Original Article

You have full text access to this OnlineOpen article

Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis

  1. Christian Roux1,*,
  2. Jacques Fechtenbaum1,
  3. Sami Kolta1,
  4. Roula Said-Nahal1,
  5. Karine Briot1,
  6. Claude-Laurent Benhamou2

Article first published online: 14 DEC 2009

DOI: 10.1359/jbmr.090727

Issue

Journal of Bone and Mineral Research

Journal of Bone and Mineral Research

Volume 25, Issue 2, pages 362–368, February 2010

Additional Information

How to Cite

Roux, C., Fechtenbaum, J., Kolta, S., Said-Nahal, R., Briot, K. and Benhamou, C.-L. (2010), Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis. J Bone Miner Res, 25: 362–368. doi: 10.1359/jbmr.090727

Author Information

  1. 1

    Paris-Descartes University, Cochin Hospital, Rheumatology Department, Paris, France

  2. 2

    INSERM U 658, Orleans, France

*Cochin Hospital, 27, rue du Faubourg St, Jacques, Paris 75014, France.

Publication History

  1. Issue published online: 19 FEB 2010
  2. Article first published online: 14 DEC 2009
  3. Manuscript Accepted: 8 JUL 2009
  4. Manuscript Revised: 24 NOV 2008
  5. Manuscript Received: 24 SEP 2008

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (125K)

References

  • 1
    Kado DM, Huang MH, Barrett-Connor E, Greendale GA. Kyphotic posture and poor physical functional ability in older community dwelling men and women: the Rancho Bernardo Study. J Gerontol Med Sci. 2005; 60: 633–637.
  • 2
    Ensrud KE, Black DM, Harris F, Ettinger B, Cummings SR. Correlates of kyphosis in older women: the Fracture Intervention Trial Research Group. J Am Geriatr Soc. 1997; 45: 682–687.
  • 3
    Sinaki M, Brey RH, Hughes CA, Larson DR, Kaufman KR. Balance disorder and increased risk of falls in osteoporosis and kyphosis: significance of kyphotic posture and muscle strength. Osteoporos Int. 2005; 16: 1004–1010.
  • 4
    Harrison RA, Kiminoski K, Vethanayagam D, Majumdar SR. Osteoporosis-related kyphosis and impairments in pulmonary function: a systematic review. J Bone Miner Res. 2007; 22: 447–457.
  • 5
    Yamaguchi T, Sugimoto T, Yamada H, et al. The presence and severity of vertebral fractures is associated with the presence of esophageal hiatal hernia in postmenopausal women. Osteoporos Int. 2002; 13: 331–336.
  • 6
    Kado DM, Huang MH, Karlamangla A, Barrett-Connor E, Greendale GA. Hyperkyphotic posture predicts mortality in older community dwelling men and women: a prospective study. J Am Geriatr Soc. 2004; 62: 1662–1667.
  • 7
    Kado DM, Greendale GA, Lui L, et al. Hyperkyphosis predicts mortality independent of vertebral osteoporosis in older women. J Bone Miner Res. 2003; 18: S249.
  • 8
    Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR. Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group. Arch Intern Med. 1999; 159: 1215–1220.
  • 9
    Milne JS, Williamson J. A longitudinal study of kyphosis in older people. Age Ageing. 1983; 12: 225–233.
  • 10
    Bartynski WS, Heller MT, Grahovac SZ, Rothfus WE, Kurs-Lasky M. Severe thoracic kyphosis in the older patient in the absence of vertebral fracture: association of extreme curve with age. Am J Neuroradiol. 2005; 26: 2077–2085.
  • 11
    Roux C, Fechtenbaum J, Kolta S, Briot K, Girard M. Mild prevalent and incident vertebral fractures are risk factors for new fractures. Osteoporos Int. 2007; 18: 1617–1624.
  • 12
    Schneider DL, von Mühlen DG, Barrett-Connor E, Sartoris D. Kyphosis does not equal vertebral fractures: the Rancho Bernard Study. J Rheumatol. 2004; 31: 747–752.
  • 13
    Manns RA, Haddaway MJ, McCall IW, Cassar PV, Davie MW. The relative contribution of disc and vertebral morphometry to the angle of kyphosis in asymptomatic subjects. Clin Radiol. 1996; 51: 258–262.
  • 14
    Huang MH, Barrett-Connor E, Greendale GA, Kado DM. Hyperkyphotic posture and risk of future osteoporotic fractures: the Rancho Bernardo Study. J Bone Miner Res. 2006; 21: 419–423.
  • 15
    Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med. 2004; 350: 459–468.
  • 16
    Reginster JY, Seeman E, de Vernejoul MC, et al. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab. 2005; 90: 2816–2822.
  • 17
    Genant HK, Wu CY, Van Kuijk C, Nevitt MC. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 1991; 6: 25–34.
  • 18
    Smith-Bindman R, Cummings SR, Steiger P, Genant HK. A comparison of morphometric definitions of vertebral fracture. J Bone Miner Res. 1991; 6: 25–34.
  • 19
    Ware JE, Snow KK, Kosinski MK, et al., SF-36 Health Survey, Manual and Interpretation Guide. Boston: The Health Institute, New England Medical Center.
  • 20
    Ettinger B, Black DM, Palermo L, Nevitt MC, Melnikoff S, Cummings SR. Kyphosis in older women and its relation to back pain, disability and osteopenia: the Study of Osteoporotic Fractures. Osteoporos Int. 1994; 4: 55–60.
  • 21
    Prince RL, Devine A, Dick IM. The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformities. Osteoporos Int. 2007; 18: 621–627.
  • 22
    Ferrar L, Jiang G, Adams J, Eastell R. Identification of vertebral fractures: an update. Osteoporos Int. 2005; 16: 717–728.
  • 23
    Jiang G, Barrington NA, Eastell R, Ferrar L. Visual identification of prevalent vertebral fracture: comparison between methods. Osteoporos Int. 2004; 15: 887–896.
  • 24
    Abdul-Hamid Osman A, Bassionni H, Koutri R, Nus J, Geusens P, Dequeker J. Aging of the thoracic spine: distinction between wedging in osteoarthritis and fracture in osteoporosis—a cross-sectional and longitudinal study. Bone. 1994; 15: 437–442.
  • 25
    Marquis P, Roux C, de la Loge C, et al. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. Osteoporos Int. 2008; 19: 503–510.
  • 26
    Bruyere O, Delferriere D, Roux C, et al. Effects of strontium ranelate on spinal osteoarthritis progression. Ann Rheum Dis. 2008; 67: 335–339.
  • 27
    Neogi T, Nevitt MC, Ensrud KE, Bauer D, Felson DT. The effect of alendronate on progression of spinal osteophytes and disk space narrowing. Ann Rheum Dis. 2008; 67: 1427–1430.
  • 28
    Mika A, Unnithan VB, Mika P. Differences in thoracic kyphosis and in back muscle strength in women with bone loss due to osteoporosis. Spine. 2005; 30: 241–246.
  • 29
    Martin AR, Sornay-Rendu E, Chandler JM, Duboeuf F, Girman CJ, Delmas PD. The impact of osteoporosis on quality of life: the OFELY cohort. Bone. 2002; 31: 32–36.
View Full Article (HTML) Get PDF (125K)