SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B 1997 SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol 17: 172336172346.
  • 2
    Foster JW, Dominguez-Steglich MA, Guioli S, Kowk G, Weller PS, Stevanovic M, Weissenbach J, Mansour S, Young ID, Goodfellow PN, Brook JD, Schafer AJ 1994 Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 372: 525530.
  • 3
    Wagner T, Wirth J, Meyer J, Zabel BM, Held M, Zimmer J, Pasantes J, Bricarelli FD, Keutel J, Hustert E 1994 Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell 79: 11111120.
  • 4
    Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B 2002 The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 28132828.
  • 5
    Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B 1999 Sox9 is required for cartilage formation. Nat Genet 22: 8589.
  • 6
    Bi W, Huang W, Whitworth DJ, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B 2001 Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc Natl Acad Sci USA 98: 66986703.
  • 7
    Zelzer E, Olsen BR 2003 The genetic basis for skeletal diseases. Nature 423: 343348.
  • 8
    Akiyama H, Kim JE, Nakashima K, Balmes G, Iwai N, Deng JM, Zhang Z, Martin JF, Behringer RR, Nakamura T, de Crombrugghe B 2005 Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci USA 102: 1466514670.
  • 9
    Zhang P, Jimenez SA, Stokes DG 2003 Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9. J Biol Chem 278: 117123.
  • 10
    Bridgewater LC, Lefebvre V, de Crombrugghe B 1998 Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer. J Biol Chem 273: 1499815006.
  • 11
    Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, Shinomiya K, Nifuji A, Noda M 2000 SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. J Biol Chem 275: 1073810744.
  • 12
    Xie WF, Zhang X, Sakano S, Lefebvre V, Sandell LJ 1999 Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9. J Bone Miner Res 14: 757763.
  • 13
    Eames BF, Sharpe PT, Helms JA 2004 Hierarchy revealed in the specification of three skeletal fates by Sox9 and Runx2. Dev Biol 274: 188200.
  • 14
    Yamashiro T, Wang XP, Li Z, Oya S, Aberg T, Fukunaga T, Kamioka H, Speck NA, Takano-Yamamoto T, Thesleff I 2004 Possible roles of Runx1 and Sox9 in incipient intramembranous ossification. J Bone Miner Res 19: 16711677.
  • 15
    Uyama Y, Yagami K, Hatori M, Kakuta S, Nagumo M 2004 Recombinant human bone morphogenetic protein-2 promotes Indian hedgehog-mediated osteo-chondrogenic differentiation of a human chondrocytic cell line in vivo and in vitro. Differentiation 72: 3240.
  • 16
    Chikuda H, Kugimiya F, Hoshi K, Ikeda T, Ogasawara T, Shimoaka T, Kawano H, Kamekura H, Tsuchida A, Yokoi N, Nakamura K, Komeda K, Chung UI, Kawaguchi H 2004 Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev 18: 24182429.
  • 17
    Tsuda M, Takahashi S, Takahashi Y, Asahara H 2003 Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9. J Biol Chem 278: 2722427229.
  • 18
    Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B 2004 Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev 18: 10721087.
  • 19
    Huang W, Zhou X, Lefebvre V, de Crombrugghe B 2000 Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9′s ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol 20: 41494158.
  • 20
    Huang W, Chung UI, Kronenberg HM, de Crombrugghe B 2001 The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proc Natl Acad Sci USA 98: 160165.
  • 21
    Malki S, Nef S, Notarnicola C, Thevenet L, Gasca S, Mejean C, Berta P, Poulat F, Boizet-Bonhoure B 2005 Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation. EMBO J 24: 17981809.
  • 22
    Imamura T, Imamura C, Iwamoto Y, Sandell LJ 2005 Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein. J Biol Chem 280: 1662516634.
  • 23
    Mehlhorn AT, Niemeyer P, Kaschte K, Muller L, Finkenzeller G, Hartl D, Sudkamp NP, Schmal H 2007 Differential effects of BMP-2 and TGF-beta1 on chondrogenic differentiation of adipose derived stem cells. Cell Prolif 40: 809823.
  • 24
    zur Nieden NI, Kempka G, Rancourt DE, Ahr HJ 2005 Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages. BMC Dev Biol 5: 1.
  • 25
    Shea CM, Edgar CM, Einhorn TA, Gerstenfeld LC 2003 BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis. J Cell Biochem 90: 11121127.
  • 26
    Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T 1994 Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127: 17551766.
  • 27
    Shi Y, Massague J 2003 Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685700.
  • 28
    Massague J, Wotton D 2000 Transcriptional control by the TGF-beta/Smad signaling system. EMBO J 19: 17451754.
  • 29
    Zhao L, Yang S, Zhou GQ, Yang J, Ji D, Sabatakos G, Zhu T 2006 Downregulation of cAMP-dependent protein kinase inhibitor gamma is required for BMP-2-induced osteoblastic differentiation. Int J Biochem Cell Biol 38: 20642073.
  • 30
    Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H 2006 Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med 12: 14101416.
  • 31
    Huang WC, Xie Z, Konaka H, Sodek J, Zhau HE, Chung LW 2005 Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. Cancer Res 65: 23032313.
  • 32
    Matsuo N, Tanaka S, Gordon MK, Koch M, Yoshioka H, Ramirez F 2006 CREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblasts. J Biol Chem 281: 54455452.
  • 33
    Matsuyama M, Mizusaki H, Shimono A, Mukai T, Okumura K, Abe K, Shimada K, Morohashi K 2005 A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad. Genes Cells 10: 421434.
  • 34
    Tanaka K, Matsumoto Y, Nakatani F, Iwamoto Y, Yamada Y 2000 A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene. Mol Cell Biol 20: 44284435.
  • 35
    Kern B, Shen J, Starbuck M, Karsenty G 2001 Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes. J Biol Chem 276: 71017107.
  • 36
    Selvamurugan N, Pulumati MR, Tyson DR, Partridge NC 2000 Parathyroid hormone regulation of the rat collagenase-3 promoter by protein kinase A-dependent transactivation of core binding factor alpha1. J Biol Chem 275: 50375042.
  • 37
    Boguslawski G, Hale LV, Yu XP, Miles RR, Onyia JE, Santerre RF, Chandrasekhar S 2000 Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways. J Biol Chem 275: 9991006.
  • 38
    Zehentner BK, Dony C, Burtscher H 1999 The transcription factor Sox9 is involved in BMP-2 signaling. J Bone Miner Res 14: 17341741.
  • 39
    Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G 2006 ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab 4: 441451.
  • 40
    Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G 2004 ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117: 387398.
  • 41
    Piera-Velazquez S, Hawkins DF, Whitecavage MK, Colter DC, Stokes DG, Jimenez SA 2007 Regulation of the human SOX9 promoter by Sp1 and CREB. Exp Cell Res 313: 10691079.
  • 42
    Furumatsu T, Tsuda M, Yoshida K, Taniguchi N, Ito T, Hashimoto M, Ito T, Asahara H 2005 Sox9 and p300 cooperatively regulate chromatin-mediated transcription. J Biol Chem 280: 3520335208.
  • 43
    Kawakami Y, Tsuda M, Takahashi S, Taniguchi N, Esteban CR, Zemmyo M, Furumatsu T, Lotz M, Belmonte JC, Asahara H 2005 Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. Proc Natl Acad Sci USA 102: 24142419.
  • 44
    Wang BL, Dai CL, Quan JX, Zhu ZF, Zheng F, Zhang HX, Guo SY, Guo G, Zhang JY, Qiu MC 2006 Parathyroid hormone regulates osterix and Runx2 mRNA expression predominantly through protein kinase A signaling in osteoblast-like cells. J Endocrinol Invest 29: 101108.