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Trabecular volumetric bone mineral density is associated with previous fracture during childhood and adolescence in males: The GOOD study

  1. Anna Darelid,
  2. Claes Ohlsson,
  3. Robert Rudäng,
  4. Jenny M Kindblom,
  5. Dan Mellström,
  6. Mattias Lorentzon*

Article first published online: 18 MAR 2010

DOI: 10.1359/jbmr.090824

Issue

Journal of Bone and Mineral Research

Journal of Bone and Mineral Research

Volume 25, Issue 3, pages 537–544, March 2010

Additional Information

How to Cite

Darelid, A., Ohlsson, C., Rudäng, R., Kindblom, J. M., Mellström, D. and Lorentzon, M. (2010), Trabecular volumetric bone mineral density is associated with previous fracture during childhood and adolescence in males: The GOOD study. J Bone Miner Res, 25: 537–544. doi: 10.1359/jbmr.090824

Author Information

  1. Center for Bone Research at the Sahlgrenska Academy (CBS), Department of Medicine, Gothenburg University, Gothenburg, Sweden

*Division of Endocrinology, Department of Medicine, Gröna Stråket 8, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden.

Publication History

  1. Issue published online: 18 MAR 2010
  2. Article first published online: 18 MAR 2010
  3. Accepted manuscript online: 27 JAN 2010 12:00AM EST
  4. Manuscript Accepted: 27 AUG 2009
  5. Manuscript Revised: 30 JUN 2009
  6. Manuscript Received: 5 MAY 2009

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References

  • 1
    Strom O, Borgstrom F, Zethraeus N, et al. Long-term cost and effect on quality of life of osteoporosis-related fractures in Sweden. Acta Orthop. 2008; 79: 269–280.
  • 2
    Cummings SR, Black DM, Nevitt MC, et al. Bone density at various sites for prediction of hip fractures: the Study of Osteoporotic Fractures Research Group. Lancet. 1993; 341: 72–75.
  • 3
    Johnell O, Kanis JA, Oden A, et al. Predictive value of BMD for hip and other fractures. J Bone Miner Res. 2005; 20: 1185–1194.
    Direct Link:
  • 4
    Clark EM, Tobias JH, Ness AR. Association between bone density and fractures in children: a systematic review and meta-analysis. Pediatrics. 2006; 117: e291–297.
  • 5
    Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP. Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004; 19: 1976–1981.
    Direct Link:
  • 6
    Landin LA. Epidemiology of children's fractures. J Pediatr Orthop B. 1997; 6: 79–83.
  • 7
    Hagino H, Yamamoto K, Teshima R, Kishimoto H, Nakamura T. Fracture incidence and bone mineral density of the distal radius in Japanese children. Arch Orthop Trauma Surg. 1990; 109: 262–264.
  • 8
    Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ. Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy X-ray absorptiometry study. J Pediatr. 2001; 139: 509–515.
  • 9
    Landin LA. Fracture patterns in children: analysis of 8682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950–1979. Acta Orthop Scand Suppl. 1983; 202: 1–109.
  • 10
    Kramhoft M, Bodtker S. Epidemiology of distal forearm fractures in Danish children. Acta Orthop Scand. 1988; 59: 557–579.
  • 11
    Yeh FJ, Grant AM, Williams SM, Goulding A. Children who experience their first fracture at a young age have high rates of fracture. Osteoporos Int. 2006; 17: 267–272.
  • 12
    Jones IE, Williams SM, Dow N, Goulding A. How many children remain fracture-free during growth? A longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study. Osteoporos Int. 2002; 13: 990–995.
  • 13
    Khosla S, Melton LJ III, Dekutoski MB, Achenbach SJ, Oberg AL, Riggs BL. Incidence of childhood distal forearm fractures over 30 years: a population-based study. JAMA. 2003; 290: 1479–1485.
  • 14
    Davies JH, Evans BA, Gregory JW. Bone mass acquisition in healthy children. Arch Dis Child. 2005; 90: 373–378.
  • 15
    Ferrari SL, Chevalley T, Bonjour JP, Rizzoli R. Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility? J Bone Miner Res. 2006; 21: 501–507.
    Direct Link:
  • 16
    Bianchi ML. Osteoporosis in children and adolescents. Bone. 2007; 41: 486–495.
  • 17
    Clark EM, Ness AR, Bishop NJ, Tobias JH. Association between bone mass and fractures in children: a prospective cohort study. J Bone Miner Res. 2006; 21: 1489–1495.
    Direct Link:
  • 18
    Goulding A, Cannan R, Williams SM, Gold EJ, Taylor RW, Lewis-Barned NJ. Bone mineral density in girls with forearm fractures. J Bone Miner Res. 1998; 13: 143–148.
    Direct Link:
  • 19
    Flynn J, Foley S, Jones G. Can BMD assessed by DXA at age 8 predict fracture risk in boys and girls during puberty? An eight-year prospective study. J Bone Miner Res. 2007; 22: 1463–1467.
    Direct Link:
  • 20
    Nevitt MC, Cummings SR, Browner WS, et al. The accuracy of self-report of fractures in elderly women: evidence from a prospective study. Am J Epidemiol. 1992; 135: 490–499.
  • 21
    Skaggs DL, Loro ML, Pitukcheewanont P, Tolo V, Gilsanz V. Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures. J Bone Miner Res. 2001; 16: 1337–1342.
    Direct Link:
  • 22
    Lorentzon M, Mellstrom D, Ohlsson C. Association of amount of physical activity with cortical bone size and trabecular volumetric BMD in young adult men: the GOOD Study. J Bone Miner Res. 2005; 20: 1936–1943.
    Direct Link:
  • 23
    Kindblom JM, Lorentzon M, Norjavaara E, et al. Pubertal timing predicts previous fractures and BMD in young adult men: the GOOD Study. J Bone Miner Res. 2006; 21: 790–795.
    Direct Link:
  • 24
    Karlberg J. On the modelling of human growth. Stat Med. 1987; 6: 185–192.
    Direct Link:
  • 25
    Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996; 312: 1254–1259.
  • 26
    Melton LJ 3rd, Riggs BL, van Lenthe GH, et al. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. 2007; 22: 1442–1448.
    Direct Link:
  • 27
    Melton LJ 3rd, Riggs BL, Keaveny TM, et al. Structural determinants of vertebral fracture risk. J Bone Miner Res. 2007; 22: 1885–1892.
    Direct Link:
  • 28
    Kirmani S, Christen D, van Lenthe GH, et al. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. 2009; 24: 1033–1042.
    Direct Link:
  • 29
    Faulkner RA, Davison KS, Bailey DA, Mirwald RL, Baxter-Jones AD. Size-corrected BMD decreases during peak linear growth: implications for fracture incidence during adolescence. J Bone Miner Res. 2006; 21: 1864–1870.
    Direct Link:
  • 30
    Mackey DC, Lui LY, Cawthon PM, et al. High-trauma fractures and low bone mineral density in older women and men. JAMA. 2007; 298: 2381–2388.
  • 31
    Clark EM, Ness AR, Tobias JH. Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma. J Bone Miner Res. 2008; 23: 173–179.
    Direct Link:
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