• 1
    Hui SL, Slemenda CW, Johnston CCJ 1988 Age and bone mass as predictors of fracture in a prospective study J Clin Invest 81:18041809.
  • 2
    Cummings SR, Black DM, Nevitt MC et al. 1990 Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group JAMA 263:665668.
  • 3
    Nguyen T, Sambrook P, Kelly P, Jones G, Lord S, Freund J, Eisman J 1993 Prediction of osteoporotic fractures by postural instability and bone density BMJ 307:11111115.
  • 4
    Tokita A, Watanabe T, Miura Y, Yabuta K, Mathumoto H, Yamamori S, Morrison N, Eisman JA 1995 Vitamin D receptor RFLP and bone mineral density in Japanese Bone 16 (Suppl 1):83S.
  • 5
    Gunzer C, Morrison NA, Eisman JA 1995 Genetic effect of the vitamin D receptor gene on bone density by pQCT in continental Europeans Bone 16 (Suppl 1):84S.
  • 6
    Houston LA, Grant SFA, Reid DM, Ralston SH 1996 Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: Studies in a U.K. population Bone 18:249252.
  • 7
    Spector TD, Keen RW, Arden NK et al. 1995 Influence of vitamin D receptor genotype on bone mineral density in postmenopausal women: A twin study in Britain BMJ 310:13571360.
  • 8
    Hustmyer FG, Peacock M, Hui S, Johnston CC, Christian J 1994 Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus J Clin Invest 94:21302134.
  • 9
    Gallagher JC, Goldgar D, Kinyamu H, Fannon P 1994 Vitamin D receptor genotypes in type I osteoporosis J Bone Miner Res 9:S143.
  • 10
    Shiraki M, Eguchi H, Aoki C, Shiraki Y 1995 Can allelic variations in vitamin D receptor gene predict bone densities and serum osteocalcin levels in Japanese women? Bone 16 (Suppl 1):84S.
  • 11
    Looney JE, Yoon HK, Fischer M, Farley SM, Farley JR, Wergedal JE, Baylink DJ 1995 Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women J Clin Endocrinol Metab 80:21582162.
  • 12
    Lander ES, Botstein D 1989 Mapping mendelian factors underlying quantitative traits using RFLP linkage maps Genetics 121:185199.
  • 13
    Lander ES, Schork NJ 1994 Genetic dissection of complex traits Science 265:20372048.
  • 14
    Dietrich W, Katz H, Lincoln SE, Shin HS, Friedman J, Dracopoli NC, Lander ES 1992 A genetic map of the mouse suitable for typing intraspecific crosses Genetics 131:423447.
  • 15
    Dietrich WF, Miller JC, Steen RG, Merchant M, Damron D, Nahf R, Gross A, Joyce DC, Wessel M, Dredge RD 1994 A genetic map of the mouse with 4,006 simple sequence length polymorphisms Nat Genet 7:220245.
  • 16
    Paterson AH, Lander ES, Hewitt JD, Peterson S, Lincoln SE, Tanksley SD 1988 Resolution of quantitative traits into Mendelian factors using a complete linkage map of restriction fragment polymorphisms Nature 335:721726.
  • 17
    Jacob HJ, Lindpaintner K, Lincoln SE, Kusumi K, Bunker RK, Mao YP, Ganten D, Dzau VJ, Lander ES 1991 Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat Cell 67:213224.
  • 18
    Hilbert P, Lindpaintner K, Beckman JS, Serikawa T, Soubrier F, Dubay C, Cartwright P, DeGouyon B, Julier C, Takahashi S 1991 Chromosomal mapping of two genetic loci associated with blood pressure regulation in hereditary hypertensive rats Nature 353:521529.
  • 19
    Rise ML, Frankel WN, Coffin JM, Seyfried TN 1991 Genes for epilepsy mapped in the mouse Science 253:669673.
  • 20
    Plomin R, McClearn GE, Gora Maslak G, Neiderhiser JM 1991 Use of recombinant inbred strains to detect quantitative trait loci associated with behavior Behav Genet 21:99116.
  • 21
    Dietrich WF, Copeland NG, Gilbert DJ, Miller JC, Jenkins NA, Lander ES 1995 Mapping of the mouse genome: Current status and future prospects Proc Natl Acad Sci USA 92:1084910853.
  • 22
    Copeland NG, Jenkins NA, Gilbert DJ, Eppig JT, Maltais LJ, Miller JC, Dietrich WF, Weaver A, Lincoln SE, Steen RG, Stein LD, Nadeau JH, Lander ES 1993 A genetic linkage map of the mouse: Current applications and future prospects Science 262:5766.
  • 23
    Silver LM, Nadeau JH 1997 Encyclopedia of the mouse genome Mamm Genome 7:S1S388.
  • 24
    Taylor BA 1978 Recombinant inbred strains: Use in gene mapping. In: MorseHC (ed.) Origins of Inbred Mice. Academic Press, New York, NY, U.S.A., pp. 423438.
  • 25
    Bailey DW 1981 Recombinant inbred strains and bilineal congenic strains. In: FosterHL, SmallJD, FoxJG (eds.) The Mouse in Biomedical Research. Academic Press, New York, NY, U.S.A., pp. 223239.
  • 26
    Silver LM 1995 Mouse Genetics: Concepts and Applications, Oxford University Press, New York, NY, U.S.A., pp. 209.
  • 27
    Gora-Maslak G, McClearn GE, Crabbe JC, Phillips TJ, Belknap JK, Plomin R 1991 Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology Psychopharmacol (Berl) 104:413424.
  • 28
    Plomin R, McClearn GE 1993 Quantitative trait loci (QTL) analyses and alcohol-related behaviors Behav Genet 23:197211.
  • 29
    Allison DB, Kaprio J, Korkeila M, Koskenvuo M, Neale MC, Hayakawa K 1996 The heritability of body mass index among an international sample of monozygotic twins reared apart Int J Obes Relat Metab Disord 20:501506.
  • 30
    Herskind AM, McGue M, Sorensen TI, Harvald B 1996 Sex and age specific assessment of genetic and environmental influences on body mass index in twins Int J Obes Relat Metab Disord 20:106113.
  • 31
    Forbes GB, Sauer EP, Weitkamp LR 1995 Lean body mass in twins Metabolism 44:14421446.
  • 32
    Moll PP, Burns TL, Lauer RM 1991 The genetic and environmental sources of body mass index variability: The Muscatine Ponderosity Family Study Am J Hum Genet 49:12431255.
  • 33
    Teegarden D, Proulx WR, Martin BR, Zhao J, McCabe GP, Lyle RM, Peacock M, Slemenda C, Johnston CC, Weaver CM 1995 Peak bone mass in young women J Bone Miner Res 10:711715.
  • 34
    Young D, Hopper JL, Nowson CA, Green RM, Sherwin AJ, Kaymakci B, Smid M, Guest CS, Larkins RG, Wark JD 1995 Determinants of bone mass in 10- to 26-year-old females: A twin study J Bone Miner Res 10:558567.
  • 35
    Casez J-P, Muehlbauer RC, Lippuner K, Kelly T, Fleisch H, Jaeger P 1994 Dual-energy x-ray absorptiometry for measuring total bone mineral content in the rat: Study of accuracy and precision Bone Miner 26:6168.
  • 36
    Safadi M, Shapira D, Leichter I, Reznick A, Silbermann M 1988 Ability of different techniques of measuring bone mass to determine vertebral bone loss in aging female rats Calcif Tissue Int 42:375382.
  • 37
    Kimmel DB, Wronski TJ 1990 Nondestructive measurement of bone mineral in femurs from ovariectomized rats Calcif Tissue Int 46:101110.
  • 38
    Manly KE, Cudmore R 1995 Map Manager: A Program for Genetic Mapping, Ed, 2.6.5. Buffalo, NY: Roswell Park Cancer Institute, Buffalo, NY, U.S.A.
  • 39
    Belknap JK, Crabbe JC, Plomin R, McClearn GE, Sampson KE, O'Toole LA, Gora-Maslak G 1992 Single-locus control of saccharin intake in BXD/Ty recombinant inbred (RI) mice: Some methodological implications for RI strain analysis Behav Genet 22:81100.
  • 40
    Wilkinson L 1990 Systat: The system for statistics, Ed, 5.0/6.0. Systat, Inc., Evanston, IL, U.S.A.
  • 41
    Belknap JK, Mitchell SR, O'Toole LA, Helms ML, Crabbe JC 1996 Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains Behav Genet 26:149160.
  • 42
    Lander ES, Kruglyak L 1995 Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results Nat Genet 11:241247.
  • 43
    Kaye M, Kusy RP 1995 Genetic lineage, bone mass, and physical activity Bone 17:131135.
  • 44
    Jilka RL, Weinstein RS, Takahashi K, Parfitt AM, Manolagas SC 1996 Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence J Clin Invest 97:17321740.
  • 45
    Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC 1997 The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage Endocrinology 138:40134021.
  • 46
    Kelly PJ, Eisman JA, Sambrook PN 1990 Interaction of genetic and environmental influences on peak bone density Osteoporos Int 1:5660.
  • 47
    Krall EA, Dawson-Hughes B 1993 Heritable and life-style determinants of bone mineral density J Bone Miner Res 8:19.
  • 48
    Belknap JJ, Dubay C, Crabbe JC, Buck KJ 1997 Mapping quantitative trait loci for behavioral traits in the mouse. In: BlumK, NobleEP (eds.) Handbook of Psychiatric Genetics. CRC Press, New York, NY, U.S.A., pp. 435453.
  • 49
    Matsushita M, Tsuboyama T, Kasai R, Okumura H, Yamamuro T, Higuchi A, Kohno A, Yonezu T, Utani A 1986 Age-related changes in bone mass in the senescence-accelerated mouse (SAM): SAM-R/3 and SAM-P/6 as new murine models for senile osteoporosis Am J Pathol 125:276283.
  • 50
    Beamer WG, Donahue LR, Rosen CJ, Baylink DJ 1996 Genetic variability in adult bone density among inbred strains of mice Bone 18:397403.
  • 51
    Rosen CJ, Dimai HP, Vereault D, Donahue LR, Beamer WG, Farley J, Linkhart S, Linkhart T, Mohan S, Baylink DJ 1997 Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities Bone 21:217223.
  • 52
    Crabbe JC, Belknap JK, Buck KJ 1994 Genetic animal models of alcohol and drug abuse Science 264:17151723.
  • 53
    Johnson ML, Gong G, Kimberling W, Recker SM, Kimmel DB, Recker RB 1997 Linkage of a gene causing high bone mass to human chromosome 11 (11q12–13) Am J Hum Genet 60:13261332.
  • 54
    Mahaney MC, Morin P, Rodriguez LA, Newman DE, Rogers J 1997 A quantitative trait locus on chromosome 11 may influence bone mineral density at several sites: Linkage analyses in pedigreed baboons J Bone Miner Res 12 (Suppl 1):S118 (abstrat 64).
  • 55
    Liel Y, Edwards J, Shary J, Spicer KM, Gordon L, Bell NH 1988 The effects of race and body habitus on bone mineral density of the radius, hip, and spine in premenopausal women J Clin Endocrinol Metab 66:12471250.
  • 56
    Slemenda CW, Hui SL, Longcope C, Wellman H, Johnston CC Jr 1990 Predictors of bone mass in perimenopausal women: A prospective study of clinical data using photon absorptiometry Ann Intern Med 112:96101.
  • 57
    Bauer DC, Browner WS, Cauley JA, Orwoll ES, Scott JC, Black DM, Tao JL, Cummings SR 1993 Factors associated with appendicular bone mass in older women: The study of osteoporotic fractures Research Group Ann Intern Med 118:657665.
  • 58
    Orwoll ES, Bauer DC, Vogt TM, Fox KM 1996 Axial bone mass in older women Ann Intern Med 124:187196.
  • 59
    Glauber HS, Vollmer WM, Nevitt MC, Ensrud KE, Orwoll ES 1995 Body weight versus body fat distribution, adiposity, and frame size as predictors of bone density J Clin Endocrinol Metab 80:11181123.
  • 60
    Keightley PD, Hardge T, May L, Bulfield G 1996 A genetic map of quantitative trait loci for body weight in the mouse Genetics 142:227235.