• 1
    Yates AA, Schlicker SA, Suitor CW 1998 Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 98: 699706.
  • 2
    Munro I 2001 Derivation of tolerable upper intake levels of nutrients. Am J Clin Nutr 74: 865867.
  • 3
    Standing Committee on the Scientific Evaluation of Dietary Reference Intakes 1997 Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. National Academy Press, Washington, DC, USA.
  • 4
    Health and Consumer Protection Directorate General 2002 Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin D. European Commission, Brussels, Belgium.
  • 5
    Vieth R, Chan PC, MacFarlane GD 2001 Efficacy and safety of vitamin D(3) intake exceeding the lowest observed adverse effect level. Am J Clin Nutr 73: 288294.
  • 6
    Shephard RM, DeLuca HF 1980 Plasma concentrations of vitamin D3 and its metabolites in the rat as influenced by vitamin D3 or 25-hydroxyvitamin D3 intakes. Arch Biochem Biophys 202: 4353.
  • 7
    Vieth R, McCarten K, Norwich KH 1990 Role of 25-hydroxyvitamin D3 dose in determining rat 1,25-dihydroxyvitamin D3 production. Am J Physiol 258: E780E789.
  • 8
    Prosser DE, Jones G 2004 Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem Sci 29: 664673.
  • 9
    Suda T, Ueno Y, Fujii K, Shinki T 2003 Vitamin D and bone. J Cell Biochem 88: 259266.
  • 10
    Jesudason D, Need AG, Horowitz M, O'Loughlin PD, Morris HA, Nordin BE 2002 Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency. Bone 31: 626630.
  • 11
    Blank S, Scanlon KS, Sinks TH, Lett S, Falk H 1995 An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy. Am J Public Health 85: 656659.
  • 12
    Koutkia P, Chen TC, Holick MF 2001 Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 345: 6667.
  • 13
    Vieth R, Pinto T, Reen BS, Wong MM 2002 Vitamin D poisoning by table sugar. Lancet 359: 672.
  • 14
    Muskiet FA, Dijck-Brouwer DJ, van d V, Schaafsma A 2001 Do we really need >/=100 mcg vitamin D/d, and is it safe for all of us? Am J Clin Nutr 74: 862863.
  • 15
    DeLuca HF 2004 Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 80: 1689S1696S.
  • 16
    Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury SW 1972 The distribution and storage of vitamin D and its metabolites in human tissues. Clin Sci 43: 413431.
  • 17
    Narang NK, Gupta RC, Jain MK, Aaronson K 1984 Role of vitamin D in pulmonary tuberculosis. J Assoc Physicians India 32: 185186.
  • 18
    Vieth R 2006 Critique of the considerations for establishing the tolerable upper intake level for vitamin D: Critical need for revision upwards. J Nutr 136: 11171122.
  • 19
    Heaney RP 2003 Quantifying human calcium absorption using pharmacokinetic methods. J Nutr 133: 12241226.
  • 20
    Bouillon R, Verstuyf A, Verlinden L, Eelen G, Mathieu C 2003 Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases. Recent Results Cancer Res 164: 353356.
  • 21
    Posner GH 2002 Low-calcemic vitamin d analogs (deltanoids) for human cancer prevention. J Nutr 132: 3802S3803S.
  • 22
    van den Bemd GJ, Chang GT 2002 Vitamin D and vitamin D analogs in cancer treatment. Curr Drug Targets 3: 8594.
  • 23
    Vieth R 1990 The mechanisms of vitamin D toxicity. Bone Miner 11: 267272.
  • 24
    Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP 1995 Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Ann Intern Med 122: 511513.
  • 25
    Vieth R, Kessler MJ, Pritzker KP 1990 Species differences in the binding kinetics of 25-hydroxyvitamin D3 to vitamin D binding protein. Can J Physiol Pharmacol 68: 13681371.
  • 26
    Lou YR, Laaksi I, Syvala H, Blauer M, Tammela TL, Ylikomi T, Tuohimaa P 2004 25-Hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells. FASEB J 18: 332334.
  • 27
    Vieth R, Kimball S, Hu A, Walfish PG 2004 Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients. Nutr J 3: 8.
  • 28
    Barger-Lux MJ, Heaney RP, Dowell S, Chen TC, Holick MF 1998 Vitamin D and its major metabolites: Serum levels after graded oral dosing in healthy men. Osteoporos Int 8: 222230.
  • 29
    Vieth R 1999 Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr 69: 842856.
  • 30
    Barger-Lux MJ, Heaney RP 2002 Effects of above average summer sun exposure on serum 25-hydroxyvitamin d and calcium absorption. J Clin Endocrinol Metab 87: 49524956.
  • 31
    Brouwer DA, van Beek J, Ferwerda H, Brugman AM, van der Klis FR, van der Heiden HJ, Muskiet FA 1998 Rat adipose tissue rapidly accumulates and slowly releases an orally-administered high vitamin D dose. Br J Nutr 79: 527532.
  • 32
    Montgomery JL, Parrish FC Jr, Beitz DC, Horst RL, Huff-Lonergan EJ, Trenkle AH 2000 The use of vitamin D3 to improve beef tenderness. J Anim Sci 78: 26152621.
  • 33
    Vieth R 1994 Simple method for determining specific binding capacity of vitamin D-binding protein and its use to calculate the concentration of “free” 1,25-dihydroxyvitamin D. Clin Chem 40: 435441.
  • 34
    Briese S, Wiesner S, Will JC, Lembcke A, Opgen-Rhein B, Nissel R, Wernecke KD, Andreae J, Haffner D, Querfeld U 2006 Arterial and cardiac disease in young adults with childhood-onset end-stage renal disease-impact of calcium and vitamin D therapy. Nephrol Dial Transplant 21: 19061914.
  • 35
    Oh J, Wunsch R, Turzer M, Bahner M, Raggi P, Querfeld U, Mehls O, Schaefer F 2002 Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure. Circulation 106: 100105.
  • 36
    Tentori F, Hunt WC, Stidley CA, Rohrscheib MR, Bedrick EJ, Meyer KB, Johnson HK, Zager PG 2006 Mortality risk among hemodialysis patients receiving different vitamin D analogs. Kidney Int 70: 1858865.
  • 37
    Townsend K, Evans KN, Campbell MJ, Colston KW, Adams JS, Hewison M 2005 Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J Steroid Biochem Mol Biol 97: 103109.
  • 38
    Wolf M, Thadhani R 2007 Vitamin D in patients with renal failure: A summary of observational mortality studies and steps moving forward. J Steroid Biochem Mol Biol 103: 487490.
  • 39
    Hathcock J, Shao A, Vieth R, Heaney R 2007 A risk assessment for vitamin D. Am J Clin Nutr 85: 618.