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  • 1
    Melton LJ III 1999 Epidemiology of fractures. In: OrwollES (ed.) Osteoporosis in Men: The Effects of Gender on Skeletal Health. Academic Press, San Diego, CA, USA, pp. 113.
  • 2
    Cauley JA, Zmuda JM 1999 Risk factors for fracture in men. In: OrwollES (ed.) Osteoporosis in Men: The Effects of Gender on Skeletal Health. Academic Press, San Diego, CA, USA, pp. 363393.
  • 3
    Nguyen TV, Eisman JA 1999 Risk factors for low bone mass in men. In: OrwollES (ed.) Osteoporosis in Men: The Effects of Gender on Skeletal Health. Academic Press, San Diego, CA, USA, pp. 335361.
  • 4
    Christian JC, Yu PL, Slemenda CW, Johnston CC Jr 1989 Heritability of bone mass: A longitudinal study in aging male twins. Am J Hum Genet 44:429433.
  • 5
    Slemenda CW, Turner CH, Peacock M, Christian JC, Sorbel J, Hui SL, Johnston CC 1996 The genetics of proximal femur geometry, distribution of bone mass and bone mineral density. Osteoporos Int 6:178182.
  • 6
    Arden NK, Baker J, Hogg C, Baan K, Spector TD 1996 The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: A study of postmenopausal twins. J Bone Miner Res 11:530534.
  • 7
    Flicker L, Faulkner KG, Hopper JL, Green RM, Kaymakci B, Nowson CA, Young D, Wark JD 1996 Determinants of hip axis length in women aged 10-89 years: A twin study. Bone 18:4145.
  • 8
    Evans RA, Marel GM, Lancaster EK, Kos S, Evans M, Wong SY 1988 Bone mass is low in relatives of osteoporotic patients. Ann Intern Med 109:870873.
  • 9
    Jouanny P, Guillemin F, Kuntz C, Jeandel C, Pourel J 1995 Environmental and genetic factors affecting bone mass. Similarity of bone density among members of healthy families. Arthritis Rheum 38:6167.
  • 10
    Cohen-Solal ME, Baudoin C, Omouri M, Kuntz D, De Vernejoul MC 1998 Bone mass in middle-aged osteoporotic men and their relatives: Familial effect. J Bone Miner Res 13:19091914.
  • 11
    Diaz MN, O' Neill TW, Silman AJ 1997 The influence of family history of hip fracture on the risk of vertebral deformity in men and women: The European Vertebral Osteoporosis Study. Bone 20:145149.
  • 12
    Zmuda JM, Cauley JA, Nevitt MC, Krishnaswami S, Palermo L, Ferrell RE 2000 Family history and the risk of vertebral fracture in older men. J Bone Miner Res 15:S1;S261.(abstract)
  • 13
    Koller DL, Rodriguez LA, Christian JC, Slemenda CW, Econs MJ, Hui SL, Morin P, Conneally PM, Joslyn G, Curran ME, Peacock M, Johnston CC, Foroud T 1998 Linkage of a QTL contributing to normal variation in bone mineral density to chromosome 11q12-13. J Bone Miner Res 13:19031908.
  • 14
    Niu T, Chen C, Cordell H, Yang J, Wang B, Wang Z, Fang Z, Schork NJ, Rosen CJ, Xu X 1999 A genome-wide scan for loci linked to forearm bone mineral density. Hum Genet 104:226233.
  • 15
    Zmuda JM, Cauley JA, Ferrell RE 1999 Recent progress in understanding the genetic susceptibility to osteoporosis. Genet Epidemiol 16:356367.
  • 16
    Wiren KM, Orwoll ES 1999 Androgens and bone: Basic aspects. In: OrwollES (ed.) Osteoporosis in Men: The Effects of Gender on Skeletal Health. Academic Press, San Diego, CA, USA, pp. 211245.
  • 17
    Miller WL 1988 Molecular biology of steroid hormone synthesis. Endocr Rev 9:295318.
  • 18
    Mayer EI, Homoki J, Ranke MB 1999 Spontaneous growth and bone age development in a patient with 17alpha-hydroxylase deficiency: Evidence of the role of sexual steroids in prepubertal bone maturation. J Pediatr 134:371375.
  • 19
    Peter M, Sippell WG, Wernze H 1993 Diagnosis and treatment of 17-hydroxylase deficiency. J Steroid Biochem Mol Biol 45:107116.
  • 20
    Tourniare J, Audi-Parera L, Loras B, Blum J, Castelnovo P, Forest MG 1976 Male pseudohermaphroditism with hypertension due to a 17α-hydroxylation deficiency. Clin Endocrinol (Oxf) 5:5361.
  • 21
    Yanase T, Kagimoto M, Matsui N, Simpson ER, Waterman MR 1988 Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a stop codon in the N-terminal region of 17 alpha-hydroxylase cytochrome P-450. Mol Cell Endocrinol 59:249253.
  • 22
    Yanase T, Simpson ER, Waterman MR 1991 17 alpha-hydroxylase/17,20-lyase deficiency: From clinical investigation to molecular definition. Endocr Rev 12:91108.
  • 23
    Carey AH, Waterworth D, Patel K, White D, Little J, Novelli P, Franks S, Williamson R 1994 Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet 3:18731876.
  • 24
    Glynn NW, Meilahn EN, Charron M, Anderson SJ, Kuller LH, Cauley JA 1995 Determinants of bone mineral density in older men. J Bone Miner Res 10:17691777.
  • 25
    Miller SA, Dykes DD, Polesky HF 1988 A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:12151219.
  • 26
    Katzman DK, Bachrach LK, Carter DR, Marcus R 1991 Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab 73:13321339.
  • 27
    Furuyama S, Mayes DM, Nugent C 1970 Radioimmunoassay for plasma testosterone. Steroids 16:415428.
  • 28
    Wu CH, Lundy LE 1971 Radioimmunoassay of plasma estrogens. Steroids 18:91111.
  • 29
    Mayes DM, Nugent C 1968 Determination of plasma testosterone by the use of competitive protein binding. J Clin Endocrinol Metab 28:11691176.
  • 30
    Looker AC, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP, Johnston CC Jr, Lindsay RL 1995 Proximal femur bone mineral levels of US adults. Osteoporos Int 5:389409.
  • 31
    Greendale GA, Edelstein S, Barrett-Connor E 1997 Endogenous sex steroids and bone mineral density in older women and men: The Rancho Bernardo Study. J Bone Miner Res 12:18331843.
  • 32
    Preece MA 1996 The genetic contribution to stature. Horm Res 45:5658.
  • 33
    Orwoll ES 1996 Androgens. In: BilezikianJP, RaiszLG, RodanGA (eds.) Principles of Bone Biology. Academic Press, Inc., San Diego, CA, USA, pp. 563580.
  • 34
    Abu EO, Horner A, Kusec V, Triffitt JT, Compston JE 1997 The localization of androgen receptors in human bone. J Clin Endocrinol Metab 82:34933497.
  • 35
    Carrascosa A, Audi L, Ferrandez MA, Ballabriga A 1990 Biological effects of androgens and identification of specific dihydrotestosterone-binding sites in cultured human fetal epiphyseal chondrocytes. J Clin Endocrinol Metab 70:134140.
  • 36
    Kasperk C, Helmboldt A, Borcsok I, Heuthe S, Cloos O, Niethard F, Ziegler R 1997 Skeletal site-dependent expression of the androgen receptor in human osteoblastic cell populations. Calcif Tissue Int 61:464473.
  • 37
    Orwoll ES, Stribrska L, Ramsey EE, Keenan EJ 1991 Androgen receptors in osteoblast-like cell lines. Calcif Tissue Int 49:183187.
  • 38
    Benz DJ, Haussler MR, Thomas MA, Speelman B, Komm BS 1991 High-affinity androgen binding and androgenic regulation of alpha 1(I)-procollagen and transforming growth factor-beta steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. Endocrinology 128:27232730.
  • 39
    Zhang XZ, Kalu DN, Erbas B, Hopper JL, Seeman E 1999 The effects of gonadectomy on bone size, mass, and volumetric density in growing rats are gender-, site-, and growth hormone-specific. J Bone Miner Res 14:802809.
  • 40
    Turner RT, Hannon KS, Demers LM, Buchanan J, Bell NH 1989 Differential effects of gonadal function on bone histomorphometry in male and female rats. J Bone Miner Res 4:557563.
  • 41
    Ren SG, Malozowski S, Sanchez P, Sweet DE, Loriaux DL, Cassorla F 1989 Direct administration of testosterone increases rat tibial epiphyseal growth plate width. Acta Endocrinologica 121:401405.
  • 42
    Jansson JO, Eden S, Isaksson O 1983 Sites of action of testosterone and estradiol on longitudinal bone growth. Am J Physiol 244:E135E140.
  • 43
    Turner RT, Wakley GK, Hannon KS 1990 Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats. J Orthopaed Res 8:612617.
  • 44
    Houchin LD, Rogol AD 1998 Androgen replacement in children with constitutional delay of puberty: The case for aggressive therapy. Baillieres Clin Endocrinol Metab 12:427440.
  • 45
    Krabbe S, Christiansen C, Rodbro P, Transbol I 1979 Effect of puberty on rates of bone growth and mineralisation: With observations in male delayed puberty. Arch Dis Child 54:950953.
  • 46
    Bertelloni S, Baroncelli GI, Battini R, Perri G, Saggese G 1995 Short-term effect of testosterone treatment on reduced bone density in boys with constitutional delay of puberty. J Bone Miner Res 10:14881495.
  • 47
    Crowne EC, Shalet SM, Wallace WH, Eminson DM, Price DA 1990 Final height in boys with untreated constitutional delay in growth and puberty. Arch Dis Child 65:11091112.
  • 48
    Stanhope R, Buchanan CR, Fenn GC, Preece MA 1988 Double blind placebo controlled trial of low dose oxandrolone in the treatment of boys with constitutional delay of growth and puberty. Arch Dis Child 63:501505.
  • 49
    Fox KM, Cummings SR, Powell-Threets K, Stone K 1998 Family history and risk of osteoporotic fracture. Osteoporos Int 8:557562.
  • 50
    Bouxsein ML, Myers ER, Hayes WC 1996 Biomechanics of age-related fractures. In: MarcusR, FeldmanD, KelseyJ (eds.) Osteoporosis. Academic Press, San Diego, CA, USA, pp. 373393.
  • 51
    Peacock M, Turner CH, Liu G, Manatunga AK, Timmerman L, Johnston CC Jr 1995 Better discrimination of hip fracture using bone density, geometry and architecture. Osteoporos Int 5:167173.
  • 52
    Faulkner KG, Cummings SR, Black D, Palermo L, Gluer CC, Genant HK 1993 Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fractures. J Bone Miner Res 8:12111217.
  • 53
    Gluer CC, Cummings SR, Pressman A, Li J, Gluer K, Faulkner KG, Grampp S, Genant HK 1994 Prediction of hip fractures from pelvic radiographs: The study of osteoporotic fractures. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res 9:671677.
  • 54
    Gilsanz V, Loro ML, Roe TF, Sayre J, Gilsanz R, Schulz EE 1995 Vertebral size in elderly women with osteoporosis. Mechanical implications and relationship to fractures. J Clin Invest 95:23322337.
  • 55
    MacGregor AJ, Snieder H, Keen RW, Spector TD 1998 Do different genes determine bone size and bone mineral content? Br J Rheum 37(Suppl):139.(abstract)
  • 56
    Meikle AW, Stringham JD, Bishop DT, West DW 1988 Quantitating genetic and nongenetic factors influencing androgen production and clearance rates in men. J Clin Endocrinol Metab 67:104109.
  • 57
    Harris JA, Vernon PA, Boomsma DI 1988 The heritability of testosterone: A study of Dutch adolescent twins and their parents. Behav Genet 28:165171.
  • 58
    Haiman CA, Hankinson SE, Spiegelman D, Colditz GA, Willett WC, Speizer FE, Kelsey KT, Hunter DJ 1999 The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Res 59:10151020.
  • 59
    Zmuda JM, Cauley JA, Kriska A, Glynn NW, Gutai JP, Kuller LH 1997 Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants. Am J Epidemiol 146:609617.
  • 60
    Lunn RM, Bell DA, Mohler JL, Taylor JA 1999 Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2). Carcinogenesis 20:17271731.
  • 61
    Wadelius M, Andersson SO, Johansson JE, Wadelius C, Rane A 1999 Prostate cancer associated with CYP17 genotype. Pharmacogenetics 9:635639.
  • 62
    Picado-Leonard J, Miller WL 1987 Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): Similarity with the gene for P450c21. DNA 6:439448.
  • 63
    Borroni R, Liu Z, Simpson ER, Hinshelwood MM 1997 A putative binding site for Sp1 is involved in transcriptional regulation of CYP17 gene expression in bovine ovary. Endocrinology 138:20112020.
  • 64
    Nedelcheva Kristensen V, Haraldsen EK, Anderson KB, Lonning PE, Erikstein B, Karesen R, Gabrielsen OS, Borresen-Dale AL 1999 CYP17 and breast cancer risk: The polymorphism in the 5′ flanking area of the gene does not influence binding to Sp-1. Cancer Res 59:28252828.
  • 65
    Lang TF, Keyak JH, Heitz MW, Augat P, Lu Y, Mathur A, Genant HK 1997 Volumetric quantitative computed tomography of the proximal femur: Precision and relation to bone strength. Bone 21:101108.