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  • 1
    Melsen F, Mosekilde L 1977 Morphometric and dynamic studies of bone changes in hyperthyroidism. Acta Pathol Microbiol Scand 85A: 141150.
  • 2
    Lewinson D, Harel Z, Shenzer P, Silbermann M, Hochberg Z 1989 Effect of thyroid hormone and growth hormone on recovery from hypothyroidism of epiphyseal growth plate cartilage and its adjacent bone. Endocrinology 124: 937945.
  • 3
    Stevens DA, Hasserjian RP, Robson H, Siebler T, Shalet SM, Williams GR 2000 Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation. J Bone Miner Res 15: 24312442.
  • 4
    Allain TJ, McGregor AM 1993 Thyroid hormones and bone. J Endocrinol 139: 918.
  • 5
    O'Shea PJ, Harvey CB, Suzuki H, Kaneshige M, Kaneshige K, Cheng SY, Williams GR 2003 A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. Mol Endocrinol 17: 14101424.
  • 6
    Harvey CB, O'Shea PJ, Scott AJ, Robson H, Siebler T, Shalet SM, Samarut J, Chassande O, Williams GR 2002 Molecular mechanisms of thyroid hormone effects on bone growth and function. Mol Genet Metab 75: 1730.
  • 7
    Wolf M, Ingbar SH, Moses AC 1989 Thyroid hormone and growth hormone interact to regulate insulin-like growth factor-I messenger ribonucleic acid and circulating levels in the rat. Endocrinology 125: 29052914.
  • 8
    Kindblom JM, Gothe S, Forrest D, Tornell J, Vennstrom B, Ohlsson C 2001 GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1−/−beta−/− mice. J Endocrinol 171: 1522.
  • 9
    Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG 1987 A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature 329: 738741.
  • 10
    Koenig RJ, Brent GA, Warne RL, Larsen PR, Moore DD 1987 Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone. Proc Natl Acad Sci USA 84: 56705674.
  • 11
    Nanto-Salonen K, Muller HL, Hoffman AR, Vu TH, Rosenfeld RG 1993 Mechanisms of thyroid hormone action on the insulin-like growth factor system: All thyroid hormone effects are not growth hormone mediated. Endocrinology 132: 781788.
  • 12
    Ballock RT, Reddi AH 1994 Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium. J Cell Biol 126: 13111318.
  • 13
    Robson H, Siebler T, Stevens DA, Shalet SM, Williams GR 2000 Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. Endocrinology 141: 38873897.
  • 14
    Lazar MA 1993 Thyroid hormone receptors: Multiple forms, multiple possibilities. Endocr Rev 14: 184193.
  • 15
    Freedman LP 1992 Anatomy of the steroid receptor zinc finger region. Endocr Rev 13: 129145.
  • 16
    Chassande O, Fraichard A, Gauthier K, Flamant F, Legrand C, Savatier P, Laudet V, Samarut J 1997 Identification of transcripts initiated from an internal promoter in the c-erbA alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities. Mol Endocrinol 11: 12781290.
  • 17
    Katz D, Lazar MA 1993 Dominant negative activity of an endogenous thyroid hormone receptor variant (alpha 2) is due to competition for binding sites on target genes. J Biol Chem 268: 2090420910.
  • 18
    Williams GR 2000 Cloning and characterization of two novel thyroid hormone receptor beta isoforms. Mol Cell Biol 20: 83298342.
  • 19
    O'Shea PJ, Williams GR 2002 Insight into the physiological actions of thyroid hormone receptors from genetically modified mice. J Endocrinol 175: 553570.
  • 20
    Williams GR, Bland R, Sheppard MC 1994 Characterization of thyroid hormone (T3) receptors in three osteosarcoma cell lines of distinct osteoblast phenotype: Interactions among T3, vitamin D3, and retinoid signaling. Endocrinology 135: 23752385.
  • 21
    Abu EO, Bord S, Horner A, Chatterjee VK, Compston JE 1997 The expression of thyroid hormone receptors in human bone. Bone 21: 137142.
  • 22
    Ballock R, Mita BC, Zhou X, Chen DH, Mink LM 1999 Expression of thyroid hormone receptor isoforms in rat growth plate cartilage in vivo. J Bone Miner Res 14: 15501556.
  • 23
    Forrest D, Erway LC, Ng L, Altschuler R, Curran T 1996 Thyroid hormone receptor beta is essential for development of auditory function. Nat Genet 13: 354357.
  • 24
    Wikstrom L, Johansson C, Salto C, Barlow C, Campos Barros A, Baas F, Forrest D, Thoren P, Vennstrom B 1998 Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1. EMBO J 17: 455461.
  • 25
    Gothe S, Wang Z, Ng L, Kindblom JM, Barros AC, Ohlsson C, Vennstrom B, Forrest D 1999 Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation. Genes Dev 13: 13291341.
  • 26
    Fraichard A, Chassande O, Plateroti M, Roux JP, Trouillas J, Dehay C, Legrand C, Gauthier K, Kedinger M, Malaval L, Rousset B, Samarut J 1997 The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production. EMBO J 16: 44124420.
  • 27
    Gauthier K, Plateroti M, Harvey CB, Williams GR, Weiss RE, Refetoff S, Willott JF, Sundin V, Roux JP, Malaval L, Hara M, Samarut J, Chassande O 2001 Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus. Mol Cell Biol 21: 47484760.
  • 28
    Flamant F, Poguet AL, Plateroti M, Chassande O, Gauthier K, Streichenberger N, Mansouri A, Samarut J 2002 Congenital hypothyroid Pax8(−/−) mutant mice can be rescued by inactivating the TRalpha gene. Mol Endocrinol 16: 2432.
  • 29
    Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS 1998 A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chem Biol 5: 299306.
  • 30
    Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH 2000 The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology 141: 30573064.
  • 31
    Ribeiro MO, Carvalho SD, Schultz JJ, Chiellini G, Scanlan TS, Bianco AC, Brent GA 2001 Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific. J Clin Invest 108: 97105.
  • 32
    Morte B, Manzano J, Scanlan T, Vennstrom B, Bernal J 2002 Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proc Natl Acad Sci USA 99: 39853989.
  • 33
    Manzano J, Morte B, Scanlan TS, Bernal J 2003 Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain. Endocrinology 144: 54805487.
  • 34
    Morte B, Manzano J, Scanlan TS, Vennstrom B, Bernal J 2004 Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms. Endocrinology 145: 13861391.
  • 35
    Furlow JD, Yang HY, Hsu M, Lim W, Ermio DJ, Chiellini G, Scanlan TS 2004 Induction of larval tissue resorption in Xenopus laevis tadpoles by the thyroid hormone receptor agonist GC-1. J Biol Chem 279: 2655526562.
  • 36
    Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH 2003 Spared bone mass in rats treated with thyroid hormone receptor TRbeta-selective compound GC-1. Am J Physiol Endocrinol Metab 285: E1135E1141.
  • 37
    Bianco AC, Silva JE 1987 Nuclear 3,5,3′-triiodothyronine (T3) in brown adipose tissue: Receptor occupancy and sources of T3 as determined by in vivo techniques. Endocrinology 120: 5562.
  • 38
    Fox KM, Kimura S, Plato CC, Kitagawa T 1995 Bilateral asymmetry in bone weight at various skeletal sites of the rat. Anat Rec 241: 284287.
  • 39
    Ohlsson C, Nilsson A, Swolin D, Isaksson OG, Lindahl A 1993 Establishment of a growth hormone responsive chondrogenic cell line from fetal rat tibia. Mol Cell Endocrinol 91: 167175.
  • 40
    Gouveia CH, Jorgetti V, Bianco AC 1997 Effects of thyroid hormone administration and estrogen deficiency on bone mass of female rats. J Bone Miner Res 12: 20982107.
  • 41
    Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2: 595610.
  • 42
    Kielty CM, Kwan AP, Holmes DF, Schor SL, Grant ME 1985 Type X collagen, a product of hypertrophic chondrocytes. Biochem J 227: 545554.
  • 43
    Miki N, Ono M, Hizuka N, Aoki T, Demura H 1992 Thyroid hormone modulation of the hypothalamic growth hormone (GH)-releasing factor-pituitary GH axis in the rat. J Clin Invest 90: 113120.
  • 44
    Sjogren K, Bohlooly YM, Olsson B, Coschigano K, Tornell J, Mohan S, Isaksson OG, Baumann G, Kopchick J, Ohlsson C 2000 Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor−/− mice. Biochem Biophys Res Commun 267: 603608.
  • 45
    Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75: 5972.
  • 46
    Ishikawa Y, Genge BR, Wuthier RE, Wu LN 1998 Thyroid hormone inhibits growth and stimulates terminal differentiation of epiphyseal growth plate chondrocytes. J Bone Miner Res 13: 13981411.
  • 47
    Yakar S, Rosen CJ, Beamer WG, Ackert-Bicknell CL, Wu Y, Liu JL, Ooi GT, Setser J, Frystyk J, Boisclair YR, LeRoith D 2002 Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest 110: 771781.
  • 48
    Thorngren KG, Hansson LI 1973 Effect of thyroxine and growth hormone on longitudinal bone growth in the hypophysectomized rat. Acta Endocrinol (Copenh) 74: 2440.
  • 49
    Ray RD, Asling CW, Walker DG, Simpson ME, Li CH, Evans HM 1954 Growth and differentiation of the skeleton in thyroidectomized-hypophysectomized rats treated with thyroxin, growth hormone, and combination. J Bone Joint Surg Am 36: 94103.
  • 50
    Thorngren KG, Hansson LI 1974 Bioassay of growth hormone. II. Determination of longitudinal bone growth with tetracycline in thyroxine-treated hypophysectomized rats. Acta Endocrinol (Copenh) 75: 669682.
  • 51
    Gouveia CH, Schultz JJ, Bianco AC, Brent GA 2001 Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms. J Endocrinol 170: 667675.