• 1
    Ismail AA, Cooper C, Felsenberg D, Varlow J, Kanis JA, Silman AJ, O'Neill TW 1999 Number and type of vertebral deformities: Epidemiological characteristics and relation to back pain and height loss. European Vertebral Osteoporosis Study Group. Osteoporos Int 9: 206213.
  • 2
    Roy DK, O'Neill TW, Finn JD, Lunt M, Silman AJ, Felsenberg D, Armbrecht G, Banzer D, Benevolenskaya LI, Bhalla A, Bruges Armas J, Cannata JB, Cooper C, Dequeker J, Diaz MN, Eastell R, Yershova OB, Felsch B, Gowin W, Havelka S, Hoszowski K, Ismail AA, Jajic I, Janott I, Johnell O, Kanis JA, Kragl G, Lopez Vaz A, Lorenc R, Lyritis G, Masaryk P, Matthis C, Miazgowski T, Gennari C, Pols HA, Poor G, Raspe HH, Reid DM, Reisinger W, Scheidt-Nave C, Stepan JJ, Todd CJ, Weber K, Woolf AD, Reeve J 2003 Determinants of incident vertebral fracture in men and women: Results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int 14: 1926.
  • 3
    U.S. Department of Health and Human Services 2004 Bone Health and Osteoporosis: A Report of the Surgeon General. U.S. Department of Health and Human Services, Office of the Surgeon General, Rockville, MD, USA.
  • 4
    Nevitt MC, Cummings SR, Stone KL, Palermo L, Black DM, Bauer DC, Genant HK, Hochberg MC, Ensrud KE, Hillier TA, Cauley JA 2005 Risk factors for a first-incident radiographic vertebral fracture in women > or = 65 years of age: The study of osteoporotic fractures. J Bone Miner Res 20: 131140.
  • 5
    Hayes WC, Piazza SJ, Zysset PK 1991 Biomechanics of fracture risk prediction of the hip and spine by quantitative computed tomography. Radiol Clin North Am 29: 118.
  • 6
    Bouxsein M 2001 Biomechanics of age-related fractures. MarcusR, FeldmanD, KelseyJ (eds.) Osteoporosis, 2nd ed. Academic Press, San Diego, CA, USA, 509534.
  • 7
    Riggs BL, Melton LJ III, Robb RA, Camp JJ, Atkinson EJ, Oberg AL, Rouleau PA, McCollough CH, Khosla S, Bouxsein ML 2006 Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res 21: 315323.
  • 8
    Ferrar L, Jiang G, Adams J, Eastell R 2005 Identification of vertebral fractures: An update. Osteoporos Int 16: 717728.
  • 9
    Melton LJ, Wenger DE, Atkinson EJ, Achenbach SJ, Berquist TH, Riggs BL, Jiang G, Eastell R 2006 Influence of baseline deformity definition on subsequent vertebral fracture risk in postmenopausal women. Osteoporos Int 17: 978985.
  • 10
    Cooper C, Atkinson E, O'Fallon W, Melton L 1992 Incidence of clinically diagnosed vertebral fractures: A population-based study in Rochester, Minnesota, 1985-1989. J Bone Miner Res 7: 221227.
  • 11
    Nevitt MC, Ettinger B, Black DM, Stone K, Jamal SA, Ensrud K, Segal M, Genant HK, Cummings SR 1998 The association of radiographically detected vertebral fractures with back pain and function: A prospective study. Ann Intern Med 128: 793800.
  • 12
    Delmas PD, van de Langerijt L, Watts NB, Eastell R, Genant H, Grauer A, Cahall DL 2005 Underdiagnosis of vertebral fractures is a worldwide problem: The IMPACT study. J Bone Miner Res 20: 557563.
  • 13
    Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA III, Berger M 2000 Patients with prior fractures have an increased risk of future fractures: A summary of the literature and statistical synthesis. J Bone Miner Res 15: 721739.
  • 14
    Delmas PD, Genant HK, Crans GG, Stock JL, Wong M, Siris E, Adachi JD 2003 Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: Results from the MORE trial. Bone 33: 522532.
  • 15
    Myers ER, Wilson SE 1997 Biomechanics of osteoporosis and vertebral fracture. Spine 22(24 Suppl): 25S31S.
  • 16
    Moro M, Hecker AT, Bouxsein ML, Myers ER 1995 Failure load of thoracic vertebrae correlates with lumbar bone mineral density measured by DXA. Calcif Tissue Int 56: 206209.
  • 17
    Wilson S 1994 Development of a Model to Predict the Compressive Forces on the Spine Associated With Age-Related Vertebral Fractures. Massachusetts Institute of Technology, Cambridge, MA, USA.
  • 18
    Duan Y, Seeman E, Turner CH 2001 The biomechanical basis of vertebral body fragility in men and women. J Bone Miner Res 16: 22762283.
  • 19
    Duan Y, Wang XF, Evans A, Seeman E 2005 Structural and biomechanical basis of racial and sex differences in vertebral fragility in Chinese and Caucasians. Bone 36: 987998.
  • 20
    Riggs BL, Melton Iii LJ III, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S 2004 Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res 19: 19451954.
    Direct Link:
  • 21
    Khosla S, Melton LJ III, Achenbach SJ, Oberg AL, Riggs BL 2006 Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men. J Clin Endocrinol Metab 91: 885891.
  • 22
    Camp JJ, Kaworski RA, Stacy MC, Atkinson EJ, Khosla S, Melton LJ III, Riggs BL, Robb RA 2004 A system for the analysis of whole-bone strength from helical CT images. Proc SPIE 5369: 7488.
  • 23
    Geer JM 2001 Mechanics of Materials, 5th ed. Brooks/Cole, Pacific Grove, CA, USA.
  • 24
    Keaveny TM, Morgan EF, Niebur GL, Yeh OC 2001 Biomechanics of trabecular bone. Annu Rev Biomed Eng 3: 307333.
  • 25
    Morgan EF, Keaveny TM 2001 Dependence of yield strain of human trabecular bone on anatomic site. J Biomech 34: 569577.
  • 26
    Whealan KM, Kwak SD, Tedrow JR, Inoue K, Snyder BD 2000 Noninvasive imaging predicts failure load of the spine with simulated osteolytic defects. J Bone Joint Surg Am 82: 12401251.
  • 27
    Snyder BD, Hauser-Kara DA, Hipp JA, Zurakowski D, Hecht AC, Gebhardt MC 2006 Predicting fracture through benign skeletal lesions with quantitative computed tomography. J Bone Joint Surg Am 88: 5570.
  • 28
    Crawford RP, Cann CE, Keaveny TM 2003 Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography. Bone 33: 744750.
  • 29
    Kopperdahl DL, Morgan EF, Keaveny TM 2002 Quantitative computed tomography estimates of the mechanical properties of human vertebral trabecular bone. J Orthop Res 20: 801805.
  • 30
    Schultz AB, Andersson GBJ 1981 Analysis of loads on the lumbar spine. Spine 6: 7682.
  • 31
    Schultz A, Andersson G, Ortengren R, Haderspeck K, Nachemson A 1982 Loads on the lumbar spine. Validation of a biomechanical analysis by measurements of intradiscal pressures and myoelectric signals. J Bone Joint Surg Am 64: 713720.
  • 32
    Moga PJ, Erig M, Chaffin DB, Nussbaum MA 1993 Torso muscle moment arms at intervertebral levels T10 through L5 from CT scans on eleven male and eight female subjects. Spine 18: 23052309.
  • 33
    Naval Biodynamics Laboratory 1988 Anthropometry and Mass Distribtuion for Human Analogues, volume I: Military Male Aviators. Naval Medical Research and Development Command, New Orleans, LA, USA.
  • 34
    Nachemson A, Elfström G 1970 Intravital dynamic pressure measurements in lumbar discs. Scand J Rehabil Med Suppl 1: 340.
  • 35
    Melton LJ III 1996 History of the Rochester Epidemiology Project. Mayo Clin Proc 71: 266274.
  • 36
    Venables W, Ripley B 1994 Modern Applied Statistics with S-Plus. Springer-Verlag, New York, NY, USA.
  • 37
    Myers E, Wilson S 1997 Biomechanics of osteoporosis and vertebral fractures. Spine 22: 25S31S.
  • 38
    Cheng XG, Lowet G, Boonen S, Nicholson PH, Van der Perre G, Dequeker J 1998 Prediction of vertebral and femoral strength in vitro by bone mineral density measured at different skeletal sites. J Bone Miner Res 13: 14391443.
  • 39
    Lochmuller EM, Burklein D, Kuhn V, Glaser C, Muller R, Gluer CC, Eckstein F 2002 Mechanical strength of the thoracolumbar spine in the elderly: Prediction from in situ dual-energy X-ray absorptiometry, quantitative computed tomography (QCT), upper and lower limb peripheral QCT, and quantitative ultrasound. Bone 31: 7784.
  • 40
    McGill SM, Norman RW 1985 Dynamically and statically determined low back moments during lifting. J Biomech 18: 877885.
  • 41
    Adams MA, Dolan P 2005 Spine biomechanics. J Biomech 38: 19721983.
  • 42
    Brown SH, Potvin JR 2005 Constraining spine stability levels in an optimization model leads to the prediction of trunk muscle cocontraction and improved spine compression force estimates. J Biomech 38: 745754.
  • 43
    Potvin JR, Brown SH 2005 An equation to calculate individual muscle contributions to joint stability. J Biomech 38: 973980.
  • 44
    Guzik DC, Keller TS, Szpalski M, Park JH, Spengler DM 1996 A biomechanical model of the lumbar spine during upright isometric flexion, extension, and lateral bending. Spine 21: 427433.
  • 45
    Wood S, Pearsall DJ, Ross R, Reid JG 1996 Trunk muscle parameters determined from MRI for lean to obese males. Clin Biomech (Bristol, Avon) 11: 139144.
  • 46
    McGill SM 1997 The biomechanics of low back injury: Implications on current practice in industry and the clinic. J Biomech 30: 465475.
  • 47
    Hughes RE 2000 Effect of optimization criterion on spinal force estimates during asymmetric lifting. J Biomech 33: 225229.
  • 48
    Duan Y, Duboeuf F, Munoz F, Delmas PD, Seeman E 2006 The fracture risk index and bone mineral density as predictors of vertebral structural failure. Osteoporos Int 17: 5460.