• 1
    Fujisawa R, Nodasaka Y, Kuboki Y 1995 Further characterization of the interaction between bone sialoprotein (BSP) and collagen Calcif Tissue Int 56:140144.
  • 2
    Goldberg HA, Warner KJ, Stillman MJ, Hunter GK 1996 Determination of the hydroxyapatite-nucleating region of bone sialoprotein Connect Tissue Res 35:385392.
  • 3
    Chen J, Thomas HF, Jin H, Jiang H, Sodek J 1996 Expression of rat bone sialoprotein promoter in transgenic mice J Bone Miner Res 11:654664.
  • 4
    Sodek J, Li JJ, Kim RH, Ogata Y, Yamauchi M 1996 Characterization of the bone sialoprotein (BSP) gene promoter Connect Tissue Res 35:2331.
  • 5
    Kerr JM, Hiscock DR, Grzesik W, Robey PG, Young MF 1997 The human bone sialoprotein gene contains an NF-E1/YY1 cis-acting sequence with putative regulatory activity Calcif Tissue Int 60:276282.
  • 6
    Ducy P, Karsenty G 1995 Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene Mol Cell Biol 15:18581869.
  • 7
    Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G 1997 Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation Cell 89:747754.
  • 8
    Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB 1997 Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex J Cell Biochem 66:18.
  • 9
    Ogawa E, Maruyama M, Kagoshima H, Inuzuka M, Lu J, Satake M, Shigesada K, Ito Y 1993 PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene Proc Natl Acad Sci USA 90:68596863.
  • 10
    Xiao G, Cui Y, Ducy P, Karsenty G, Franceschi RT 1997 Ascorbic acid–dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: Requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence Mol Endocrinol 11:11031113.
  • 11
    Xiao G, Wang D, Benson MD, Ducy P, Karsenty G, Franceschi RT 1998 Role of the α2 integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor J Biol Chem 273:3298832994.
  • 12
    Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T 1997 Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89:755764.
  • 13
    Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ 1997 Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development Cell 89:765771.
  • 14
    Sudo H, Kodama H-A, Amagai Y, Yamamoto S, Kasai S 1983 In vitro differentiation and calcification of a new clonal osteogenic cell line derived from newborn mouse calvaia J Cell Biol 96:191198.
  • 15
    Midura RJ, McQuillan DJ, Benham KJ, Fisher LW, Hascall VC 1990 A rat osteogenic cell line (UMR 106–01) synthesizes a highly sulfated form of bone sialoprotein J Biol Chem 265:52855291.
  • 16
    Yaffe D, Saxel O 1977 Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle Nature 270:725727.
  • 17
    Green H, Meuth M 1974 An established pre-adipose cell line and its differentiation in culture Cell 3:127133.
  • 18
    Majeska RJ, Rodan SB, Rodan GA 1980 Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma Endocrinology 107:14941503.
  • 19
    Strickland S, Mahdavi V 1978 The induction of differentiation in teratocarcinoma stem cells by retinoic acid Cell 15:393403.
  • 20
    Franceschi RT, Iyer BS 1992 Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells J Bone Miner Res 7:235246.
  • 21
    Sambrook J, Frisch EF, Maniatis T Molecular Cloning, A Laboratory Manual, 2nd Ed. Cold Spring Harbor Press, Cold Spring Harbor, NY, U.S.A.
  • 22
    Dignam JD, Martin PL, Shastry S, Roeder RG 1983 Eukaryotic gene transcription with purified components Methods Enzymol 101:582598.
  • 23
    Xiao G, Wang D, Cui Y, Ducy P, Karsenty G, Franceschi RT 1997 Ascorbic acid/ECM-dependent activation of the mouse osteocalcin promoter: Requirement for an intact OSE2 sequence and a2b1 integrin interaction J Bone Miner Res 12 (Suppl 1):S153.
  • 24
    Kim RH, Shapiro HS, Li JJ, Wrana JL, Sodek J 1994 Characterization of the human bone sialoprotein (BSP) gene and its promoter sequence Matrix Biol 14:3140.
  • 25
    Li JJ, Sodek J 1993 Cloning and characterization of the rat bone sialoprotein gene promoter Biochem J 289:625629.
  • 26
    Wang SW, Speck NA 1992 Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers Mol Cell Biol 12:89102.
  • 27
    Kamachi Y, Ogawa E, Asano M, Ishida S, Murakami Y, Satake M, Ito Y, Shigesada K 1990 Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer J Virol 64:48084819.
  • 28
    Geoffroy V, Ducy P, Karsenty G 1995 A PEBP2 alpha/AML-1–related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting element J Biol Chem 270:3097330979.
  • 29
    Meyers S, Downing JR, Hiebert SW 1993 Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: The runt homology domain is required for DNA binding and protein–protein interactions Mol Cell Biol 13:63366345.
  • 30
    Stanford CM, Jacobson PA, Eanes ED, Lembke LA, Midura RJ 1995 Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106–01 BSP) J Biol Chem 270:94209428.
  • 31
    Frendo JL, Xiao G, Fuchs S, Franceschi RT, Karsenty G, Ducy P 1998 Functional hierarchy between two OSE2 elements in the control of osteocalcin expression in vivo J Biol Chem 273:3050930516.
  • 32
    Bedalov A, Salvatori R, Dodig M, Kronenberg MS, Kapural B, Bogdanovic Z, Kream BE, Woody CO, Clark SH, Mack K, Rowe DW, Lichtler AC 1995 Regulation of Col1A1 expression in type I collagen producing tissue: Identification of a 49 base pair region which is regquired for transgene expression in bone of transgenic mice J Bone Miner Res 10:14431451.
  • 33
    Rossert JA, Chen SS, Eberspaecher H, Smith CN, de Crombrugghe B 1996 Identification of a minimal sequence of the mouse pro-alpha 1 (I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts Proc Natl Acad Sci USA 93:10271031.
  • 34
    Benson MD, Cui Y, Aubin JE, Franceschi RT 1997 Cloning and analysis of a 2.5 kb murine bone sialoprotein promoter fragment exhibiting osteoblast-restricted expression J Bone Miner Res 12 (Suppl 1):S277.