From the Department of Otolaryngology, Washington University School of Medicine, St. Louis, Mo.
Article first published online: 5 JAN 2009
Copyright © 1972 The Triological Society
Volume 82, Issue 5, pages 891–898, May 1972
How to Cite
Swain, R. E. and Stroud, M. H. (1972), Relapsing polychondritis. The Laryngoscope, 82: 891–898. doi: 10.1288/00005537-197205000-00017
Supported by National Institutes of Health Training Grant 5 TO1 NS05190 and National Institutes of Health Research Grant 5 RO1 NS0C563 from NANDS.
- Issue published online: 5 JAN 2009
- Article first published online: 5 JAN 2009
To date only 55 cases of relapsing polychondritis have been reported in the English literature. The present information concerning the history, clinical and laboratory findings, diagnosis, prognosis, and treatment is reviewed. Two unusual cases of this disease which exemplify the extreme variability of the symptomatology among these patients are presented. While asleep one patient developed a classical “saddle nose” deformity which spontaneously improved within three days. The other patient's disease manifested predominately non-cartilaginous symptoms and emphasizes the possibility of an auto-immune or allergic mechanism affecting a molecular target common to both cartilaginous and non-cartilaginous structures.