• 1
    Caplan AI, Dennis EJ 1996 Mesenchymal stem cells: Progenitors, progeny, and pathways. J Bone Miner Metab 14:193201.
  • 2
    Prockop DJ 1997 Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276:7174.
  • 3
    Pereira RF, Halford WK, O'Hara DM, Leeper BD, Sokolov PB, Pollard DM, Bagasra O, Prockop JD 1995 Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci USA 92:48574861.
  • 4
    Onyia JE, Clapp WD, Long H, Hock MJ 1998 Osteoprogenitor cells as targets for ex vivo gene transfer. J Bone Miner Res 13:2030.
  • 5
    Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G, Mavilio F 1998 Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279:15281530.
  • 6
    Azizi SA, Stokes D, Augelli JB, Di Girolamo C, Prockop JD 1998 Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts. Proc Natl Acad Sci USA 95:39083913.
  • 7
    Marks CS Jr, Hermey DC 1996 The structure and development of bone. In: BilezikianPJ, RaiszLG, RodanGA (eds.) Principles of Bone Biology. Academic Press, Inc., San Diego, CA, USA pp. 314.
  • 8
    Hynes RO, Lander DA 1992 Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 68:303322.
  • 9
    Takeichi M 1995 Morphogenetic roles of classic cadherins. Curr Opin Cell Biol 7:619617.
  • 10
    Overduin M, Harvey ST, Bagby S, Tong IK, Yau P, Takeichi M, Ikura M 1995 Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science 267:386389.
  • 11
    Shapiro L, Fannon MA, Kwong DP, Thompson A, Lehmann SM, Grubel G, Legrand FJ, Als-Nielsen J, Colman RD, Hendrickson AW 1995 Structural basis of cell-cell adhesion by cadherins. Nature 374:327337.
  • 12
    Nagafuchi A, Shirayoshi Y, Okazaki K, Yasuda K, Takeichi M 1987 Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 329:341343.
  • 13
    Miyatani S, Shimamura K, Hatta M, Nagafuchi A, Nose A, Matsunaga M, Hatta K, Takeichi M 1989 Neural cadherin: Role in selective cell-cell adhesion. Science 245:631635.
  • 14
    Nose A, Nagafuchi A, Takeichi M 1987 Isolation of placental cadherin cDNA: Identification of a novel gene family of cell-cell adhesion molecules. EMBO J 6:36553661.
  • 15
    Hutton JC, Christofor G, Chi YW, Edman U, Guest CP, Hanahan D, Kelly BR 1993 Molecular cloning of mouse pancreatic islet R-cadherin: Differential expression in endocrine and exocrine tissue. Mol Endocrinol 7:11511160.
  • 16
    Breier G, Breviario F, Caveda L, Berthier R, Schnurch H, Gotsch U, Vestweber D, Risau W, Dejana E 1996 Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood 87:630641.
  • 17
    Inoue T, Chisaka O, Matsunami H, Takeichi M 1997 Cadherin-6 expression transiently delineates specific rhombomeres, other neural tube subdivisions, and neural crest subpopulations in mouse embryos. Dev Biol 183:183194.
  • 18
    Korematsu K, Redies C 1997 Restricted expression of cadherin-8 in segmental and functional subdivisions of the embryonic mouse brain. Dev Dyn 208:178189.
  • 19
    Okazaki M, Takeshita S, Kawai S, Kikuno R, Tsujimura A, Kudo A, Amann E 2098 1994 Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts. J Biol Chem 269:1209212098.
  • 20
    Donalies M, Cramer M, Ringwald M, Starzinski-Poeitz A 1991 Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells. Proc Natl Acad Sci USA 88:80248028.
  • 21
    Shimoyama Y, Shibata T, Kitajima M, Hirohashi S 1998 Molecular cloning and characterization of a novel human classic cadherin homologous with mouse muscle cadherin. J Biol Chem 273:1001110018.
  • 22
    Friedlander DR, Mege MR, Cunningham AB, Edelman MG 1989 Cell sorting-out is modulated by both the specificity and amount of different cell adhesion molecules (CAMs) expressed on cell surfaces. Proc Natl Acad Sci USA 86:70437047.
  • 23
    Steinberg MS, Takeichi M 1994 Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc Natl Acad Sci USA 91:206209.
  • 24
    Godt D, Tepass U 1998 Drosophila oocyte localization is mediated by differential cadherin-based adhesion. Nature 395:387391.
  • 25
    Niewiadomska P, Godt D, Tepass U 1999 DE-cadherin is required for intercellular motility during Drosophila oogenesis. J Cell Biol 144:533547.
  • 26
    Mbalaviele G, Nishimura R, Myoi A, Niewolna M, Reddy VS, Chen D, Feng J, Roodman D, Mundy RG, Yoneda T 1998 Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation. J Cell Biol 141:14671476.
  • 27
    Cheng SL, Lecanda F, Davidson KM, Warlow MP, Zhang FS, Zhang L, Suzuki S, St John T, Civitelli R 1998 Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation. J Bone Miner Res 13:633644.
  • 28
    Horikawa K, Radice G, Takeichi M, Chisaka O 1999 Adhesive subdivisions intrinsic to the epithelial somites. Dev Biol 215:182189.
  • 29
    Nishikawa S, Ogawa M, Nishikawa S, Kunisada T, Kodama H 1988 B lymphopoiesis on stromal cell clone: Stromal cell clones acting on different stages of B cell differentiation. Eur J Immunol 18:17671771.
  • 30
    Sudo H, Kodama AH, Amagai Y, Yamamoto S, Kasai S 1983 In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96:191198.
  • 31
    Atsumi T, Miwa Y, Kimata K, Ikawa Y 1990 A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ Dev 30:109116.
  • 32
    Kato Y, Windle JJ, Koop AB, Mundy RG, Bonewald FL 1997 Establishment of an osteocyte-like cell line, MLO-Y4. J Bone Miner Res 12:20142023.
  • 33
    Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney MJ, Fujisawa-Sehara A, Suda T 1994 Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127:17551766.
  • 34
    Wang EA, Rosen V, D'Alessandro SJ, Bauduy M, Cordes P, Harada T, Israel ID, Hewick MR, Kerns MK, LaPan P, Luxenberg PD, McQuaid D, Moutsatsos KI, Nove J, Wozeny MJ 1990 Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci USA 87:22202224.
  • 35
    Bennett JH, Joyner JC, Triffitt TJ, Owen EM 1991 Adipocytic cells cultured from marrow have osteogenic potential. J Cell Sci 99:131139.
  • 36
    Beresford JN, Bennett HJ, Devlin C, Leboy SP, Owen EM 1992 Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures. J Cell Sci 102:341351.
  • 37
    Lane MD, Reed CB, Clements RP 1981 Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Prog Clin Biol Res 66:523542.
  • 38
    Pittenger MF, Mackay MA, Beck CS, Jaiswal KR, Douglas R, Mosca DJ, Moorman AM, Simonetti WD, Craig S, Marshak RD 1999 Multilineage potential of adult human mesenchymal stem cells. Science 284:143147.
  • 39
    Shibamoto S, Hayakawa M, Takeuchi K, Hori T, Oku N, Miyazawa K, Kitamura N, Takeichi M, Ito F 1994 Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes Commun 1:295305.
  • 40
    Hatta K, Takeichi M 1986 Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 320:447449.
  • 41
    Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, Kemler R 1996 A role for cadherins in tissue formation. Development 122:31853194.
  • 42
    Cornelison DD, Wold JD 1997 Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells. Dev Biol 191:270283.
  • 43
    Pouliot Y, Gravel M, Holland CP 1994 Developmental regulation of M-cadherin in the terminal differentiation of skeletal myoblasts. Dev Biol 200:305312.
  • 44
    Zeschnigk M, Kozian D, Kuch C, Schmoll M, Starzinski-Powitz A 1995 Involvement of M-cadherin in terminal differentiation of skeletal muscle cells. J Cell Sci 108:29732981.
  • 45
    Rose O, Rohwedel J, Reinhardt S, Bachmann M, Cramer M, Rotter M, Wobus A, Starzinski-Powitz A 1994 Expression of M-cadherin protein in myogenic cells during prenatal mouse development and differentiation of embryonic stem cells in culture. Dev Dyn 201:245259.
  • 46
    Constantinides PG, Jones AP, Gevers W 1977 Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature 267:364366.
  • 47
    Taylor SM, Jones AP 1979 Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17:771779.
  • 48
    Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney MJ, Rosen V, Wang AE, Tanaka H, Omura S, Suda T 1990 The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem Biophys Res Commun 172:295299.
  • 49
    Yamaguchi A, Ishizuya T, Kintou N, Wada Y, Katagiri T, Wozney MJ, Rosen V, Yoshiki S 1996 Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem Biophys Res Commun 220:366371.
  • 50
    Nuttall ME, Patton JA, Olivera LD, Nadeau PD, Gowen M 1998 Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implications for osteopenic disorders. J Bone Miner Res 13:371382.
  • 51
    Kimura Y, Matsunami H, Inoue T, Shimamura K, Uchida N, Ueno T, Miyazaki T, Takeichi M 1995 Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. Dev Biol 169:347358.
  • 52
    Hoffmann I, Balling R 1995 Cloning and expression analysis of a novel mesodermally expressed cadherin. Dev Biol 169:337346.
  • 53
    Navarro P, Ruco L, Dejana E 1998 Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization. J Cell Biol 140:14751484.
  • 54
    Radice GL, Ferreira-Cornwell CM, Robinson DS, Rayburn H, Chodosh AL, Takeichi M, Hynes OR 1997 Precocious mammary gland development in P-cadherin-deficient mice. J Cell Biol 139:10251032.
  • 55
    Kashima T, Kawaguchi J, Takeshita S, Kuroda M, Ishikawa Y, Ishida T, Mori S, Machinami R, Kudo A 1999 Anomalous cadherin expression in osteosarcoma: Possible relationships to metastasis and morphogenesis. Am J Pathol 155:15491555.
  • 56
    Kawaguchi J, Takeshita S, Kashima T, Imai T, Machinami R, Kudo A 1999 Expression and function of the splice variant of the human cadherin-11 gene in subordination to intact cadherin-11. J Bone Miner Res 14:764775.
  • 57
    Kawaguchi J, Azuma Y, Hoshi K, Kii I, Takeshita S, Ohta T, Ozawa H, Takeichi M, Chisaka O, Kudo A 2000 Targeted disruption of cadherin-11 leads to an osteomalacia-like phenotype owing to a reduction in bone density. J Bone Miner Res 15(Suppl 1):S197.
  • 58
    Ferrari SL, Traianedes K, Thorne M, Lafage-Proust M-H, Genever P, Cecchini MG, Behar V, Bisello A, Chorev M, Rosenblatt M, Suva LJ 2000 A role for N-cadherin in the development of the differentiated osteoblastic phenotype. J Bone Miner Res 15:198208.