The authors have no conflict of interest.
Association of Amount of Physical Activity With Cortical Bone Size and Trabecular Volumetric BMD in Young Adult Men: The GOOD Study†
Version of Record online: 18 JUL 2005
Copyright © 2005 ASBMR
Journal of Bone and Mineral Research
Volume 20, Issue 11, pages 1936–1943, November 2005
How to Cite
Lorentzon, M., Mellström, D. and Ohlsson, C. (2005), Association of Amount of Physical Activity With Cortical Bone Size and Trabecular Volumetric BMD in Young Adult Men: The GOOD Study. J Bone Miner Res, 20: 1936–1943. doi: 10.1359/JBMR.050709
- Issue online: 4 DEC 2009
- Version of Record online: 18 JUL 2005
- Manuscript Accepted: 13 JUL 2005
- Manuscript Revised: 15 MAY 2005
- Manuscript Received: 21 MAR 2005
- physical activity;
In this population-based study, amount of PA was associated with cortical bone size (increased thickness and periosteal circumference) and trabecular vBMD, but not with cortical vBMD or length of the long bones in young men. The lowest effective amount of PA was ≥4 h/week.
Introduction: Physical activity (PA) is believed to have positive effects on the skeleton and possibly help in preventing the occurrence of osteoporosis. Neither the lowest effective amount of PA needed to induce an osteogenic response nor its effect on the BMD and size of the different bone compartments (i.e., trabecular and cortical bone) has yet been clarified.
Materials and Methods: In this population-based study, we investigated the amount of all types of PA in relation to areal BMD (aBMD), trabecular and cortical volumetric BMD (vBMD), and cortical bone size in 1068 men (age, 18.9 ± 0.02 years), included in the Gothenburg Osteoporosis and Obesity Determinants (GOOD) study. aBMD was measured by DXA, whereas cortical and trabecular vBMD and bone size were measured by pQCT.
Results and Conclusions: The amount of PA was associated with aBMD of the total body, radius, femoral neck, and lumbar spine, as well as with cortical bone size (increased thickness and periosteal circumference) and trabecular vBMD, but not with cortical vBMD or length of the long bones. The lowest effective amount of PA was ≥4 h/week. aBMD, cortical bone size, and trabecular vBMD were higher in subjects who started their training before age 13 than in subjects who started their training later in life. Our data indicate that ≥4 h/week of PA is required to increase bone mass in young men and that exercise before and during the pubertal growth is of importance. These findings suggest that PA is imperative for the augmentation of cortical bone size and trabecular vBMD but does not affect the cortical vBMD in young men.