“Café-Au-Lait Spots” Caused by Vitiligo in McCune-Albright Syndrome

Authors

  • Michael P. Whyte,

    Corresponding author
    1. Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
    2. Metabolic Research Unit, Shriners Hospital for Children, St. Louis, Missouri, U.S.A.
    • Address reprint requests to: Dr. Michael P. Whyte, Division of Bone and Mineral Diseases, Barnes-Jewish Hospital, Washington University Medical Center, 216 South Kingshighway, St. Louis, MO 63110, U.S.A.
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  • Michelle N. Podgornik,

    1. Metabolic Research Unit, Shriners Hospital for Children, St. Louis, Missouri, U.S.A.
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  • Jan Zerega,

    1. Metabolic Research Unit, Shriners Hospital for Children, St. Louis, Missouri, U.S.A.
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  • William R. Reinus

    1. Department of Radiology, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, Missouri, U.S.A.
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Abstract

Café-au-lait spots, fibrous dysplasia of bone, and endocrine gland hyperactivity are the principal features of McCune-Albright syndrome (MAS). Café-au-lait spots appear at, or soon after, birth. We illustrate “café-au-lait spots” acquired during middle age in a patient with MAS that are an illusion caused by vitiligo. This 64-year-old woman is the oldest patient reported with this disorder.

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