SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Kaplan FS, Shore EM, Connor JM 2002 Fibrodysplasia ossificans progressiva (FOP). RoyceP, SteinmannB (eds.) Connective Tissue and Its Heritable Disorders, 2nd ed. Wiley-Liss, New York, NY, USA, 827840.
  • 2
    Kaplan FS, Shore EM, Zasloff MA 1996 Fibrodysplasia ossificans progressiva: Searching for the skeleton key. Calcif Tissue Int 59: 7578.
  • 3
    Kaplan FS, Tabas JA, Gannon FH, Finkel G, Hahn GV, Zasloff MA 1993 The histopathology of fibrodysplasia ossificans progressiva. An endochondral process. J Bone Joint Surg Am 75: 220230.
  • 4
    Gannon FH, Valentine BA, Shore EM, Zasloff MA, Kaplan FS 1998 Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva. Clin Orthop 346: 1925.
  • 5
    Cohen RB, Hahn GV, Tabas JA, Peeper J, Levitz CL, Sando A, Sando N, Zasloff M, Kaplan FS 1993 The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients. J Bone Joint Surg Am 75: 215219.
  • 6
    Connor JM, Evans DAP 1982 Fibrodysplasia ossificans progressiva. The clinical features and natural history of 34 patients. J Bone Joint Surg Br 64: 7683.
  • 7
    Lanchoney TF, Cohen RB, Rocke DM, Zasloff MA, Kaplan FS 1995 Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva. J Pediatr 126: 762764.
  • 8
    Luchetti W, Cohen RB, Hahn GV, Rocke DM, Helpin M, Zasloff M, Kaplan FS 1996 Severe restriction in jaw movement after routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81: 2125.
  • 9
    Glaser DL, Rocke DM, Kaplan FS 1998 Catastrophic falls in patients who have fibrodysplasia ossificans progressiva. Clin Orthop 346: 110116.
  • 10
    Kaplan FS, McCluskey W, Hahn G, Tabas JA, Muenke M, Zasloff MA 1993 Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family. J Bone Joint Surg Am 75: 12141220.
  • 11
    Feldman G, Li M, Martin S, Urbanek M, Urtizberea JA, Fardeau M, LeMerrer M, Connor JM, Triffitt J, Smith R, Muenke M, Kaplan FS, Shore EM 2000 Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31. Am J Hum Genet 66: 128135.
  • 12
    Xu MQ, Feldman G, Le Merrer M, Shugart YY, Glaser D, Urtizberea JA, Fardeau M, Connor JM, Triffitt J, Smith R, Shore EM, Kaplan FS 2000 Linkage exclusion and mutational analysis of the noggin gene in patients with fibrodysplasia ossificans progressiva. Clin Genet 58: 291298.
  • 13
    Xu MQ, Shore EM 1998 Mutational screening of the bone morphogenetic protein 4 gene in a family with fibrodysplasia ossificans progressive. Clin Orthop 346: 5358.
  • 14
    Shafritz AB, Shore EM, Gannon FH, Zasloff MA, Taub R, Muenke M, Kaplan FS 1996 Over-expression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N Engl J Med 335: 555561.
  • 15
    Gannon FH, Kaplan FS, Olmsted E, Finkel GC, Zasloff M, Shore EM 1997 Bone morphogenetic protein (BMP) 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva. Hum Pathol 28: 339343.
  • 16
    Olmsted EA, Kaplan FS, Shore EM 2003 Bone morphogenetic protein-4 regulation in fibrodysplasia ossificans progressiva. Clin Orthop 408: 331343.
  • 17
    de la Peña LS, Billings PC, Fiori JL, Ahn JA, Kaplan FS, Shore EM 2005 Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA. J Bone Miner Res 20: 11681176.
  • 18
    Sandhu HS, Khan SN 2002 Animal models for preclinical assessment of bone morphogenetic proteins in the spine. Spine 27: S32S38.
  • 19
    Seeherman H, Wozney J, Li R 2002 Bone morphogenetic protein delivery systems. Spine 27: S16S23.
  • 20
    Urist MR 1965 Bone formation by autoinduction. Science 150: 893899.
  • 21
    Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA 1988 Novel regulators of bone formation: Molecular clones and activities. Science 242: 15281534.
  • 22
    Kan L, Hu M, Gomes WA, Kessler JA 2004 Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressive (FOP)-like phenotype. Am J Pathol 165: 11071115.
  • 23
    Hoffmann A, Gross G 2001 BMP signaling pathways in cartilage and bone formation. Crit Rev Eukaryot Gene Expr 11: 2345.
  • 24
    Glaser DL, Economides AN, Wang L, Liu X, Kimble RD, Fandl JP, Wilson JM, Stahl N, Kaplan FS, Shore EM 2003 In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. J Bone Joint Surg Am 85: 23322342.
  • 25
    Massagué J, Blain SW, Lo RS 2000 TGFbeta signaling ingrowth control, cancer, and heritable disorders. Cell 103: 295309.
  • 26
    Canalis E, Economides AN, Gazzerro E 2003 Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr Rev 24: 218235.
  • 27
    Shi Y, Massague J 2003 Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685700.
  • 28
    Wrana JL, Attisano L, Wieser R, Ventura F, Massague J 1994 Mechanism of activation of the TGF-beta receptor. Nature 370: 341347.
  • 29
    Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI, Knaus P 2000 Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell 11: 10231035.
  • 30
    von Bubnoff A, Cho KW 2001 Intracellular BMP signaling regulation in vertebrates: Pathway or network? Dev Biol 239: 114.
  • 31
    Derynck R, Zhang YE 2003 Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425: 577584.
  • 32
    Attisano L, Wrana JL 2000 Smads as transcriptional comodulators. Curr Opin Cell Biol 12: 235243.
  • 33
    Tsai PT, Lee RA, Wu H 2003 BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis. Blood 102: 39473953.
  • 34
    Bhardwaj G, Murdoch B, Wu D 2001 Sonic hedgehog induces the proliferation of primary human hematopoietic cells via BMP regulation. Nat Immunol 2: 172180.
  • 35
    Ishisaki A, Yamato K, Hashimoto S, Nakao A, Tamaki K, Nonaka K, ten Dijke P, Sugino H, Nishihara T 1999 Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein and activin-mediated growth arrest and apoptosis in B cells. J Biol Chem 247: 1363713642.
  • 36
    Althini S, Usoskin D, Kylberg A, ten Dijke P, Ebendal T 2003 Bone Morphogenetic protein signaling in NGF-stimulated PC12 cells. Biochem Biophys Res Commun 307: 632639.
  • 37
    Korchynskyi O, ten Dijke P 2002 Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 277: 48834891.
  • 38
    Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Niederwieser D, Harris AL 2005 Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. J Cancer Res Clin Oncol 1: 110.
  • 39
    Brugger SM, Merrill AE, Torres-Vazquez J, Wu N, Ting MC, Cho JY, Dobias SL, Yi SE, Lyons K, Bell JR, Arora K, Warrior R, Maxson R 2004 A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos. Development 131: 51535165.
  • 40
    Ahn J, de Serrano la Peña L, Shore EM, Kaplan FS 2003 Paresis of a bone morphogenetic protein antagonist response in a genetic disorder of heterotopic skeletogenesis. J Bone Joint Surg Am 85: 667674.
  • 41
    Norton JD, Deed RW, Craggs G, Sablitzky F 1998 Id helix-loop-helix proteins in cell growth and differentiation. Trends Cell Biol 8: 5865.
  • 42
    Yan W, Young AZ, Soares VC, Kelley R, Benezra R, Zhuang Y 1997 High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol Cell Biol 17: 73177327.
  • 43
    Deed RW, Jasiok M, Norton JD 1998 Lymphoid-specific expression of the Id3 gene in hematopoietic cells. Selective antagonism of E2A basic helix-loop-helix protein associated with Id3-induced differentiation of erythroleukemia cells. J Biol Chem 273: 82788286.
  • 44
    Ogata T, Wozney JM, Benezra R, Noda M 1993 Bone morphogenetic protein 2 transiently enhances expression of a gene, Id (inhibitor of differentiation), encoding a helix-loop-helix molecule in osteoblast like cells. Proc Natl Acad Sci USA 90: 92199222.
  • 45
    Neuman T, Kenn A, Zuber MX, Kristiansson GI, Gruss P, Nomes HO 1993 Neuronal expression of regulatory helix-loop-helix factor Id2 gene in mouse. Dev Biol 160: 186195.
  • 46
    Voronova A, Lee F 1994 The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation. Proc Natl Acad Sci USA 91: 59525956.
  • 47
    Heemskerk MH, Blom B, Nolan G, Stegmann AP, Bakker AQ, Weijer K, Res PC, Spits H 1997 Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J Exp Med 186: 15971602.
  • 48
    Martinsen BJ, Bronner-Fraser M 1998 Neural crest specification regulated by the helix-loop-helix repressor Id2. Science 281: 988991.
  • 49
    Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T 1994 Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127: 17551766.
  • 50
    Maeda Y, Tsuji K, Nifuji A, Noda M 2004 Inhibitory helix-loop-helix transcription factors Id1/Id3 promote bone formation in vivo. J Cell Biochem 93: 337344.
  • 51
    Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R, Bader BL, Hynes RO, Zhuang Y, Mandova K, Benezra R 1999 Id1 and Id3 are required for neurogenesis, angiogenesis, and vascularization of tumour xenografts. Nature 401: 670677.
  • 52
    Davidson D 1995 The function and evolution of Msx genes: Pointers and paradoxes. Trends Genet 11: 405411.
  • 53
    Jabs EW, Muller U, Li X, Ma L, Luo W, Haworth IS, Klisak I, Sparkes R, Warman ML, Mulliken JB 1993 A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell 75: 443450.
  • 54
    Meyers GA, Orlow SJ, Munro IR, Przylepa KA, Jabs EW 1995 Fibroblast growth factor receptor 3 (FGFR3) transmembrane mutation in Crouzon syndrome with acanthosis nigricans. Nat Genet 11: 462464.