Original Article

You have full text access to this OnlineOpen article

Radiographic texture analysis of densitometric calcaneal images: Relationship to clinical characteristics and to bone fragility

  1. Tamara Vokes1,*,
  2. Diane Lauderdale2,
  3. Siu-Ling Ma1,
  4. Mike Chinander3,
  5. Keona Childs1,
  6. Maryellen Giger3

Article first published online: 14 DEC 2009

DOI: 10.1359/jbmr.090714

Issue

Journal of Bone and Mineral Research

Journal of Bone and Mineral Research

Volume 25, Issue 1, pages 56–63, January 2010

Additional Information

How to Cite

Vokes, T., Lauderdale, D., Ma, S.-L., Chinander, M., Childs, K. and Giger, M. (2010), Radiographic texture analysis of densitometric calcaneal images: Relationship to clinical characteristics and to bone fragility. J Bone Miner Res, 25: 56–63. doi: 10.1359/jbmr.090714

Author Information

  1. 1

    Departments of Medicine, The University of Chicago, Chicago, IL, USA

  2. 2

    Health Studies, The University of Chicago, Chicago, IL, USA

  3. 3

    Radiology, The University of Chicago, Chicago, IL, USA

*Department of Medicine, Section of Endocrinology, University of Chicago, 5841 S. Maryland, MC1027, Chicago, IL 60637, USA.

Publication History

  1. Issue published online: 20 JAN 2010
  2. Article first published online: 14 DEC 2009
  3. Manuscript Accepted: 6 JUL 2009
  4. Manuscript Revised: 22 MAY 2009
  5. Manuscript Received: 23 MAR 2009

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (108K)

References

  • 1
    Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996; 312: 1254–1259.
  • 2
    Ross PD, Davis JW, Vogel JM, Wasnich RD. A critical review of bone mass and the risk of fractures in osteoporosis. Calcif Tissue Int. 1990; 46: 149–161.
  • 3
    Siris ES, Brenneman SK, Barrett-Connor E, et al. The effect of age and bone mineral density on the absolute, excess, and relative risk of fracture in postmenopausal women aged 50–99: results from the National Osteoporosis Risk Assessment (NORA). Osteoporos Int. 2006; 17: 565–574.
  • 4
    Wainwright SA, Marshall LM, Ensrud KE, et al. Hip fracture in women without osteoporosis. J Clin Endocrinol Metab. 2005; 90: 2787–2793.
  • 5
    Carballido-Gamio J, Majumdar S. Clinical utility of microarchitecture measurements of trabecular bone. Curr Osteoporos Rep. 2006; 4: 64–70.
  • 6
    Caligiuri P, Giger ML, Favus M. Multifractal radiographic analysis of osteoporosis. Med Phys. 1994; 21: 503–508.
  • 7
    Caligiuri P, Giger ML, Favus MJ, Jia H, Doi K, Dixon LB. Computerized radiographic analysis of osteoporosis: preliminary evaluation. Radiology 1993; 186: 471–474.
  • 8
    Gregory JS, Stewart A, Undrill PE, Reid DM, Aspden RM. Identification of hip fracture patients from radiographs using Fourier analysis of the trabecular structure: a cross-sectional study. BMC Med Imaging 2004; 4: 4.
  • 9
    Pothuaud L, Lespessailles E, Harba R, et al. Fractal analysis of trabecular bone texture on radiographs: discriminant value in postmenopausal osteoporosis. Osteoporos Int 1998; 8: 618–625.
  • 10
    Benhamou CL, Poupon S, Lespessailles E, et al. Fractal analysis of radiographic trabecular bone texture and bone mineral density: two complementary parameters related to osteoporotic fractures. J Bone Miner Res 2001; 16: 697–704.
    Direct Link:
  • 11
    Lespessailles E, Roux JP, Benhamou CL, et al. Fractal analysis of bone texture on os calcis radiographs compared with trabecular microarchitecture analyzed by histomorphometry. Calcif Tissue Int 1998; 63: 121–125.
  • 12
    Lespessailles E, Jullien A, Eynard E, et al. Biomechanical properties of human os calcanei: relationships with bone density and fractal evaluation of bone microarchitecture. J Biomech 1998; 31: 817–824.
  • 13
    Chinander MR, Giger ML, Martell JM, Jiang C, Favus MJ. Computerized radiographic texture measures for characterizing bone strength: a simulated clinical setup using femoral neck specimens. Med Phys. 1999; 26: 2295–2300.
  • 14
    Prouteau S, Ducher G, Nanyan P, Lemineur G, Benhamou L, Courteix D. Fractal analysis of bone texture: a screening tool for stress fracture risk? Eur J Clin Invest. 2004; 34: 137–142.
    Direct Link:
  • 15
    Wilkie JR, Giger ML, Chinander MR, Vokes TJ, Nishikawa RM, Carlin MD. Investigation of physical image quality indices of a bone densitometry system. Med Phys. 2004; 31: 873–881.
  • 16
    Vokes TJ, Pham A, Wilkie J, et al. Reproducibility and sources of variability in radiographic texture analysis of densitometric calcaneal images. J Clin Densitom. 2008; 11: 211–220.
  • 17
    Wilkie JR, Giger ML, Chinander MR, et al. Comparison of radiographic texture analysis from computed radiography and bone densitometry systems. Med Phys. 2004; 31: 882–891.
  • 18
    Vokes TJ, Giger ML, Chinander MR, Karrison TG, Favus MJ, Dixon LB. Radiographic texture analysis of densitometer-generated calcaneus images differentiates postmenopausal women with and without fractures. Osteoporos Int. 2006; 17: 1472–1482.
  • 19
    Genant HK, Wu CY, van Kuijk C, Nevitt MC. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 1993; 8: 1137–1148.
    Direct Link:
  • 20
    Vokes T, Bachman D, Baim S, et al. Vertebral fracture assessment: the 2005 ISCD official positions. J Clin Densitom. 2006; 9: 37–46.
  • 21
    Schousboe JT, Vokes T, Broy SB, et al. Vertebral fracture assessment: the 2007 ISCD official positions. J Clin Densitom. 2008; 11: 92–108.
  • 22
    Lin JC, Amling M, Newitt DC, et al. Heterogeneity of trabecular bone structure in the calcaneus using magnetic resonance imaging. Osteoporos Int. 1998; 8: 16–24.
  • 23
    Wehrli FW, Hilaire L, Fernandez-Seara M. Gomberg. et al. Quantitative magnetic resonance imaging in the calcaneus and femur of women with varying degrees of osteopenia and vertebral deformity status. J Bone Miner Res. 2002; 17: 2265–2273.
    Direct Link:
  • 24
    Li H, Giger ML, Olopade OI, Chinander MR. Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment. J Digit Imaging 2008; 21: 145–152.
  • 25
    Lespessailles E, Gadois C, Kousignian I, et al. Clinical interest of bone texture analysis in osteoporosis: a case control multicenter study. Osteoporos Int. 2008; 19: 1019–1028.
  • 26
    Chappard D, Pascaretti-Grizon F, Gallois Y, Mercier P, Basle MF, Audran M. Medullar fat influences texture analysis of trabecular microarchitecture on X-ray radiographs. Eur J Radiol. 2006; 58: 404–410.
  • 27
    Vallarta-Ast N, Krueger D, Wrase C, Agrawal S, Binkley N. An evaluation of densitometric vertebral fracture assessment in men. Osteoporos Int 2007; 18: 1405–1410.
  • 28
    Lindsay R, Silverman SL, Cooper C, et al. Risk of new vertebral fracture in the year following a fracture. JAMA. 2001; 285: 320–323.
  • 29
    Delmas PD, Genant HK, Crans GG, et al. Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Bone 2003; 33: 522–532.
  • 30
    McCloskey EV, Vasireddy S, Threlkeld J, et al. Vertebral fracture assessment (VFA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis. J Bone Miner Res. 2008; 23: 1561–1568.
    Direct Link:
  • 31
    Black DM, Bouxsein ML, Marshall LM, et al. Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT. J Bone Miner Res. 2008; 23: 1326–1333.
    Direct Link:
  • 32
    Lespessailles E, Gadois C, Lemineur G, Do-Huu JP, Benhamou L. Bone texture analysis on direct digital radiographic images: precision study and relationship with bone mineral density at the os calcis. Calcif Tissue Int. 2007; 80: 97–102.
View Full Article (HTML) Get PDF (108K)