Arousal Regulation, Emotional Flexibility, Medial Amygdala Function, and the Impact of Early Experience
Comments on the Paper of Lewis et al.
Article first published online: 16 FEB 2007
Annals of the New York Academy of Sciences
Volume 1094, Resilience in Children pages 178–192, December 2006
How to Cite
MAYES, L. C. (2006), Arousal Regulation, Emotional Flexibility, Medial Amygdala Function, and the Impact of Early Experience. Annals of the New York Academy of Sciences, 1094: 178–192. doi: 10.1196/annals.1376.018
- Issue published online: 16 FEB 2007
- Article first published online: 16 FEB 2007
- arousal regulation;
- emotional flexibility;
- medial amygdala
Abstract: The balance between optimal levels of emotional arousal and cognitive performance reflects the integration of several dopaminergically and adrenergically regulated neural systems. The amygdalar system is a key region for gating stimulation to cortical regions and the medial amygdala appears to play an especially key role in mediating the fear response. More generally, these arousal regulatory neural systems are key to frustration or stress impact prefrontal cortical function. Further, the threshold for when the level of stress is overwhelming and hence impairs cognitive function reflects minimally genetic and experiential influence. An important interface between Drs. Lewis and Davis's work is how early experience, especially through early parenting, may set the threshold of responsiveness for these arousal regulatory neural systems.