• 1
    Somjen D, Weisman Y, Harell A, Berger E, Kaye AM 1989 Direct and sex specific stimulation by sex steroids of creatine kinase activity and DNA synthesis in rat bone. Proc Nat Acad Sci USA 86:33613365.
  • 2
    Somjen D, Weisman Y, Mor Z, Harell A, Kaye AM 1990 Regulation of proliferation of rat cartilage and bone by sex steroid hormones. J Steroid Biochem Mol Biol 40:717723.
  • 3
    Fournier B, Haring S, Kaye AM, Somjen D 1996 Stimulation of creatine kinase specific activity in human osteoblast and endometrial cells by estrogens and anti-estrogens and its modulation by calciotropic hormones. J Endocrinol 150:275285.
  • 4
    Katzburg S, Ornoy Y, Hendel D, Lieberherr M, Klein B, Kaye AM, Somjen D 1997 Age and sex dependent stimulation of creatine kinase activity by sex steroids in normal human bone-derived cells in culture. Abstracts of the Annual Meeting of the Israel Calcified Tissues Research Society, Jerusalem, Israel, December, 1997.
  • 5
    Somjen D, Mor Z, Kaye AM 1994 Age dependence and modulation by gonadectomy of the sex-specific response of rat diaphyseal bone to gonadal steroids. Endocrinology 134:809814.
  • 6
    Weisman Y, Cassorla F, Molozowski S, Kreig RJ Jr, Goldray D, Kaye AM, Somjen D 1993 Sex specific response of bone cells to gonadal steroids: Modulation in perinatally androgenized females and testicular feminized male rats. Steroids 8:379388.
  • 7
    Somjen D, Kaye AM, Harell A, Weisman Y 1989 Modulation by vitamin D status of the responsiveness of rat bone to gonadal steroids. Endocrinology 125:18701876.
  • 8
    Kaye AM, Weisman Y, Harell A, Somjen D 1990 Hormonal stimulation of bone cell proliferation. J Steroid Biochem Mol Biol 37:431435.
  • 9
    Somjen D, Harell A, Weisman Y, Kaye AM 1990 Reciprocal modulation by sex steroids and calciotrophic hormones of skeletal cell proliferation. J Steroid Biochem Mol Biol 37:491499.
  • 10
    Sampath TK, Reddi AH 1981 Dissociative extraction and reconstruction of extracellular matrix components involved in local bone differentiation. Proc Natl Acad Sci USA 78:75997603.
  • 11
    Ma S, Chen G, Reddi AH 1990 Collaboration between collagenous matrix and osteogenin is required for bone induction. Ann NY Acad Sci 580:524529.
  • 12
    Hauschka PV, Mavkos AE, Iafrati MD Doleman SE, Klagsburg M 1986 Growth factors in bone matrix. J Biol Chem 261:1266512674.
  • 13
    Centrella M, McCarty TL, Canalis E 1991 Transforming growth factor-beta and remodeling of bone. J Bone Joint Surg Am 73:14181428.
  • 14
    Nilsson OS, Urist MR, Dawson EH, Shmalzries TP, Finerman GA 1986 Bone repair induced by bone morphogenetic protein in ulnar effects in dogs. J Bone Joint Surg Br 68:635642.
  • 15
    Linde A, Hender E 1995 Recombinant bone morphogenetic protein-2 enhances bone healing aided by osteopromotive e-PTFE membranes: An experimental study in rats. Calcif Tissue Int 56:549553.
  • 16
    Rosen V, Nove J, Song JJ, Thies RS, Cox K, Wozney JM 1994 Responsiveness of clonal limb bud cell lines to bone morphogenetic protein-2 reveals a sequential relationship between cartilage and bone cell phenotypes. J Bone Miner Res 9:17591768.
  • 17
    Kubler N, Reuther J, Kirchner T, Pfaff M, Muller-Hermelink HK, Albert R, Sebald W 1994 IgG monoclonal antibodies that inhibit osteoinductivity of human bone matrix-derived proteins (hBMP/NCP). Int J Oral Maxillofac Surg 23:420422.
  • 18
    Gebhart M, Lane JA 1991 Radiographical and biochemical study of demineralized bone matrix implanted into a bone defect of rat femurs with and without bone marrow. Acta Orthop (Belgium) 57:130143.
  • 19
    Long MW, Robinson JA, Ashcraft EA, Mann KG 1995 Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factor. J Clin Invest 95:881887.
  • 20
    Tavassoli M, Maniatis A, Crosby WH 1970 Studies on marrow histogenesis. Proc Soc Exp Biol Med 133:878881.
  • 21
    Tavassoli M, Crosby WH 1968 Transplantation of marrow to extramedullary sites. Science 161:5456.
  • 22
    Friedenstein AJ 1976 Precursor cells of mechanocytes. Int Rev Cytol 47:327359.
  • 23
    Ashton BA, Allen TD, Howlett CR, Eaglesom CC, Hattori A, Owen M 1980 Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin Orthop 151:294307.
  • 24
    Somjen D, Kaye AM, Binderman I 1984 24R,25-Dihydroxy vitamin D stimulates creatine kinase BB activity in chick cartilage cells in culture. FEBS Lett 167:281284.
  • 25
    Somjen D, Binderman I, Weisman Y 1983 The effects of 24R,25-dihydroxycholecalciferol and 1,25-dihydroxycholecalciferol on ornithine decarboxilase activity and on DNA synthesis in the epiphysis and diaphysis of rat bone and in the duodenum. Biochem J 214:293298.
  • 26
    Reiss N, Kaye AM 1981 Identification of the major component of the “estrogen induced protein” of rat uterus as the BB isozyme of creatine kinase. J Biol Chem 256:57415749.
  • 27
    Sampath TK, Reddi AH 1981 Dissociative extraction and reconstruction of extracellular matrix components involved in local bone differentiation. Proc Nat Acad Sci USA 78:75997603.
  • 28
    Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248254.
  • 29
    Komm BS, Terpening CM, Benz DJ, Graeme KM, Gallagos A, Korc M, Greene GL, O'Malley BW, Haussler MR 1988 Estrogen binding, receptor mRNA and biological response in osteoblast-like osteosarcoma cells. Science 241:8184.
  • 30
    Kasperc C, Hemboldt A, Borcsok I, Heuthe S, Cloos O, Niethard F, Ziegler R 1997 Skeletal site-dependent expression of the androgen receptor in human osteoblastic cell populations. Calcif Tissue Int 61:464473.
  • 31
    Walters MR 1981 An estrogen stimulated 1,25-dihydroxyvitamin D receptor in rat uterus. Biochim Biophys Res Commun 103:721726.