SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Eisman JA 1999 Genetics of osteoporosis. Endocr Rev 20: 788804.
  • 2
    Riis BJ, Hansen MA, Jensen AM, Overgaard K, Christiansen C 1996 Low bone mass and fast rate of bone loss at menopause: Equal risk factors for future fracture: A 15-year follow-up study. Bone 19: 912.
  • 3
    Garnero P, Hausherr E, Chapuy MC, Marcelli C, Grandjean H, Muller C, Cormier C, Breart G, Meunier PJ, Delmas PD 1996 Markers of bone resorption predict hip fracture in elderly women: The EPIDOS Prospective Study. J Bone Miner Res 11: 15311538.
  • 4
    Riggs BL, Khosla S, Melton LJ III 2002 Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev 23: 279302.
  • 5
    Geusens P, Dequeker J, Verstraeten A, Nijs J 1986 Age-, sex-, and menopause-related changes of vertebral and peripheral bone: Population study using dual and single photon absorptiometry and radiogrammetry. J Nucl Med 27: 15401549.
  • 6
    Riggs BL, Wahner HW, Melton LJ III, Richelson LS, Judd HL, Offord KP 1986 Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause. J Clin Invest 77: 14871491.
  • 7
    Harris S, Dawson-Hughes B 1992 Rates of change in bone mineral density of the spine, heel, femoral neck and radius in healthy postmenopausal women. Bone Miner 17: 8795.
  • 8
    Pouilles JM, Tremollieres F, Ribot C 1995 Effect of menopause on femoral and vertebral bone loss. J Bone Miner Res 10: 15311536.
  • 9
    Guthrie JR, Ebeling PR, Hopper JL, Barrett-Connor E, Dennerstein L, Dudley EC, Burger HG, Wark JD 1998 A prospective study of bone loss in menopausal Australian-born women. Osteoporos Int 8: 282290.
  • 10
    Radspieler H, Dambacher MA, Kissling R, Neff M 2000 Is the amount of trabecular bone-loss dependent on bone mineral density? A study performed by three centres of osteoporosis using high resolution peripheral quantitative computed tomography. Eur J Med Res 5: 3239.
  • 11
    Christiansen C, Riis BJ, Rodbro P 1987 Prediction of rapid bone loss in postmenopausal women. Lancet 1: 11051108.
  • 12
    Dambacher MA, Kranich M, Schacht E, Neff M 1997 Can the fast bone loss in osteoporotic and osteopenic patients be stopped with active vitamin D metabolites? Calcif Tissue Int 60: 115118.
  • 13
    Riggs BL, Khosla S, Atkinson EJ, Dunstan CR, Melton LJ III 2003 Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency. Osteoporos Int 14: 728733.
  • 14
    Yoshimura N, Takijiri T, Kinoshita H, Danjoh S, Kasamatsu T, Morioka S, Sakata K, Hashimoto T, Takeshita T 2004 Characteristics and course of bone mineral densities among fast bone losers in a rural Japanese community: The Miyama Study. Osteoporos Int 15: 139144.
  • 15
    Riggs BL, Khosla S, Melton LJ III 2001 The type I/type II model for involutional osteoporosis. In: MarcusR, FeldmanD, KelseyJ (eds.) Osteoporosis, 2nd ed., vol. 2. Academic Press, San Diego, CA, USA, pp. 4958.
  • 16
    Peacock M, Turner CH, Econs MJ, Foroud T 2002 Genetics of osteoporosis. Endocr Rev 23: 303326.
  • 17
    Karasik D, Ginsburg E, Livshits G, Pavlovsky O, Kobyliansky E 2000 Evidence of major gene control of cortical bone loss in humans. Genet Epidemiol 19: 410421.
  • 18
    Keen RW, Woodford-Richens KL, Lanchbury JS, Spector TD 1998 Allelic variation at the interleukin-1 receptor antagonist gene is associated with early postmenopausal bone loss at the spine. Bone 23: 367371.
  • 19
    Salmen T, Heikkinen AM, Mahonen A, Kroger H, Komulainen M, Saarikoski S, Honkanen R, Maenpaa PH 2000 Early postmenopausal bone loss is associated with PvuII estrogen receptor gene polymorphism in Finnish women: Effect of hormone replacement therapy. J Bone Miner Res 15: 315321.
  • 20
    Ferrari SL, Garnero P, Emond S, Montgomery H, Humphries SE, Greenspan SL 2001 A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women. Arthritis Rheum 44: 196201.
  • 21
    Moffett SP, Zmuda JM, Cauley JA, Stone KL, Nevitt MC, Ensrud KE, Hillier TA, Hochberg MC, Joslyn G, Morin P, Cummings SR 2004 Association of the G-174C variant in the interleukin-6 promoter region with bone loss and fracture risk in older women. J Bone Miner Res 19: 16121618.
  • 22
    Tofteng CL, Kindmark A, Brandstrom H, Abrahamsen B, Petersen S, Stiger F, Stilgren LS, Jensen JE, Vestergaard P, Langdahl BL, Mosekilde L 2004 Polymorphisms in the CYP19 and AR genes-relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy: The Danish Osteoporosis Prevention Study. Calcif Tissue Int 74: 2534.
  • 23
    Khosla S, Riggs BL, Atkinson EJ, Oberg AL, Mavilia C, Del Monte F, Melton LJ III, Brandi ML 2004 Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men. J Clin Endocrinol Metab 89: 18081816.
  • 24
    Ioannidis JP, Ralston SH, Bennett ST, Brandi ML, Grinberg D, Karassa FB, Langdahl B, van Meurs JB, Mosekilde L, Scollen S, Albagha OM, Bustamante M, Carey AH, Dunning AM, Enjuanes A, van Leeuwen JP, Mavilia C, Masi L, McGuigan FE, Nogues X, Pols HA, Reid DM, Schuit SC, Sherlock RE, Uitterlinden AG 2004 Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes. JAMA 292: 21052114.
  • 25
    Hernandez ER, Revilla M, Seco-Durban C, Villa LF, Cortes J, Rico H 1997 Heterogeneity of trabecular and cortical postmenopausal bone loss: A longitudinal study with pQCT. Bone 20: 283287.
  • 26
    Beamer WG, Donahue LR, Rosen CJ, Baylink DJ 1996 Genetic variability in adult bone density among inbred strains of mice. Bone 18: 397403.
  • 27
    Klein RF, Mitchell SR, Phillips TJ, Belknap JK, Orwoll ES 1998 Quantitative trait loci affecting peak bone mineral density in mice. J Bone Miner Res 13: 16481656.
  • 28
    Turner CH, Hsieh YF, Muller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG 2000 Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Miner Res 15: 11261131.
  • 29
    Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ 2001 Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res 16: 11951206.
  • 30
    Li X, Masinde G, Gu W, Wergedal J, Mohan S, Baylink DJ 2002 Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: Single QTL effects, epistasis, and pleiotropy. Genomics 79: 734740.
  • 31
    Jepsen KJ, Akkus OJ, Majeska RJ, Nadeau JH 2003 Hierarchical relationship between bone traits and mechanical properties in inbred mice. Mamm Genome 14: 97104.
  • 32
    Judex S, Garman R, Squire M, Donahue LR, Rubin C 2004 Genetically based influences on the site-specific regulation of trabecular and cortical bone morphology. J Bone Miner Res 19: 600606.
  • 33
    Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill GA, Muller R, Beamer WG 2004 Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res 19: 587599.
  • 34
    Akhter MP, Cullen DM, Pedersen EA, Kimmel DB, Recker RR 1998 Bone response to in vivo mechanical loading in two breeds of mice. Calcif Tissue Int 63: 442449.
  • 35
    Kodama Y, Dimai HP, Wergedal J, Sheng M, Malpe R, Kutilek S, Beamer W, Donahue LR, Rosen C, Baylink DJ, Farley J 1999 Cortical tibial bone volume in two strains of mice: Effects of sciatic neurectomy and genetic regulation of bone response to mechanical loading. Bone 25: 183190.
  • 36
    Kodama Y, Umemura Y, Nagasawa S, Beamer WG, Donahue LR, Rosen CR, Baylink DJ, Farley JR 2000 Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL/6J mice but not in C3H/Hej mice. Calcif Tissue Int 66: 298306.
  • 37
    Robling AG, Turner CH 2002 Mechanotransduction in bone: Genetic effects on mechanosensitivity in mice. Bone 31: 562569.
  • 38
    Amblard D, Lafage-Proust MH, Laib A, Thomas T, Ruegsegger P, Alexandre C, Vico L 2003 Tail suspension induces bone loss in skeletally mature mice in the C57BL/6J strain but not in the C3H/HeJ strain. J Bone Miner Res 18: 561569.
  • 39
    Judex S, Garman R, Squire M, Busa B, Donahue LR, Rubin C 2004 Genetically linked site-specificity of disuse osteoporosis. J Bone Miner Res 19: 607613.
  • 40
    Hildebrand TPR 1997 A new method for the model independent assessment of thickness in three-dimensional images. J Microsc 185: 6775.
  • 41
    Hildebrand T, Rüesegger P 1997 Quantification of bone microarchitecture with the structure model index. Comput Methods Biomech Biomed Engin 1: 1523.
  • 42
    Harris S, Dallal G, Dawson-Hughes B 1992 Influence of body weight on rates of change in bone density of the spine, hip, and radius in postmenopausal women. Calcif Tissue Int 50: 1923.
  • 43
    Bainbridge KE, Sowers M, Lin X, Harlow SD 2004 Risk factors for low bone mineral density and the 6-year rate of bone loss among premenopausal and perimenopausal women. Osteoporos Int 15: 439446.
  • 44
    Syed F, Khosla S 2005 Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 328: 688696.