This paper was presented as an oral communication at ICRRD in Logrono.
Rickettsioses in Sub-Saharan Africa
Article first published online: 31 OCT 2006
Annals of the New York Academy of Sciences
How to Cite
PAROLA, P. (2006), Rickettsioses in Sub-Saharan Africa. Annals of the New York Academy of Sciences, 1078: 42–47. doi: 10.1196/annals.1374.005
- Issue published online: 31 OCT 2006
- Article first published online: 31 OCT 2006
- Rickettsia africae;
- Rickettsia conorii;
- Rickettsia aeschlimannii;
- Rickettsia sibirica mongolitimonae;
- Rickettsia prowazekii;
- Rickettsia felis;
- Rickettsia massiliae
Abstract: Although rickettsioses are among the oldest known vector-borne zoonoses, several species or subspecies of rickettsias have been identified in recent years as emerging pathogens throughout the world including in sub-Saharan Africa. To date, six tick-borne spotted fever group pathogenic rickettsias are known to occur in sub-Saharan Africa, including Rickettsia conorii conorii, the agent of Mediterranean spotted fever; R. conorii caspia, the agent of Astrakhan fever; R. africae, the agent of African tick-bite fever; R. aeschlimannii; R. sibirica mongolitimonae; and R. massiliae. On the other hand, fleas have long been known as vectors of the ubiquitous murine typhus, a typhus group rickettsiosis induced by R. typhi. However, a new spotted fever rickettsia, R. felis, has also been found to be associated with fleas, to be a human pathogen, and to be present in sub-Saharan Africa. Finally, R. prowazekii the agent of louse-borne epidemic typhus continues to strikes tens to hundreds of thousands of persons who live in Sub-Saharan with civil war, famine and poor conditions. We present an overview of these rickettsioses occurring in sub-Saharan Africa, focusing on the epidemiological aspects of emerging diseases.