Presented at the 82nd Annual Meeting of the American Laryngological, Rhinological and Otological Society, Inc., Los Angeles, CA, April 4, 1979.
Article first published online: 5 JAN 2009
Copyright © 1980 The Triological Society
Volume 90, Issue 4, pages 571–575, April 1980
How to Cite
Nichols, R. D., Stine, P. H. and Greenawald, K. J. (1980), Partial laryngectomy after radiation failure. The Laryngoscope, 90: 571–575. doi: 10.1288/00005537-198004000-00002
From Henry Ford Hospital, Detroit, MI.
- Issue published online: 5 JAN 2009
- Article first published online: 5 JAN 2009
Of patients given radiation therapy as primary treatment for limited carcinoma of the larynx, 15-32% will not be cured by this modality. The recurrent tumor and primary site can be encompassed with a partial laryngectomy in a certain number of these individuals. This report reviews the subject of partial laryngectomy after radiation failure and reports experience with 18 patients who had partial laryngectomies to control recurrent or persistent carcinoma after full dose radiation therapy.
Four patients had biopsy cures. Local tumor control was achieved by partial laryngectomy in 10 of 14 patients. Three of 4 partial failures were salvaged with total laryngectomy. Major wound complications were noted in 4 patients. Prolonged healing was observed in most patients. Prognosis is probably as good with partial laryngectomy as with total laryngectomy.