• 1
    Karin M, Lawrence T, Nizet V 2006 Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer. Cell 124: 823835.
  • 2
    Modlin RL, Cheng G 2004 From plankton to pathogen recognition. Nat Med 10: 11731174.
  • 3
    Adams JS 2006 Vitamin D as a defensin. J Musculoskelet Neuron Interact. 6: 344346.
  • 4
    Sun J, Kong J, Duan Y, Szeto FL, Liao A, Madara JL, Li YC 2006 Increased NF-kappaB activity in fibroblasts lacking the vitamin D receptor. Am J Physiol Endocrinol Metab 29: E315E322.
  • 5
    Sadeghi K, Wessner B, Laggner U, Ploder M, Tamandl D, Friedl J, Zugel U, Steinmeyer A, Pollak A, Roth E, Boltz-Nitulescu G, Spittler A 2006 Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol 36: 361370.
  • 6
    Barnes PH, Modlin RL, Bikle DD, Adams JS 1989 Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis. J Clin Invest 83: 15271532.
  • 7
    Adams JS, Modlin RL, Diz MM, Barnes PH 1989 Potentiation of the macrophage 25-hydroxyvitamin D-1-hydroxylation reaction by human tuberculous pleural effusion fluid. J Clin Endocrinol Metab 69: 457460.
  • 8
    Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zugel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL 2006 Toll-like receptor triggering of a vitamin D–mediated human antimicrobial response. Science 24: 17701773.
  • 9
    White JH 2004 Profiling 1,25-dihydroxyvitamin D3-regulated gene expression by microarray analysis. J Steroid Biochem Mol Biol 89: 239244.
  • 10
    Gombart AF, Borregaard N, Koeffler HP 2005 Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J 19: 10671077.
  • 11
    Ren SY, Nguyen L, Adams JS, Hewison M 2005 Alternative splicing of the vitamin D-24-hydroxylase. J Biol Chem 280: 20602061.
  • 12
    Chen H, Hewison M, Adams JS 2006 Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: A novel response element binding protein. J Biol Chem 281: 3911439120.
  • 13
    Chen H, Hewison M, Hu B, Adams JS 2003 Heterogenous nuclear ribonucleoprotein (hnRNP) binding to hormone response elements: A cause of vitamin D resistance. Proc Natl Acad Sci USA 100: 61096114.
  • 14
    Nykjaer A, Dragun D, Walther D, Vorum H, Jacobsen C, Herz J, Melsen F, Christensen EI, Willnow TE 1999 An endocytic pathway essential for renal uptake and activation of the steroid 25(OH) vitamin D3. Cell 96: 507515.
  • 15
    Wu S, Ren S, Chen H, Chun RF, Gacad MA, Adams JS 2000 Intracellular vitamin D binding proteins: Novel facilitators of vitamin D-directed transactivation. Molec Endocrinol 14: 13871397.
  • 16
    Adams JS, Chen H, Chun R, Gacad MA, Encinas C, Ren S, Nguyen L, Wu S, Hewison M, Barsony J 2004 Response element binding proteins and intracellular vitamin D binding proteins: Novel regulators of vitamin D trafficking, action and metabolism. J Steroid Biochem Mol Biol 89-90: 461465.