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Alexithymia in PTSD
Psychometric and FMRI Studies
Article first published online: 26 JUL 2006
DOI: 10.1196/annals.1364.029
Issue
Annals of the New York Academy of Sciences
Volume 1071, Psychobiology of Posttraumatic Stress Disorder: A Decade of Progress pages 397–400, July 2006
Additional Information
How to Cite
FREWEN, P. A., PAIN, C., DOZOIS, D. J. A. and LANIUS, R. A. (2006), Alexithymia in PTSD. Annals of the New York Academy of Sciences, 1071: 397–400. doi: 10.1196/annals.1364.029
Publication History
- Issue published online: 26 JUL 2006
- Article first published online: 26 JUL 2006
- Abstract
- Article
- References
- Cited By
Keywords:
- alexithymia;
- posttraumatic stress disorder;
- dissociation;
- child abuse;
- child neglect;
- fMRI
Abstract: Two studies examined correlates of alexithymia in posttraumatic stress disorder (PTSD). In study 1 (n= 77 individuals with PTSD and 45 controls) Toronto alexithymia scale (TAS-20) scores were positively correlated with PTSD symptoms, dissociation, and childhood abuse and neglect. In study 2, TAS-20 scores were examined as correlates of functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) response to trauma script imagery. In 16 controls, TAS-20 scores correlated positively with response in medial prefrontal cortex (mPFC), and negatively with response in anterior cingulate cortex (ACC) and thalamus. In 26 individuals with PTSD, TAS-20 scores correlated positively with response in insula, posterior cingulate cortex (PCC), and thalamus, and negatively with response in ACC.