SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Niu T, Rosen CJ 2005 The insulin-like growth factor-I gene and osteoporosis: A critical appraisal. Gene 361: 3856.
  • 2
    Deng HW, Mahaney MC, Williams JT, Li J, Conway T, Davies KM, Li JL, Deng H, Recker RR 2002 Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet Epidemiol 22: 1225.
  • 3
    Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW 2005 Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int 16: 21132122.
  • 4
    Hsu YH, Niu T, Terwedow HA, Xu X, Feng Y, Li Z, Brain JD, Rosen CJ, Laird N, Xu X 2006 Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet 118: 568577.
  • 5
    O'Connell JR, Weeks DE 1998 PedCheck: A program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63: 259266.
  • 6
    Abecasis GR, Cherny SS, Cookson WO, Cardon LR 2002 Merlin—rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30: 97101.
  • 7
    Zhang K, Jin L 2003 HaploBlockFinder: Haplotype block analyses. Bioinformatics 19: 13001301.
  • 8
    Barrett JC, Fry B, Maller J, Daly MJ 2005 Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263265.
  • 9
    Horvath S, Xu X, Laird NM 2001 The family based association test method: Strategies for studying general genotype–phenotype associations. Eur J Hum Genet 9: 301306.
  • 10
    Laird NM, Horvath S, Xu X 2000 Implementing a unified approach to family-based tests of association. Genet Epidemiol 19(Suppl 1): S36S42.
  • 11
    Styrkarsdottir U, Cazier JB, Kong A, Rolfsson O, Larsen H, Bjarnadottir E, Johannsdottir VD, Sigurdardottir MS, Bagger Y, Christiansen C, Reynisdottir I, Grant SF, Jonasson K, Frigge ML, Gulcher JR, Sigurdsson G, Stefansson K 2003 Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biol 1: E69.
  • 12
    Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM 2004 Family-based tests for associating haplotypes with general phenotype data: Application to asthma genetics. Genet Epidemiol 26: 6169.
  • 13
    Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, Steel G, Nestadt G, Liang KY, Huganir RL, Valle D, Pulver AE 2005 Bipolar I Disorder and Schizophrenia: A 440-Single-Nucleotide Polymorphism Screen of 64 Candidate Genes among Ashkenazi Jewish Case-Parent Trios. Am J Hum Genet 77: 918936.
  • 14
    Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, Moore JH 2001 Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 69: 138147.
  • 15
    Moore JH 2004 Computational analysis of gene-gene interactions using multifactor dimensionality reduction. Expert Rev Mol Diagn 4: 795803.
  • 16
    Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D 2002 The structure of haplotype blocks in the human genome. Science 296: 22252229.
  • 17
    Nyholt DR 2004 A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74: 765769.
  • 18
    Fang Y, van Meurs JB, d'Alesio A, Jhamai M, Zhao H, Rivadeneira F, Hofman A, van Leeuwen JP, Jehan F, Pols HA, Uitterlinden AG 2005 Promoter and 3′-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: The rotterdam study. Am J Hum Genet 77: 807823.
  • 19
    Yanase T, Simpson ER, Waterman MR 1991 17 alpha-hydroxylase/17,20-lyase deficiency: From clinical investigation to molecular definition. Endocr Rev 12: 91108.
  • 20
    Yamada Y, Ando F, Shimokata H 2005 Association of polymorphisms in CYP17A1, MTP, and VLDLR with bone mineral density in community-dwelling Japanese women and men. Genomics 86: 7685.
  • 21
    Tofteng CL, Abrahamsen B, Jensen JE, Petersen S, Teilmann J, Kindmark A, Vestergaard P, Gram J, Langdahl BL, Mosekilde L 2004 Two single nucleotide polymorphisms in the CYP17 and COMT Genes–relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy. The Danish Osteoporosis Prevention Study. Calcif Tissue Int 75: 123132.
  • 22
    Lorentzon M, Swanson C, Eriksson AL, Mellstrom D, Ohlsson C 2006 Polymorphisms in the aromatase gene predict areal BMD as a result of affected cortical bone size: The GOOD Study. J Bone Miner Res 21: 332339.
  • 23
    Somner J, McLellan S, Cheung J, Mak YT, Frost ML, Knapp KM, Wierzbicki AS, Wheeler M, Fogelman I, Ralston SH, Hampson GN 2004 Polymorphisms in the P450 c17 (17-hydroxylase/17,20-Lyase) and P450 c19 (aromatase) genes: Association with serum sex steroid concentrations and bone mineral density in postmenopausal women. J Clin Endocrinol Metab 89: 344351.
  • 24
    Dick IM, Devine A, Prince RL 2005 Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older women. Am J Physiol Endocrinol Metab 288: E989E995.
  • 25
    Zarrabeitia MT, Hernandez JL, Valero C, Zarrabeitia AL, Garcia-Unzueta M, Amado JA, Gonzalez-Macias J, Riancho JA 2004 A common polymorphism in the 5′-untranslated region of the aromatase gene influences bone mass and fracture risk. Eur J Endocrinol 150: 699704.
  • 26
    Riancho JA, Zarrabeitia MT, Valero C, Sanudo C, Hernandez JL, Amado JA, Zarrabeitia A, Gonzalez-Macias J 2005 Aromatase gene and osteoporosis: Relationship of ten polymorphic loci with bone mineral density. Bone 36: 917925.
  • 27
    Al-oanzi ZH, Tuck SP, Varanasi SS, Raj N, Harrop JS, Summers GD, Cook DB, Francis RM, Datta HK 2004 (TAAA)(n)-Alu element polymorphism in vitamin D binding protein gene and its association with bone density and osteoporosis in men. J Bone Miner Res 19: S249.
  • 28
    Papiha SS, Allcroft LC, Kanan RM, Francis RM, Datta HK 1999 Vitamin D binding protein gene in male osteoporosis: Association of plasma DBP and bone mineral density with (TAAA)(n)-Alu polymorphism in DBP. Calcif Tissue Int 65: 262266.
  • 29
    Ferrari SL, Deutsch S, Choudhury U, Chevalley T, Bonjour JP, Dermitzakis ET, Rizzoli R, Antonarakis SE 2004 Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet 74: 866875.
  • 30
    Ferrari SL, Deutsch S, Baudoin C, Cohen-Solal M, Ostertag A, Antonarakis SE, Rizzoli R, de Vernejoul MC 2005 LRP5 gene polymorphisms and idiopathic osteoporosis in men. Bone 37: 770775.
  • 31
    Koller DL, Ichikawa S, Johnson ML, Lai D, Xuei X, Edenberg HJ, Conneally PM, Hui SL, Johnston CC, Peacock M, Foroud T, Econs MJ 2005 Contribution of the LRP5 gene to normal variation in peak BMD in women. J Bone Miner Res 20: 7580.
  • 32
    Koay MA, Woon PY, Zhang Y, Miles LJ, Duncan EL, Ralston SH, Compston JE, Cooper C, Keen R, Langdahl BL, MacLelland A, O'Riordan J, Pols HA, Reid DM, Uitterlinden AG, Wass JA, Brown MA 2004 Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res 19: 16191627.
  • 33
    Bollerslev J, Wilson SG, Dick IM, Islam FM, Ueland T, Palmer L, Devine A, Prince RL 2005 LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women. Bone 36: 599606.
  • 34
    Xu H, Zhao LJ, Lei SF, Li MX, Sun X, Deng FY, Jiang DK, Deng HW 2005 The (CA)n polymorphism of the TNFR2 gene is associated with peak bone density in Chinese nuclear families. J Hum Genet 50: 301304.
  • 35
    Spotila LD, Rodriguez H, Koch M, Tenenhouse HS, Tenenhouse A, Li H, Devoto M 2003 Association analysis of bone mineral density and single nucleotide polymorphisms in two candidate genes on chromosome 1p36. Calcif Tissue Int 73: 140146.
  • 36
    Tsai FJ, Chen WC, Chen HY, Tsai CH 2003 The ALUI calcitonin receptor gene polymorphism (TT) is associated with low bone mineral density and susceptibility to osteoporosis in postmenopausal women. Gynecol Obstet Invest 55: 8287.
  • 37
    Braga V, Sangalli A, Malerba G, Mottes M, Mirandola S, Gatti D, Rossini M, Zamboni M, Adami S 2002 Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men. Calcif Tissue Int 70: 457462.
  • 38
    Mizuguchi T, Furuta I, Watanabe Y, Tsukamoto K, Tomita H, Tsujihata M, Ohta T, Kishino T, Matsumoto N, Minakami H, Niikawa N, Yoshiura K 2004 LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J Hum Genet 49: 8086.
  • 39
    Ezura Y, Urano T, Nakajima T, Sudo Y, Yoshida H, Suzuki T, Hosoi T, Inoue S, Shiraki M, Emi M 2004 Association of single nucleotide polymorphisms in the low density lipoprotein receptor-related protein 5 gene (LRP5) with bone mineral density of adult women. J Bone Miner Res 19: S247.
  • 40
    Fitzpatrick LA, Buzas E, Gagne TJ, Nagy A, Horvath C, Ferencz V, Mester A, Kari B, Ruan M, Falus A, Barsony J 2003 Targeted deletion of histidine decarboxylase gene in mice increases bone formation and protects against ovariectomy-induced bone loss. Proc Natl Acad Sci USA 100: 60276032.
  • 41
    Graves L III, Stechschulte DJ, Morris DC, Lukert BP 1990 Inhibition of mediator release in systemic mastocytosis is associated with reversal of bone changes. J Bone Miner Res 5: 11131119.
  • 42
    Liu YZ, Dvornyk V, Lu Y, Shen H, Lappe JM, Recker RR, Deng HW 2005 A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J Biol Chem 280: 2901129016.
  • 43
    Klein RF, Allard J, Avnur Z, Nikolcheva T, Rotstein D, Carlos AS, Shea M, Waters RV, Belknap JK, Peltz G, Orwoll ES 2004 Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science 303: 229232.
  • 44
    Wennberg P, Nordstrom P, Lorentzon R, Lerner UH, Lorentzon M 2002 TNF-alpha gene polymorphism and plasma TNF-alpha levels are related to lumbar spine bone area in healthy female Caucasian adolescents. Eur J Endocrinol 146: 629634.
  • 45
    Fontova R, Gutierrez C, Vendrell J, Broch M, Vendrell I, Simon I, Fernandez-Real JM, Richart C 2002 Bone mineral mass is associated with interleukin 1 receptor autoantigen and TNF-alpha gene polymorphisms in post-menopausal Mediterranean women. J Endocrinol Invest 25: 684690.
  • 46
    McLean RR, Karasik D, Selhub J, Tucker KL, Ordovas JM, Russo GT, Cupples LA, Jacques PF, Kiel DP 2004 Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status. J Bone Miner Res 19: 410418.
  • 47
    Kinyamu HK, Archer TK 2003 Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression. Mol Cell Biol 23: 58675881.
  • 48
    de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D 2005 Efficiency and power in genetic association studies. Nat Genet 37: 12171223.
  • 49
    Nguyen TV, Howard GM, Kelly PJ, Eisman JA 1998 Bone mass, lean mass, and fat mass: Same genes or same environments? Am J Epidemiol 147: 316.