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  • 1
    Mundy GR, Roodman GD 1987 Osteoclast ontogeny and function. J Bone Miner Res 5: 209281.
  • 2
    Suda T, Takahashi N, Martin TJ 1995 Modulation of osteoclast differentiation. Endocr Rev 4: 266270.
  • 3
    Kitazawa R, Kimble RB, Vannice JL, Kung VT, Pacifici R 1994 Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice. J Clin Invest 94: 23972406.
  • 4
    Girasole G, Passeri G, Jilka RL, Manolagas SC 1994 Interleukin-11: A new cytokine critical for osteoclast development. J Clin Invest 93: 15161524.
  • 5
    Onoe Y, Miyaura C, Kaminakayashiki T, Nagai Y, Noguchi K, Chen QR, Seo H, Ohta H, Nozawa S, Suda T 1996 IL-13 and IL-4 inhibit bone resorption by suppressing cyclooxygenase-2-dependent prostaglandin synthesis in osteoblasts. J Immunol 156: 758764.
  • 6
    Tamura T, Udagawa N, Takahashi N, Miyaura C, Tanaka S, Koshihara Y, Ohsugi Y, Kumaki K, Taga T, Kishimoto T, Suda T 1993 Soluble interleukin-6 receptor triggers osteoclast formation by interleukin-6. Proc Natl Acad Sci U S A 90: 1192411928.
  • 7
    Ishimi Y, Miyaura C, Jin CH, Akatsu T, Abe E, Nakamura Y, Yamaguchi A, Yoshiki S, Matsuda T, Hirano T, Kishimoto T, Suda T 1990 IL-6 is produced by osteoblasts and induces bone resorption. J Immunol 145: 32973303.
  • 8
    Pacifici R, Brown C, Puscheck E, Friedrick E, Slatopolsky E, Maggio D, McCracken R, Avioli LV 1991 Effects of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells. Proc Natl Acad U S A 88: 51345138.
  • 9
    Girasole G, Jilka RL, Passeri G, Boswell S, Boder G, Williams DC, Manolagas SC 1992 17β-Estradiol inhibits interleukin-6 production by bone-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteporotic effect of estrogens. J Clin Invest 89: 883891.
  • 10
    Jilka RL, Hangoc G, Girasole G, Passeri G, Williams DC, Abrams JS, Boyce B, Broxmeyer H, Manolagas SC 1992 Increased osteoclast development after estrogen loss: Mediation by interleukin-6. Science 257: 8891.
  • 11
    Miyaura C, Kusano K, Masuzawa T, Chaki O, Onoe Y, Aoyagi M, Sasaki T, Tamura T, Koishihara Y, Ohsugi Y, Suda T 1995 Endogenous bone-resorbing factors in estrogen deficiency: Cooperative effects of IL-1 and IL-6. J Bone Miner Res 10: 13651373.
  • 12
    Kimble RB, Vannice JL, Bloedow DC, Thompson RC, Hopfer W, Kung VT, Brownfield C, Pacifici R 1994 Interleukin-1 receptor antagonist decrease bone loss and bone resorption in ovariectomized rats. J Clin Invest 93: 19591967.
  • 13
    Masuzawa T, Miyaura C, Onoe Y, Kusano K, Ohta H, Nozawa S, Suda T 1994 Estrogen deficiency stimulates B lymphopoiesis in mouse bone marrow. J Clin Invest 94: 10901097.
  • 14
    Miyaura C, Onoe Y, Inada M, Maki K, Ikuta K, Ito M, Suda T 1997 Increased B- lymphopoiesis by interleukin 7 induces bone loss in mice with intact ovarian function: Similarity to estrogen deficiency. Proc Natl Acad Sci U S A 94: 93609365.
  • 15
    Seo H, Miyaura C, Sato S, Sudo T, Suda T 1995 Immature B-lymphopoiesis accumulating in estrogen deficiency stimulate IL-6 production by mouse bone marrow stromal cells. J Bone Miner Res 10: S159.
  • 16
    Wilson CA, Mrose SA, Thomas DW 1995 Enhanced production of B lymphopoiesis after castration. Blood 85: 15351539.
  • 17
    Chaki O, Miyaura C, Seo H, Gorai I, Minaguchi H, Suda T 1996 Androgen deficiency stimulates B-lymphopoiesis in bone marrow and induces bone loss in male mice: Comparison of effects of estrogen and androgen. In: PapapoulosSE, LipsP, PolsHAP, JohnstonCC, DelmasPD (eds.) Osteoporosis. Elsevier Science, Amsterdam, The Netherlands, pp. 3741
  • 18
    Black LJ, Sato M, Rowley ER, Magee DE, Bekele A, Williams DC, Cullinian GJ, Bendele R, Kauffman RF, Bensch WR, Frolik CA, Termine JD, Bryant HU 1994 Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without uterine hypertrophy in ovariectomized rats. J Clin Invest 93: 6369.
  • 19
    Ruegsegger P, Koller B, Muller R 1996 A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int 58: 2429.
  • 20
    Parfitt AM, Mathews CH, Villanueva AR, Kleerekoper M, Frame B, Rao DS 1983 Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss. J Clin Invest 72: 13961409.
  • 21
    Turner CH, Sato M, Bryant HU 1994 Raloxifene preserves bone strength and bone mass in ovariectomized rats. Endocrinology 135: 20012005.
  • 22
    Evans G, Bryant HU, Magee D, Sato M, Turner RT 1994 The effects of raloxifene on tibia histomorphometry in ovariectomized rats. Endocrinology 134: 22832288.
  • 23
    Sato M, Rippy MK, Bryant HU 1996 Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats. FASEB J 10: 905912.
  • 24
    Evans GL, Bryant HU, Magee DE, Turner RT 1996 Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia. Endocrinology 137: 41394144.
  • 25
    Wink CS, Felts WJL 1980 Effects of castration on the bone structure of male rats: A model for osteoporosis. Calcif Tissue Int 32: 7782.
  • 26
    Gill RK, Turner RT, Wronski TJ, Bell NH 1998 Orchidectomy markedly reduces the concentration of the three isoforms of transforming growth factor beta in rat bone, and reduction is prevented by testosterone. Endocrinology 139: 546550.
  • 27
    Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K 1995 Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 80: 36893698.
  • 28
    Zarvis LJ, LeBien TW 1995 Stimulation of human bone marrow stromal cell tyrosine kinases and IL-6 production by contact with B lymphocytes. J Immunol 155: 23592368.
  • 29
    Tanaka Y, Morimoto I, Nakano Y, Okada Y, Hirota S, Nomura S, Nakamura T, Eto S 1995 Osteoblasts are regulated by the cellular adhesion through ICAM-1 and VCAM-1. J Bone Miner Res 10: 13621469.
  • 30
    Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliot R, Colombero A, Elliott G, Scully S, Hsu H, Suillivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ 1998 Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93: 165176.
  • 31
    Yasuda H, Shima N, Nakagawa S, Yamaguchi K, Kinosaki M, Mochizuki S, Tomoyasu A, Yano K, Goto M, Murakimi A, Tsuda E, Morinaga T, Higashio K, Udagawa N, Takahashi N, Suda T 1998 Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci U S A 95: 35973602.
  • 32
    Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, Morony S, Oliveira-dos-Santos AJ, Van G, Itie A, Khoo W, Wakeham A, Dunstan CR, Lacey DL, Mak TW, Boyle WJ, Penninger JM 1999 OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397: 315323.
  • 33
    Yan NN, Venugopalan M, Hardikar S, Glasebrook A 1996 Identification of an estrogen response element activated by metabolites of 17β-estradiol and Raloxifene. Science 273: 12221225.
  • 34
    Kuiper GGJM, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA 1996 Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A 93: 59355930.
  • 35
    Mosselman S, Polman J, Dijkema R 1996 ERβ: Identification and characterization of novel human estrogen receptor. FEBS Lett 392: 4953.
  • 36
    Onoe Y, Miyaura C, Ohta H, Nozawa S, Suda T 1997 Expression of Estrogen receptor β in rat bone. Endocrinology 138: 45094512.
  • 37
    Smithson G, Course JF, Lubahn DB, Korach KS, Kincade PW 1998 The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis. J Immunol 161: 2734.
  • 38
    Kuiper GGJM, Lemmen JG, Carlsson B, Corton JC, Safe SH, Saag PT, Burg B, Gustafsson JA 1998 Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology 139: 42524263.
  • 39
    Byers M, Kuiper GGJM, Gustafsson JA, Park-Sarge OK 1997 Estrogen receptor-β mRNA expression in rat ovary: Down regulation by gonadotropins. Mol Endocrinol 11: 172182.
  • 40
    Prins GS, Marmer M, Woodham C, Chang W, Kuiper G, Gustafsson JA, Birch L 1998 Estrogen receptor-β messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats. Endocrinology 139: 874883.
  • 41
    Peach K, Webb P, Kuiper GGJM, Nilsson S, Gustafsson JA, Kushner PJ, Scanlan TS 1997 Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 277: 15081510.
  • 42
    Delmas PD, Bjarnason NH, Mitlak BH, Ravoux AC, Shah AS, Huster WJ, Draper M, Christiansen C 1997 Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. N Engl J Med 337: 16411647.