Contact diode laser microvascular anastomosis appears to be a valuable technique for anastomosing small arteries and veins. Significantly less foreign body reaction and markedly decreased operative time has been shown to be a major advantage of using contact diode laser technology. The authors have found that contact diode laser anastomosis can be performed in vessels as small as 1 mm in size using a 200-μm flat tip synthetic sapphire probe. Light microscopy has shown a significant decrease in foreign body reaction at the level of the anastomosis using laser techniques as compared to standard vessel anastomosis with 10-0 nylon sutures.
The role of fibronectin and changes in collagen associated with laser anastomosis were also explored. Light microscopic electron-microscopic results as well as biotin-avidin immunoperoxidase fibronectin studies will be discussed.