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Keywords:

  • bovine;
  • protoporphyria;
  • genetic;
  • congenital;
  • Limousin

Bovine congenital erythropoietic protoporphyria (BCEPP), a disease caused by a decrease in activity of ferrochelatase enzyme, is most commonly characterised by photosensitisation and seizures. BCEPP is inherited as a simple, autosomal recessive defect, with only homozygote individuals exhibiting clinical signs, and occurs mainly in pure Limousin cattle. There is no specific treatment and the disease can be prevented by avoiding mating of carriers of the defective gene; these can be identified using DNA analysis. This report describes two cases of BCEPP in a pedigree Limousin herd and discusses the investigation of the condition and implications for the herd.