88 East Newton Street, Boston, MA 02118. Voice 617-638-6688; fax: 617-638-6671; E-mail: thperls@bu.edu

Abstract

Attaining age 100 is a rare event in industrialized nations, occurring in 1 person per 10,000 in the population. Becoming a centenarian does not appear to be rare because the individual genetic or behavioral factors (such as specific genetic polymorphisms or lack of specific toxic exposures) that enable such longevity are rare, but rather because having the adequate combination of these factors is rare.

Ancillary