Part of this study has been presented in abstract form at the Dutch Society of Bone and Calcium Metabolism, Papendal, November 1995, and World Congress on Osteoporosis, Amsterdam, The Netherlands, May 1996.
Reduced Bone Mass in Dutch Adolescents Fed a Macrobiotic Diet in Early Life†
Article first published online: 1 SEP 1997
Copyright © 1997 ASBMR
Journal of Bone and Mineral Research
Volume 12, Issue 9, pages 1486–1494, September 1997
How to Cite
Parsons, T. J., van Dusseldorp, M., van Der Vliet, M., van de Werken, K., Schaafsma, G. and van Staveren, W. A. (1997), Reduced Bone Mass in Dutch Adolescents Fed a Macrobiotic Diet in Early Life. J Bone Miner Res, 12: 1486–1494. doi: 10.1359/jbmr.1922.214.171.1246
- Issue published online: 4 DEC 2009
- Article first published online: 1 SEP 1997
- Manuscript Accepted: 5 MAY 1997
- Manuscript Revised: 7 APR 1997
- Manuscript Received: 18 NOV 1996
This study investigated the effect of a macrobiotic (vegan-type) diet, low in calcium and vitamin D, consumed in early life, on bone mineral during adolescence. Bone mineral content (BMC) and bone area were measured in 195 adolescents (103 girls, 92 boys) aged 9–15 years, using dual-energy X-ray absorptiometry. Ninety-three adolescents (43 girls, 50 boys) had followed a macrobiotic diet in childhood, and 102 (60 girls, 42 boys) were control subjects. After adjustment for bone area, weight, height, percent body lean, age, and puberty, BMC was significantly lower in macrobiotic subjects, in boys and girls, respectively, at the whole body, −3.4% and −2.5%, spine, −8.5% and −5.0%, femoral neck, −8.0% and −8.2%, midshaft radius, −6.8% and −5.6%, and also in girls, at the trochanter, −5.8% (p < 0.05). No group differences were observed at the wrist. Group differences were not explained by current calcium intake or physical activity. We conclude that the use of a macrobiotic diet in early childhood negatively influences adjusted bone mass at age 9–15 years, observations which may hold important implications for fracture risk in later life.