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  • 1
    Pevny LH, Lovell-Badge R 1997 Sox genes find their feet Curr Opin Genet Dev 7:338344.
  • 2
    Prior HM, Walter MA 1996 Sox genes: Architects of development Mol Med 2:405412.
  • 3
    Sudbeck P, Schmitz ML, Baeuerle PA, Scherer G 1996 Sex reversal by loss of the C-terminal transactivation domain of human Sox9 Nat Genet 13:230232.
  • 4
    Wotton D, Lake RA, Farr CJ, Owen MJ 1995 The high mobility group transcription factor, Sox4, transactivates the human CD2 enhancer J Biol Chem 270:75157522.
  • 5
    Bell DM, Leung KK, Wheatley SC, Ng LJ, Zhou S, Ling KW, Sham MH, Koopman P, Tam PP, Cheah KS 1997 Sox9 directly regulates the type-II collagen gene Nat Genet 16:174178.
  • 6
    Wright E, Hargrave MR, Christiansen J, Cooper L, Kun J, Evans T, Gangadharan U, Greenfield A, Koopman P 1995 The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos Nat Genet 9:1520.
  • 7
    Wagner T, Wirth J, Meyer J, Zabel B, Held M, Zimmer J, Pasantes J, Bricarelli FD, Keutel J, Hustert E, Wolf U, Tommerup N, Schempp W, Scherer G 1994 Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene Sox9 Cell 79:11111120.
  • 8
    Cameron FJ, Hageman RM, Cooke-Yarborough C, Kwok C, Goodwin LL, Sillence DO, Sinclair AH 1996 A novel germ line mutation in Sox9 causes familial campomelic dysplasia and sex reversal Hum Mol Genet 5:16251630.
  • 9
    Lefebvre V, Huang W, Harley VR, Goodfellow PN, De Crombrugghe B 1997 Sox9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1 (II) collagen gene Mol Cell Biol 17:23362346.
  • 10
    Zhao Q, Eberspaecher H, Lefebvre V, De Crombrugghe B 1997 Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis Dev Dyn 209:377386.
  • 11
    Wang EA, Rosen V, Cordes P, Hewick RM, Kriz MJ, Luxenberg DP, Sibley BS, Wozney JM 1988 Purification and characterization of other distinct bone-inducing factors Proc Natl Acad Sci USA 85:94849488.
  • 12
    Duprez DM, Coltey M, Amthor H, Brickell PM, Tickle C 1996 Bone morphogenetic protein-2 (BMP-2) inhibits muscle development and promotes cartilage formation in chick limb bud cultures Dev Biol 174:448452.
  • 13
    Enomoto-Iwamoto M, Iwamoto M, Mukudai Y, Kawakami Y, Nohno T, Higuchi Y, Takemoto S, Ohuchi H, Noji S, Kurisu K 1998 Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes J Cell Biol 140:409418.
  • 14
    Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA 1988 Novel regulators of bone formation: Molecular clones and activities Science 242:15281534.
  • 15
    Wang EA, Rosen V, D'Alessandro JS, Bauduy M, Cordes P, Harada T, Israel DI, Hewick RM, Kerns KM, LaPan P, Luxenberg DP, McQuaid D, Moutsatsos IK, Nove J, Wozney JM 1990 Recombinant human bone morphogenetic protein induces bone formation Proc Natl Acad Sci USA 87:22202224.
  • 16
    Lyons KM, Pelton RW, Hogan BL 1990 Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2a (BMP-2a) Development 109:833844.
  • 17
    Lyons KM, Pelton RW, Hogan BL 1989 Patterns of expression of murine Vgr-1 and BMP-2a mRNA suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development Genes Dev 3:16571658.
  • 18
    Wang EA, Israel DI, Kelly S, Luxenberg DP 1993 Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells Growth Factors 9:5771.
  • 19
    Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S 1991 Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro J Cell Biol 113:681687.
  • 20
    Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney JM, Rosen V, Wang EA, Tanaka H, Omura S, Suda T 1990 The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2 Biochem Biophys Res Commun 172:295299.
  • 21
    Atkinson BL, Fantle KS, Benedict JJ, Huffer WE, Gutierrez-Hartmann A 1997 Combination of osteoinductive bone proteins differentiates mesenchymal C3H10T1/2 cells specifically to the cartilage lineage J Cell Biochem 65:325339.
  • 22
    Laufer E, Nelson CE, Johnson RL, Margan BA, Tabin C 1994 Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud Cell 79:9931003.
  • 23
    Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW 1994 The hedgehog gene family in Drosophila and vertebrate development. Dev Suppl 4351.
  • 24
    Kinto N, Iwamoto M, Enomoto-Iwamoto M, Noji S, Ohuchi H, Yoshioka H, Kataoka H, Wada Y, Yuhao G, Takahashi HE, Yoshiki S, Yamaguchi A 1997 Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation FEBS Lett 404:319323.
  • 25
    Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ 1996 Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein Science 273:613622.
  • 26
    Lanske B, Karaplis AC, Lee K, Luz A, Vortkamp A, Pirro A, Karperien M, Defize LHK, Ho C, Mulligan RC, Abou-Samra AB, Jüppner H, Segre GV, Kronenberg HM 1996 PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth Science 273:663666.
  • 27
    Kronenberg HM, Lee K, Lanske B, Segre GV 1997 Parathyroid hormone-related protein and Indian hedgehog control the pace of cartilage differentiation J Endocrinol 154:S39S45.
  • 28
    Brysch W, Schlingensiepen KH 1994 Design and application of antisense oligonucleotides in cell culture, in vivo, and as therapeutic agents Cell Mol Neurobiol 14:557568.
  • 29
    Gilliland G, Perrin S, Blanchard K, Bunn HF 1990 Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction Proc Natl Acad Sci USA 87:27252729.
  • 30
    Metsaranta M, Toman D, De Crombrugghe B, Vuorio E 1991 Specific hybridization probes for mouse type I, II III and IX collagen mRNAs Biochim Biophys Acta 1089:241243.
  • 31
    Apte SS, Seldin MF, Hayashi M, Olsen BR 1992 Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10 Eur J Biochem 206:217224.
  • 32
    Clover J, Gowen M 1994 Are MG-63 and HOS TE85 human osteosarcoma cell lines representative models of the osteoblastic phenotype? Bone 15:585591.
  • 33
    Reddi AH 1998 Role of morphogenetic proteins in skeletal tissue engineering and regeneration Nat Biotechnol 16:247252.
  • 34
    Kawabata M, Imamura T, Miyazono K 1998 Signal transduction by bone morphogenetic proteins Cytokine Growth Factor Rev 9:4961.
  • 35
    Poole AR, Pidoux I, Reiner A, Choi H, Rosenberg LC 1984 Association of an extracellular protein (chondrocalcin) with the calcification of cartilage in endochondral bone formation J Cell Biol 98:5465.
  • 36
    Massague J, Attisano L, Wrana JL 1994 The TGF-β family and its composite receptors Trends Cell Biol 4:172178.
  • 37
    Ishidou Y, Kitajima I, Obama H, Maruyama I, Murata F, Imamura T, Yamada N, Ten Dijke P, Miyazono K, Sakou T 1995 Enhanced expression of type I receptors for Bone morphogenetic proteins during bone formation J Bone Miner Res 10:16511659.
  • 38
    Dewulf N, Verschueren K, Lonnoy O, Moren A, Grimsby S, Vande Spiegle K, Miyazono K, Huylebroeck D, Ten Dijke P 1995 Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis Endocrinology 136:26522663.
  • 39
    Zou H, Wieser R, Massague J, Niswander L 1997 Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage Genes Dev 11:21912203.
  • 40
    Centrella M, Casinghino S, Kim J, Pham T, Rosen V, Wozney J, McCarthy TL 1995 Independent changes in Type I and Type II receptors for transforming growth factor β induced by bone morphogenetic protein 2 parallel expression of the osteolast phenotype Mol Cell Biol 15:32733281.
  • 41
    Hogan BL 1996 Bone morphogenetic proteins: Multifunctional regulators of vertebrate development Genes Dev 10:15801594.
  • 42
    Nakamura T, Aikawa T, Iwamoto-Enomoto M, Iwamoto M, Higuchi Y, Pacifici M, Kinto N, Yamaguchi A, Noji S, Kurisu K, Matsuya T 1997 Induction of osteogenic differentiation by hedgehog proteins Biochem Biophys Res Commun 237:465469.
  • 43
    Takuwa Y, Ohse C, Wang EA, Wozney JM, Yamashita K 1991 Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3–E1 Biochem Biophys Res Commun 174:96101.
  • 44
    Francis PH, Richardson MK, Brickell PM, Tickle C 1994 Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb Development 120:209218.
  • 45
    Kingsley DM 1994 What do BMPs do in mammals? Clues from the mouse short-ear mutation Trends Genet 10:1621.
  • 46
    Reddi AH 1994 Bone and cartilage differentiation Curr Opin Genet Dev 4:737744.
  • 47
    Chen P, Carrington JL, Hammonds RG, Reddi AH 1991 Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2 Exp Cell Res 195:509515.
  • 48
    van der Rest M, Rosenberg LC, Olsen BR, Poole AR 1986 Chondrocalcin is identical with the C-propeptide of type II procollagen Biochem J 237:923925.
  • 49
    Rosen V, Nove J, Song JJ, Thies S, Cox K, Wozney JM 1994 Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes J Bone Miner 9:17591768.
  • 50
    Zhou G, Lefebvre V, Zhang Z, Eberspaecher H, de Crombrugghe B 1998 Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo J Biol Chem 273:1498914997.
  • 51
    Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, Wright E, Bell DM, Tam PP, Cheah KS, Koopman P 1997 Sox9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse Dev Biol 183:108121.
  • 52
    Yuan H, Corbi N, Basilico C, Dailey L 1995 Developmental-specific activity of the FGF-4 enhancer requires synergistic action of Sox2 and October-3 Genes Dev 9:26352645.
  • 53
    Kosher RA, Kulyk WM, Gay SW 1986 Collagen gene expression during limb cartilage differentiation J Cell Biol 102:11511156.
  • 54
    Hardingham TE, Fosang AJ, Dudhia J 1994 The structure, function and turnover of aggrecan, the large aggregating proteoglycan from cartilage Eur J Clin Chem Clin Biochem 32:249257.
  • 55
    Sandberg M, Vuorio E 1987 Localization of types I, II, and III collagen mRNAs in developing human skeletal tissues by in situ hybridization J Cell Biol 104:10771084.
  • 56
    Neugebauer BM, Moore MA, Broess M, Gerstenfeld LC, Hauschka PV 1995 Characterization of structural sequences in the chicken osteocalcin gene: Expression of osteocalcin by maturing osteoblasts and by hypertrophic chondrocytes in vitro J Bone Miner Res 10:157163.