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REFERENCES

  • 1
    Niu T, Rosen CJ 2005 The insulin-like growth factor-I gene and osteoporosis: A critical appraisal. Gene 361: 3856.
  • 2
    Deng HW, Mahaney MC, Williams JT, Li J, Conway T, Davies KM, Li JL, Deng H, Recker RR 2002 Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet Epidemiol 22: 1225.
  • 3
    Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP, He X 2000 LDL-receptor-related proteins in Wnt signal transduction. Nature 407: 530535.
  • 4
    Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K, Lifton RP 2002 High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 346: 15131521.
  • 5
    Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Juppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, Warman ML 2001 LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107: 513523.
  • 6
    Little RD, Carulli JP, Del Mastro RG, Dupuis J, Osborne M, Folz C, Manning SP, Swain PM, Zhao SC, Eustace B, Lappe MM, Spitzer L, Zweier S, Braunschweiger K, Benchekroun Y, Hu X, Adair R, Chee L, FitzGerald MG, Tulig C, Caruso A, Tzellas N, Bawa A, Franklin B, McGuire S, Nogues X, Gong G, Allen KM, Anisowicz A, Morales AJ, Lomedico PT, Recker SM, Van Eerdewegh P, Recker RR, Johnson ML 2002 A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 70: 1119.
  • 7
    Ferrari SL, Deutsch S, Choudhury U, Chevalley T, Bonjour JP, Dermitzakis ET, Rizzoli R, Antonarakis SE 2004 Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet 74: 866875.
  • 8
    Koay MA, Woon PY, Zhang Y, Miles LJ, Duncan EL, Ralston SH, Compston JE, Cooper C, Keen R, Langdahl BL, MacLelland A, O'Riordan J, Pols HA, Reid DM, Uitterlinden AG, Wass JA, Brown MA 2004 Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res 19: 16191627.
  • 9
    Koller DL, Ichikawa S, Johnson ML, Lai D, Xuei X, Edenberg HJ, Conneally PM, Hui SL, Johnston CC, Peacock M, Foroud T, Econs MJ 2005 Contribution of the LRP5 gene to normal variation in peak BMD in women. J Bone Miner Res 20: 7580.
  • 10
    Mizuguchi T, Furuta I, Watanabe Y, Tsukamoto K, Tomita H, Tsujihata M, Ohta T, Kishino T, Matsumoto N, Minakami H, Niikawa N, Yoshiura K 2004 LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J Hum Genet 49: 8086.
  • 11
    Urano T, Shiraki M, Ezura Y, Fujita M, Sekine E, Hoshino S, Hosoi T, Orimo H, Emi M, Ouchi Y, Inoue S 2004 Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density. J Bone Miner Metab 22: 341345.
  • 12
    van Meurs JB, Rivadeneira F, Jhamai M, Hugens W, Hofman A, van Leeuwen JP, Pols HA, Uitterlinden AG 2006 Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men. J Bone Miner Res 21: 141150.
  • 13
    Koh JM, Jung MH, Hong JS, Park HJ, Chang JS, Shin HD, Kim SY, Kim GS 2004 Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men. J Korean Med Sci 19: 407412.
  • 14
    Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW 2005 Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int 16: 21132122.
  • 15
    O'Connell JR, Weeks DE 1998 PedCheck: A program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63: 259266.
  • 16
    Abecasis GR, Cherny SS, Cookson WO, Cardon LR 2002 Merlin–rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30: 97101.
  • 17
    Liu K, Muse SV 2005 PowerMarker: An integrated analysis environment for genetic marker analysis. Bioinformatics 21: 21282129.
  • 18
    Barrett JC, Fry B, Maller J, Daly MJ 2005 Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263265.
  • 19
    Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D 2002 The structure of haplotype blocks in the human genome. Science 296: 22252229.
  • 20
    Pritchard JK, Stephens M, Rosenberg NA, Donnelly P 2000 Association mapping in structured populations. Am J Hum Genet 67: 170181.
  • 21
    Dudbridge F 2003 Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 25: 115121.
  • 22
    Nyholt DR 2004 A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74: 765769.
  • 23
    Almasy L, Blangero J 1998 Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62: 11981211.
  • 24
    Horvath S, Xu X, Laird NM 2001 The family based association test method: Strategies for studying general genotype–phenotype associations. Eur J Hum Genet 9: 301306.
  • 25
    Laird NM, Horvath S, Xu X 2000 Implementing a unified approach to family-based tests of association. Genet Epidemiol 19(Suppl 1): S36S42.
  • 26
    Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM 2004 Family-based tests for associating haplotypes with general phenotype data: Application to asthma genetics. Genet Epidemiol 26: 6169.
  • 27
    Twells RC, Mein CA, Phillips MS, Hess JF, Veijola R, Gilbey M, Bright M, Metzker M, Lie BA, Kingsnorth A, Gregory E, Nakagawa Y, Snook H, Wang WY, Masters J, Johnson G, Eaves I, Howson JM, Clayton D, Cordell HJ, Nutland S, Rance H, Carr P, Todd JA 2003 Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene. Genome Res 13: 845855.
  • 28
    Bollerslev J, Wilson SG, Dick IM, Islam FM, Ueland T, Palmer L, Devine A, Prince RL 2005 LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women. Bone 36: 599606.
  • 29
    Ferrari SL, Deutsch S, Baudoin C, Cohen-Solal M, Ostertag A, Antonarakis SE, Rizzoli R, de Vernejoul MC 2005 LRP5 gene polymorphisms and idiopathic osteoporosis in men. Bone 37: 770775.
  • 30
    Zhang ZL, Qin YJ, He JW, Huang QR, Li M, Hu YQ, Liu YJ 2005 Association of polymorphisms in low-density lipoprotein receptor-related protein 5 gene with bone mineral density in postmenopausal Chinese women. Acta Pharmacol Sin 26: 11111116.
  • 31
    Oakley JI, Moffett SP, Petro N, Cauley JA, Beck TJ, Bunker CH, Patrick AL, Wheeler VW, Ferrell RE, Zmuda JM 2004 LRP5 Amino Acid Substitutions: Differences in allele frequencies and association with Bone Density and Structure in Afro-Caribbean Men. J Bone Miner Res 19: S387.
  • 32
    Frazer KA, Pachter L, Poliakov A, Rubin EM, Dubchak I 2004 VISTA: Computational tools for comparative genomics. Nucleic Acids Res 32: W273W279.
  • 33
    Guo YF, Xiong DH, Shen H, Zhao LJ, Xiao P, Guo Y, Wang W, Yang TL, Robert RR, Deng HW 2006 Polymorphisms of the Low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study. J Med Genet 43: 798803.
  • 34
    Xiong DH, Shen H, Zhao LJ, Xiao P, Yang TL, Guo Y, Wang W, Guo YF, Liu YJ, Recker RR, Deng HW 2006 A Robust and Comprehensive Analysis of 20 Osteoporosis Candidate Genes by Very High-Density Single-Nucleotide Polymorphism Screen among 405 Caucasian Nuclear Families Identified Significant Association and Gene-Gene Interaction. J Bone Miner Res 21: 16781695.