Hashimoto's thyroiditis and carcinoma of the thyroid: Optimal management


  • Anthony P. Sclafani MD,

    Corresponding author
    1. Department of Otolaryngology—Head & Neck Surgery, New York Eye & Ear Infirmary, New York Medical College, New York
    • Department of Otolaryngology—Head and Neck Surgery, New York Eye & Ear Infirmary, 310 East 14 St., New York, NY 10003
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  • Marie Valdes MD,

    1. Department of Surgery, White Plains Hospital, White Plains, NY
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  • Hyun Cho MD

    1. Department of Surgery, Division of Head & Neck Surgery, Beth Israel Medical Center, New York
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  • Presented at the Meeting of the Eastern Section of the American Laryngological, Rhinological and Otological Society, Inc., Boston, January 31, 1992.


Several authors have noted a high incidence of thyroid carcinoma in patients with Hashimoto's thyroiditis (HT), and some have even considered HT a premalignant condition. The authors evaluated all patients with surgically proven HT at Beth Israel Medical Center in New York from 1985 through 1990. Of these 48 patients, 8 (17%) had thyroid carcinoma in addition to HT. No statistically significant difference between patients with and without concurrent carcinoma was noted in the percentage of patients with a dominant mass, irregular thyromegaly, compressive symptoms, suspicious fine needle aspiration biopsies (FNABs), or a cold nodule on thyroid scintigraphy. However, patients with neither a positive FNAB nor a cold nodule were much less likely to have carcinoma than patients with one or both of these tests positive (0% vs. 26%, P±.05). A management scheme for patients with HT is proposed to adequately and efficiently evaluate and treat patients for concurrent thyroid carcinoma.